FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0100, 832 aa 1>>>pF1KE0100 832 - 832 aa - 832 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5248+/-0.000416; mu= 9.4144+/- 0.026 mean_var=276.5642+/-56.738, 0's: 0 Z-trim(121.2): 174 B-trim: 1191 in 1/57 Lambda= 0.077122 statistics sampled from 37198 (37432) to 37198 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.439), width: 16 Scan time: 12.470 The best scores are: opt bits E(85289) NP_003875 (OMIM: 602303) histone acetyltransferase ( 832) 5601 637.2 9.1e-182 XP_005265585 (OMIM: 602303) PREDICTED: histone ace ( 741) 4973 567.3 9.2e-161 XP_016862912 (OMIM: 602303) PREDICTED: histone ace ( 735) 4910 560.2 1.2e-158 XP_016862913 (OMIM: 602303) PREDICTED: histone ace ( 735) 4910 560.2 1.2e-158 NP_066564 (OMIM: 602301) histone acetyltransferase ( 837) 3941 452.5 3.6e-126 XP_006721880 (OMIM: 602301) PREDICTED: histone ace ( 838) 3929 451.2 9.2e-126 XP_016879937 (OMIM: 602301) PREDICTED: histone ace ( 476) 2462 287.7 8.7e-77 XP_006721881 (OMIM: 602301) PREDICTED: histone ace ( 477) 2450 286.3 2.2e-76 XP_011522826 (OMIM: 601819) PREDICTED: nucleosome- (2188) 369 55.5 3e-06 XP_016879843 (OMIM: 601819) PREDICTED: nucleosome- (2327) 369 55.6 3.1e-06 XP_011522828 (OMIM: 601819) PREDICTED: nucleosome- (2776) 369 55.6 3.5e-06 NP_004450 (OMIM: 601819) nucleosome-remodeling fac (2903) 369 55.7 3.6e-06 XP_011522827 (OMIM: 601819) PREDICTED: nucleosome- (2919) 369 55.7 3.6e-06 NP_872579 (OMIM: 601819) nucleosome-remodeling fac (2920) 369 55.7 3.6e-06 XP_005257218 (OMIM: 601819) PREDICTED: nucleosome- (2957) 369 55.7 3.6e-06 XP_005257217 (OMIM: 601819) PREDICTED: nucleosome- (2961) 369 55.7 3.6e-06 XP_011522825 (OMIM: 601819) PREDICTED: nucleosome- (2977) 369 55.7 3.7e-06 XP_005257216 (OMIM: 601819) PREDICTED: nucleosome- (3015) 369 55.7 3.7e-06 XP_011522824 (OMIM: 601819) PREDICTED: nucleosome- (3031) 369 55.7 3.7e-06 XP_005257215 (OMIM: 601819) PREDICTED: nucleosome- (3032) 369 55.7 3.7e-06 XP_016879842 (OMIM: 601819) PREDICTED: nucleosome- (3090) 369 55.7 3.7e-06 XP_005257214 (OMIM: 601819) PREDICTED: nucleosome- (3094) 369 55.7 3.7e-06 XP_011522823 (OMIM: 601819) PREDICTED: nucleosome- (3094) 369 55.7 3.7e-06 XP_005257213 (OMIM: 601819) PREDICTED: nucleosome- (3095) 369 55.7 3.7e-06 XP_005257212 (OMIM: 601819) PREDICTED: nucleosome- (3095) 369 55.7 3.7e-06 XP_005257211 (OMIM: 601819) PREDICTED: nucleosome- (3100) 369 55.7 3.8e-06 XP_005257210 (OMIM: 601819) PREDICTED: nucleosome- (3104) 369 55.7 3.8e-06 XP_005257209 (OMIM: 601819) PREDICTED: nucleosome- (3148) 369 55.7 3.8e-06 XP_011522822 (OMIM: 601819) PREDICTED: nucleosome- (3157) 369 55.7 3.8e-06 XP_005257208 (OMIM: 601819) PREDICTED: nucleosome- (3157) 369 55.7 3.8e-06 XP_005257207 (OMIM: 601819) PREDICTED: nucleosome- (3158) 369 55.7 3.8e-06 NP_001276975 (OMIM: 607576) cat eye syndrome criti (1300) 306 48.3 0.00027 XP_011544434 (OMIM: 607576) PREDICTED: cat eye syn (1409) 306 48.3 0.00029 XP_011544431 (OMIM: 607576) PREDICTED: cat eye syn (1436) 306 48.3 0.00029 XP_011544430 (OMIM: 607576) PREDICTED: cat eye syn (1436) 306 48.3 0.00029 XP_016884274 (OMIM: 607576) PREDICTED: cat eye syn (1463) 306 48.3 0.0003 NP_001276976 (OMIM: 607576) cat eye syndrome criti (1464) 306 48.3 0.0003 XP_011526158 (OMIM: 608749) PREDICTED: bromodomain ( 722) 295 46.7 0.00043 NP_055114 (OMIM: 608749) bromodomain-containing pr ( 722) 295 46.7 0.00043 NP_001317313 (OMIM: 608749) bromodomain-containing ( 794) 295 46.8 0.00046 NP_001106653 (OMIM: 601540) bromodomain-containing ( 801) 291 46.4 0.00063 NP_005095 (OMIM: 601540) bromodomain-containing pr ( 801) 291 46.4 0.00063 NP_001186384 (OMIM: 601540) bromodomain-containing ( 836) 291 46.4 0.00065 NP_490597 (OMIM: 608749) bromodomain-containing pr (1362) 295 47.1 0.00066 XP_011526156 (OMIM: 608749) PREDICTED: bromodomain (1362) 295 47.1 0.00066 XP_011536111 (OMIM: 605682) PREDICTED: bromodomain (1362) 288 46.3 0.0011 NP_001186385 (OMIM: 601540) bromodomain-containing ( 754) 281 45.2 0.0013 XP_011536109 (OMIM: 605682) PREDICTED: bromodomain (1834) 288 46.4 0.0014 XP_016874231 (OMIM: 605682) PREDICTED: bromodomain (1873) 288 46.4 0.0014 XP_011536101 (OMIM: 605682) PREDICTED: bromodomain (1882) 288 46.4 0.0014 >>NP_003875 (OMIM: 602303) histone acetyltransferase KAT (832 aa) initn: 5601 init1: 5601 opt: 5601 Z-score: 3384.3 bits: 637.2 E(85289): 9.1e-182 Smith-Waterman score: 5601; 100.0% identity (100.0% similar) in 832 aa overlap (1-832:1-832) 10 20 30 40 50 60 pF1KE0 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR 730 740 750 760 770 780 790 800 810 820 830 pF1KE0 YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 790 800 810 820 830 >>XP_005265585 (OMIM: 602303) PREDICTED: histone acetylt (741 aa) initn: 4973 init1: 4973 opt: 4973 Z-score: 3007.2 bits: 567.3 E(85289): 9.2e-161 Smith-Waterman score: 4973; 100.0% identity (100.0% similar) in 740 aa overlap (1-740:1-740) 10 20 30 40 50 60 pF1KE0 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR :::::::::::::::::::: XP_005 EPRDPDQLYSTLKSILQQVKI 730 740 >>XP_016862912 (OMIM: 602303) PREDICTED: histone acetylt (735 aa) initn: 4910 init1: 4910 opt: 4910 Z-score: 2969.4 bits: 560.2 E(85289): 1.2e-158 Smith-Waterman score: 4910; 100.0% identity (100.0% similar) in 732 aa overlap (101-832:4-735) 80 90 100 110 120 130 pF1KE0 GSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIV :::::::::::::::::::::::::::::: XP_016 MWTKAEESCKCNGWKNPNPSPTPPRADLQQIIV 10 20 30 140 150 160 170 180 190 pF1KE0 SLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 FKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKM 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 FLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRT 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE0 LLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE0 SASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE0 MTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEER 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE0 RGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIK 400 410 420 430 440 450 560 570 580 590 600 610 pF1KE0 DGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYAD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KE0 EYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEII 520 530 540 550 560 570 680 690 700 710 720 730 pF1KE0 KKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYS 580 590 600 610 620 630 740 750 760 770 780 790 pF1KE0 TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMA 640 650 660 670 680 690 800 810 820 830 pF1KE0 DLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK :::::::::::::::::::::::::::::::::::::::::: XP_016 DLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 700 710 720 730 >>XP_016862913 (OMIM: 602303) PREDICTED: histone acetylt (735 aa) initn: 4910 init1: 4910 opt: 4910 Z-score: 2969.4 bits: 560.2 E(85289): 1.2e-158 Smith-Waterman score: 4910; 100.0% identity (100.0% similar) in 732 aa overlap (101-832:4-735) 80 90 100 110 120 130 pF1KE0 GSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIV :::::::::::::::::::::::::::::: XP_016 MWTKAEESCKCNGWKNPNPSPTPPRADLQQIIV 10 20 30 140 150 160 170 180 190 pF1KE0 SLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 FKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKM 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 FLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRT 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE0 LLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE0 SASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE0 MTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEER 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE0 RGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIK 400 410 420 430 440 450 560 570 580 590 600 610 pF1KE0 DGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYAD 460 470 480 490 500 510 620 630 640 650 660 670 pF1KE0 EYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEII 520 530 540 550 560 570 680 690 700 710 720 730 pF1KE0 KKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYS 580 590 600 610 620 630 740 750 760 770 780 790 pF1KE0 TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMA 640 650 660 670 680 690 800 810 820 830 pF1KE0 DLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK :::::::::::::::::::::::::::::::::::::::::: XP_016 DLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 700 710 720 730 >>NP_066564 (OMIM: 602301) histone acetyltransferase KAT (837 aa) initn: 3534 init1: 2373 opt: 3941 Z-score: 2386.0 bits: 452.5 E(85289): 3.6e-126 Smith-Waterman score: 3941; 71.6% identity (86.4% similar) in 821 aa overlap (22-832:26-837) 10 20 30 40 50 pF1KE0 MSEAGGAGPGGCGAGAGAGAGPGALP-PQPAALP-PAP---PQGSPCAAAAGGSGA : : :.::. : :.: : .: :: ::..:. NP_066 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 CGPATAVAAAGTAEGPGGGG---SARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKC ::... ..::.. :. : . : . .:::.:. :::::::::::.:::::.:.::: NP_066 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 NGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDV ::::::.: :: :: :::: ..:.: :::: : :: ::::::::::.:.:::::.:.:: NP_066 NGWKNPKP-PTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDV 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 EYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNF : :: ::::::.::::::::::::::: ::: .::::::: .::::::.::::: :: NP_066 ENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 VQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCY :::::::: .::::. ::.:::: .:::.::.:.: : :: .:.. :: :::::::: NP_066 VQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 CNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPK :.::: ::::::::::.::::.::::.::: ::::::. : ::::: :::::::::::: NP_066 CHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 FLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN- ::::::::.:. :::::.. : :. : : : : :.... :. . .:. NP_066 FLSMLEEEIYGANSPIWESGFTMPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KE0 -AGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAA .::.: :.: : ::::: . .. .::.::. ::::::::::.:::: ::::::: NP_066 GGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAA 420 430 440 450 460 470 470 480 490 500 510 520 pF1KE0 MLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQL ::::::..:::..::::.::::::::.:::::.::::. : :...:.::::::::::::: NP_066 MLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KE0 PRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYG ::::::::.:::::::::::::::::::::::::::::.::::::::::::::::::::: NP_066 PRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYG 540 550 560 570 580 590 590 600 610 620 630 640 pF1KE0 THLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLM ::::::::::::::.:: ::::::::::::::::::::.::.::..:.:::::::::::: NP_066 THLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLM 600 610 620 630 640 650 650 660 670 680 690 700 pF1KE0 GCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGI :::::::::::.: :::::::::::::::::::::::::::::::.::::::.::.::: NP_066 ECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGI 660 670 680 690 700 710 710 720 730 740 750 760 pF1KE0 RETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRF ::::::: ::::.:: .::::::.:::..: :.::: ::::::::::..::: ::::::: NP_066 RETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRF 720 730 740 750 760 770 770 780 790 800 810 820 pF1KE0 PMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE :.:::::.:::..::::..:::.::::::..::.:::::.::: .::. :::::. :.:: NP_066 PIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 780 790 800 810 820 830 830 pF1KE0 AGLIDK .::::: NP_066 GGLIDK >>XP_006721880 (OMIM: 602301) PREDICTED: histone acetylt (838 aa) initn: 2616 init1: 1455 opt: 3929 Z-score: 2378.8 bits: 451.2 E(85289): 9.2e-126 Smith-Waterman score: 3929; 71.5% identity (86.3% similar) in 822 aa overlap (22-832:26-838) 10 20 30 40 50 pF1KE0 MSEAGGAGPGGCGAGAGAGAGPGALP-PQPAALP-PAP---PQGSPCAAAAGGSGA : : :.::. : :.: : .: :: ::..:. XP_006 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 CGPATAVAAAGTAEGPGGGG---SARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKC ::... ..::.. :. : . : . .:::.:. :::::::::::.:::::.:.::: XP_006 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 NGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDV ::::::.: :: :: :::: ..:.: :::: : :: ::::::::::.:.:::::.:.:: XP_006 NGWKNPKP-PTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDV 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 EYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNF : :: ::::::.::::::::::::::: ::: .::::::: .::::::.::::: :: XP_006 ENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 VQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCY :::::::: .::::. ::.:::: .:::.::.:.: : :: .:.. :: :::::::: XP_006 VQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 CNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPK :.::: ::::::::::.::::.::::.::: ::::::. : ::::: :::::::::::: XP_006 CHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 FLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN- ::::::::.:. :::::.. : :. : : : : :.... :. . .:. XP_006 FLSMLEEEIYGANSPIWESGFTMPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KE0 -AGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAA .::.: :.: : ::::: . .. .::.::. ::::::::::.:::: ::::::: XP_006 GGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAA 420 430 440 450 460 470 470 480 490 500 510 520 pF1KE0 MLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQL ::::::..:::..::::.::::::::.:::::.::::. : :...:.::::::::::::: XP_006 MLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KE0 PRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYG ::::::::.:::::::::::::::::::::::::::::.::::::::::::::::::::: XP_006 PRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYG 540 550 560 570 580 590 590 600 610 620 630 640 pF1KE0 THLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLM ::::::::::::::.:: ::::::::::::::::::::.::.::..:.:::::::::::: XP_006 THLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLM 600 610 620 630 640 650 650 660 670 680 690 700 pF1KE0 GCELNPRIPYTEFSVIIKKQKE-IIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPG :::::::::::.: ::::::: ::::::::::::::::::::::::.::::::.::.:: XP_006 ECELNPRIPYTELSHIIKKQKEVIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPG 660 670 680 690 700 710 710 720 730 740 750 760 pF1KE0 IRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIR :::::::: ::::.:: .::::::.:::..: :.::: ::::::::::..::: :::::: XP_006 IRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIR 720 730 740 750 760 770 770 780 790 800 810 820 pF1KE0 FPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIK ::.:::::.:::..::::..:::.::::::..::.:::::.::: .::. :::::. :.: XP_006 FPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK 780 790 800 810 820 830 830 pF1KE0 EAGLIDK :.::::: XP_006 EGGLIDK >>XP_016879937 (OMIM: 602301) PREDICTED: histone acetylt (476 aa) initn: 2463 init1: 2373 opt: 2462 Z-score: 1499.6 bits: 287.7 E(85289): 8.7e-77 Smith-Waterman score: 2462; 74.7% identity (89.4% similar) in 483 aa overlap (352-832:1-476) 330 340 350 360 370 380 pF1KE0 QLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGI :::::.:. :::::.. : :. : XP_016 MLEEEIYGANSPIWESGFTMPPSE----GT 10 20 390 400 410 420 430 pF1KE0 QTVINPPPVAGTISYNSTSSSLEQPN--AGSSSPACKASSGLEANPGEKRKMTDSHVLEE : : : :.... :. . .:. .::.: :.: : ::::: . .. .::. XP_016 QLVPRPASVSAAVV---PSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLED 30 40 50 60 70 80 440 450 460 470 480 490 pF1KE0 AKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVV ::. ::::::::::.:::: :::::::::::::..:::..::::.::::::::.:::::. XP_016 AKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVI 90 100 110 120 130 140 500 510 520 530 540 550 pF1KE0 GNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGIC ::::. : :...:.:::::::::::::::::::::.:::::::::::::::::::::::: XP_016 GNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGIC 150 160 170 180 190 200 560 570 580 590 600 610 pF1KE0 FRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKK :::::.:::::::::::::::::::::::::::::::::::.:: ::::::::::::::: XP_016 FRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKK 210 220 230 240 250 260 620 630 640 650 660 670 pF1KE0 QGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQA :::::.::.::..:.:::::::::::: :::::::::::.: :::::::::::::::::: XP_016 QGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQA 270 280 290 300 310 320 680 690 700 710 720 730 pF1KE0 QIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQV :::::::::::::.::::::.::.:::::::::: ::::.:: .::::::.:::..: :. XP_016 QIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQI 330 340 350 360 370 380 740 750 760 770 780 790 pF1KE0 KSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNC ::: ::::::::::..::: ::::::::.:::::.:::..::::..:::.::::::..:: XP_016 KSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANC 390 400 410 420 430 440 800 810 820 830 pF1KE0 KEYNPPESEYYKCANILEKFFFSKIKEAGLIDK .:::::.::: .::. :::::. :.::.::::: XP_016 REYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 450 460 470 >>XP_006721881 (OMIM: 602301) PREDICTED: histone acetylt (477 aa) initn: 1545 init1: 1455 opt: 2450 Z-score: 1492.4 bits: 286.3 E(85289): 2.2e-76 Smith-Waterman score: 2450; 74.6% identity (89.3% similar) in 484 aa overlap (352-832:1-477) 330 340 350 360 370 380 pF1KE0 QLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGI :::::.:. :::::.. : :. : XP_006 MLEEEIYGANSPIWESGFTMPPSE----GT 10 20 390 400 410 420 430 pF1KE0 QTVINPPPVAGTISYNSTSSSLEQPN--AGSSSPACKASSGLEANPGEKRKMTDSHVLEE : : : :.... :. . .:. .::.: :.: : ::::: . .. .::. XP_006 QLVPRPASVSAAVV---PSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLED 30 40 50 60 70 80 440 450 460 470 480 490 pF1KE0 AKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVV ::. ::::::::::.:::: :::::::::::::..:::..::::.::::::::.:::::. XP_006 AKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVI 90 100 110 120 130 140 500 510 520 530 540 550 pF1KE0 GNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGIC ::::. : :...:.:::::::::::::::::::::.:::::::::::::::::::::::: XP_006 GNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGIC 150 160 170 180 190 200 560 570 580 590 600 610 pF1KE0 FRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKK :::::.:::::::::::::::::::::::::::::::::::.:: ::::::::::::::: XP_006 FRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKK 210 220 230 240 250 260 620 630 640 650 660 670 pF1KE0 QGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKE-IIKKLIERKQ :::::.::.::..:.:::::::::::: :::::::::::.: ::::::: :::::::::: XP_006 QGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEVIIKKLIERKQ 270 280 290 300 310 320 680 690 700 710 720 730 pF1KE0 AQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQ ::::::::::::::.::::::.::.:::::::::: ::::.:: .::::::.:::..: : XP_006 AQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQ 330 340 350 360 370 380 740 750 760 770 780 790 pF1KE0 VKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTN .::: ::::::::::..::: ::::::::.:::::.:::..::::..:::.::::::..: XP_006 IKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIAN 390 400 410 420 430 440 800 810 820 830 pF1KE0 CKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK :.:::::.::: .::. :::::. :.::.::::: XP_006 CREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 450 460 470 >>XP_011522826 (OMIM: 601819) PREDICTED: nucleosome-remo (2188 aa) initn: 452 init1: 364 opt: 369 Z-score: 233.2 bits: 55.5 E(85289): 3e-06 Smith-Waterman score: 369; 49.5% identity (77.3% similar) in 97 aa overlap (729-825:2075-2171) 700 710 720 730 740 750 pF1KE0 PIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAP : :: .:.....:. ::::.::: ..:: XP_011 EAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAP 2050 2060 2070 2080 2090 2100 760 770 780 790 800 810 pF1KE0 GYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK :: ::. :::: :: ::.. ::: . :.::. ..: ::. ::: .: .:.::..::. XP_011 DYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES 2110 2120 2130 2140 2150 2160 820 830 pF1KE0 FFFSKIKEAGLIDK :: .:.: XP_011 FFVQKLKGFKASRSHNNKLQSTAS 2170 2180 >>XP_016879843 (OMIM: 601819) PREDICTED: nucleosome-remo (2327 aa) initn: 420 init1: 364 opt: 369 Z-score: 232.9 bits: 55.6 E(85289): 3.1e-06 Smith-Waterman score: 369; 49.5% identity (77.3% similar) in 97 aa overlap (729-825:2214-2310) 700 710 720 730 740 750 pF1KE0 PIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAP : :: .:.....:. ::::.::: ..:: XP_016 EAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAP 2190 2200 2210 2220 2230 2240 760 770 780 790 800 810 pF1KE0 GYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK :: ::. :::: :: ::.. ::: . :.::. ..: ::. ::: .: .:.::..::. XP_016 DYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES 2250 2260 2270 2280 2290 2300 820 830 pF1KE0 FFFSKIKEAGLIDK :: .:.: XP_016 FFVQKLKGFKASRSHNNKLQSTAS 2310 2320 832 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:01:20 2016 done: Sat Nov 5 07:01:22 2016 Total Scan time: 12.470 Total Display time: 0.190 Function used was FASTA [36.3.4 Apr, 2011]