FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0101, 182 aa 1>>>pF1KE0101 182 - 182 aa - 182 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8914+/-0.000385; mu= 14.3843+/- 0.024 mean_var=52.5005+/-10.887, 0's: 0 Z-trim(111.1): 18 B-trim: 287 in 1/51 Lambda= 0.177008 statistics sampled from 19584 (19601) to 19584 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.23), width: 16 Scan time: 5.340 The best scores are: opt bits E(85289) NP_057310 (OMIM: 606932) vacuolar protein sorting- ( 182) 1206 315.8 2.5e-86 XP_006719523 (OMIM: 606932) PREDICTED: vacuolar pr ( 183) 1199 314.0 8.6e-86 XP_011536786 (OMIM: 606932) PREDICTED: vacuolar pr ( 183) 1199 314.0 8.6e-86 XP_016874947 (OMIM: 606932) PREDICTED: vacuolar pr ( 183) 1199 314.0 8.6e-86 XP_006719522 (OMIM: 606932) PREDICTED: vacuolar pr ( 183) 1199 314.0 8.6e-86 NP_476528 (OMIM: 606932) vacuolar protein sorting- ( 186) 1199 314.0 8.7e-86 XP_016874946 (OMIM: 606932) PREDICTED: vacuolar pr ( 214) 1199 314.0 9.9e-86 NP_001269079 (OMIM: 606932) vacuolar protein sorti ( 214) 1199 314.0 9.9e-86 NP_001269080 (OMIM: 606932) vacuolar protein sorti ( 91) 453 123.3 1e-28 XP_016874948 (OMIM: 606932) PREDICTED: vacuolar pr ( 123) 446 121.6 4.7e-28 XP_011539754 (OMIM: 611578) PREDICTED: ferric-chel ( 503) 124 39.7 0.009 >>NP_057310 (OMIM: 606932) vacuolar protein sorting-asso (182 aa) initn: 1206 init1: 1206 opt: 1206 Z-score: 1670.9 bits: 315.8 E(85289): 2.5e-86 Smith-Waterman score: 1206; 99.5% identity (99.5% similar) in 182 aa overlap (1-182:1-182) 10 20 30 40 50 60 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_057 GDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 AFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYK 130 140 150 160 170 180 pF1KE0 KP :: NP_057 KP >>XP_006719523 (OMIM: 606932) PREDICTED: vacuolar protei (183 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1661.2 bits: 314.0 E(85289): 8.6e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:3-183) 10 20 30 40 50 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY 130 140 150 160 170 180 180 pF1KE0 KKP ::: XP_006 KKP >>XP_011536786 (OMIM: 606932) PREDICTED: vacuolar protei (183 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1661.2 bits: 314.0 E(85289): 8.6e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:3-183) 10 20 30 40 50 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY 130 140 150 160 170 180 180 pF1KE0 KKP ::: XP_011 KKP >>XP_016874947 (OMIM: 606932) PREDICTED: vacuolar protei (183 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1661.2 bits: 314.0 E(85289): 8.6e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:3-183) 10 20 30 40 50 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY 130 140 150 160 170 180 180 pF1KE0 KKP ::: XP_016 KKP >>XP_006719522 (OMIM: 606932) PREDICTED: vacuolar protei (183 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1661.2 bits: 314.0 E(85289): 8.6e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:3-183) 10 20 30 40 50 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEY 130 140 150 160 170 180 180 pF1KE0 KKP ::: XP_006 KKP >>NP_476528 (OMIM: 606932) vacuolar protein sorting-asso (186 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1661.1 bits: 314.0 E(85289): 8.7e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:6-186) 10 20 30 40 50 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 MAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 HIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 HIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 HKSEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVER :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 HKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVER 130 140 150 160 170 180 180 pF1KE0 IEYKKP :::::: NP_476 IEYKKP >>XP_016874946 (OMIM: 606932) PREDICTED: vacuolar protei (214 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1660.2 bits: 314.0 E(85289): 9.9e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:34-214) 10 20 30 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKI :::::::::::::::::::::::::::::: XP_016 CALRGRDLALAIAGTVSFHGLLRLFRAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 QHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVI 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 PWGDMASLALLQRQFDVDILISGHTHKSEAFEHENKFYINPGSATGAYNALETNIIPSFV ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_016 PWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFV 130 140 150 160 170 180 160 170 180 pF1KE0 LMDIQASTVVTYVYQLIGDDVKVERIEYKKP ::::::::::::::::::::::::::::::: XP_016 LMDIQASTVVTYVYQLIGDDVKVERIEYKKP 190 200 210 >>NP_001269079 (OMIM: 606932) vacuolar protein sorting-a (214 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1660.2 bits: 314.0 E(85289): 9.9e-86 Smith-Waterman score: 1199; 99.4% identity (99.4% similar) in 181 aa overlap (2-182:34-214) 10 20 30 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKI :::::::::::::::::::::::::::::: NP_001 CALRGRDLALAIAGTVSFHGLLRLFRAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 QHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVI 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 PWGDMASLALLQRQFDVDILISGHTHKSEAFEHENKFYINPGSATGAYNALETNIIPSFV ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 PWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFV 130 140 150 160 170 180 160 170 180 pF1KE0 LMDIQASTVVTYVYQLIGDDVKVERIEYKKP ::::::::::::::::::::::::::::::: NP_001 LMDIQASTVVTYVYQLIGDDVKVERIEYKKP 190 200 210 >>NP_001269080 (OMIM: 606932) vacuolar protein sorting-a (91 aa) initn: 458 init1: 446 opt: 453 Z-score: 636.4 bits: 123.3 E(85289): 1e-28 Smith-Waterman score: 453; 76.9% identity (85.7% similar) in 91 aa overlap (1-91:1-86) 10 20 30 40 50 60 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKSE :::::. .: ... : . :. :: . NP_001 GDFDEK-HY---SIICVDGYP-GFYSGHLCVSANWR 70 80 90 130 140 150 160 170 180 pF1KE0 AFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYK >>XP_016874948 (OMIM: 606932) PREDICTED: vacuolar protei (123 aa) initn: 451 init1: 439 opt: 446 Z-score: 624.7 bits: 121.6 E(85289): 4.7e-28 Smith-Waterman score: 446; 76.7% identity (85.6% similar) in 90 aa overlap (2-91:34-118) 10 20 30 pF1KE0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKI :::::::::::::::::::::::::::::: XP_016 CALRGRDLALAIAGTVSFHGLLRLFRAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 QHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVI ::::::::::::::::::::::::::::::::::. .: ... : . :. :: . XP_016 QHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDEK-HY---SIICVDGYP-GFYSGHLCV 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 PWGDMASLALLQRQFDVDILISGHTHKSEAFEHENKFYINPGSATGAYNALETNIIPSFV XP_016 SANWR 120 182 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:12:36 2016 done: Fri Nov 4 03:12:37 2016 Total Scan time: 5.340 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]