FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0102, 359 aa 1>>>pF1KE0102 359 - 359 aa - 359 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0287+/-0.000398; mu= 17.9262+/- 0.025 mean_var=69.5634+/-14.674, 0's: 0 Z-trim(111.3): 240 B-trim: 179 in 1/51 Lambda= 0.153774 statistics sampled from 19589 (19879) to 19589 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.233), width: 16 Scan time: 8.080 The best scores are: opt bits E(85289) NP_001137252 (OMIM: 610820) solute carrier family ( 359) 2392 540.0 3e-153 XP_011523182 (OMIM: 610820) PREDICTED: solute carr ( 365) 2370 535.2 8.9e-152 NP_057100 (OMIM: 610820) solute carrier family 25 ( 351) 2309 521.6 1e-147 NP_001308170 (OMIM: 610820) solute carrier family ( 357) 2287 516.7 3.1e-146 NP_001308169 (OMIM: 610820) solute carrier family ( 336) 1947 441.3 1.5e-123 XP_011523184 (OMIM: 610820) PREDICTED: solute carr ( 342) 1925 436.4 4.4e-122 XP_016880226 (OMIM: 610820) PREDICTED: solute carr ( 258) 1517 345.8 6.3e-95 XP_011523185 (OMIM: 610820) PREDICTED: solute carr ( 264) 1495 340.9 1.9e-93 XP_011523186 (OMIM: 610820) PREDICTED: solute carr ( 264) 1495 340.9 1.9e-93 NP_061331 (OMIM: 610821) solute carrier family 25 ( 338) 1064 245.4 1.4e-64 NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [H ( 338) 359 89.0 1.7e-17 XP_011535589 (OMIM: 607571) PREDICTED: mitochondri ( 303) 343 85.4 1.8e-16 XP_011526228 (OMIM: 610822) PREDICTED: solute carr ( 306) 342 85.2 2.1e-16 NP_077008 (OMIM: 608746) calcium-binding mitochond ( 468) 344 85.8 2.2e-16 XP_011526583 (OMIM: 608746) PREDICTED: calcium-bin ( 515) 344 85.8 2.3e-16 XP_011526580 (OMIM: 608746) PREDICTED: calcium-bin ( 549) 344 85.8 2.5e-16 NP_775908 (OMIM: 610822) solute carrier family 25 ( 370) 342 85.3 2.5e-16 XP_011526579 (OMIM: 608746) PREDICTED: calcium-bin ( 560) 344 85.8 2.5e-16 XP_016882774 (OMIM: 608746) PREDICTED: calcium-bin ( 562) 344 85.8 2.5e-16 XP_011526577 (OMIM: 608746) PREDICTED: calcium-bin ( 577) 344 85.8 2.6e-16 XP_006716415 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 340 84.7 2.6e-16 NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 340 84.7 2.6e-16 XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 340 84.7 2.6e-16 XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 340 84.7 2.6e-16 NP_001304743 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 340 84.7 2.6e-16 XP_011542852 (OMIM: 610387) PREDICTED: mitoferrin- ( 272) 340 84.7 2.6e-16 XP_011526576 (OMIM: 608746) PREDICTED: calcium-bin ( 624) 344 85.9 2.7e-16 XP_016867154 (OMIM: 603471,603859,605814) PREDICTE ( 391) 332 83.1 1.2e-15 XP_016867153 (OMIM: 603471,603859,605814) PREDICTE ( 391) 332 83.1 1.2e-15 XP_016856593 (OMIM: 608744) PREDICTED: calcium-bin ( 271) 330 82.5 1.2e-15 XP_016867152 (OMIM: 603471,603859,605814) PREDICTE ( 672) 332 83.2 1.8e-15 NP_055066 (OMIM: 603471,603859,605814) calcium-bin ( 675) 332 83.2 1.8e-15 NP_001153682 (OMIM: 603471,603859,605814) calcium- ( 676) 332 83.2 1.8e-15 NP_998816 (OMIM: 608744) calcium-binding mitochond ( 458) 330 82.7 1.8e-15 XP_006715894 (OMIM: 603471,603859,605814) PREDICTE ( 686) 332 83.2 1.8e-15 NP_037518 (OMIM: 608744) calcium-binding mitochond ( 477) 330 82.7 1.9e-15 XP_011535590 (OMIM: 607571) PREDICTED: mitochondri ( 269) 326 81.6 2.3e-15 NP_660348 (OMIM: 300641) solute carrier family 25 ( 341) 327 81.9 2.3e-15 NP_001308227 (OMIM: 610822) solute carrier family ( 232) 323 80.9 3.2e-15 XP_005251746 (OMIM: 608745) PREDICTED: calcium-bin ( 366) 316 79.5 1.3e-14 XP_006717012 (OMIM: 608745) PREDICTED: calcium-bin ( 378) 316 79.5 1.4e-14 NP_443133 (OMIM: 608745) calcium-binding mitochond ( 469) 316 79.6 1.6e-14 XP_006717011 (OMIM: 608745) PREDICTED: calcium-bin ( 481) 316 79.6 1.6e-14 NP_001006643 (OMIM: 608745) calcium-binding mitoch ( 489) 316 79.6 1.7e-14 NP_001252543 (OMIM: 608745) calcium-binding mitoch ( 501) 316 79.6 1.7e-14 NP_001006642 (OMIM: 608745) calcium-binding mitoch ( 503) 316 79.6 1.7e-14 NP_001317917 (OMIM: 608745) calcium-binding mitoch ( 515) 316 79.6 1.7e-14 NP_060345 (OMIM: 205950,610819) solute carrier fam ( 304) 299 75.6 1.6e-13 XP_006713277 (OMIM: 205950,610819) PREDICTED: solu ( 300) 296 75.0 2.5e-13 XP_011532171 (OMIM: 205950,610819) PREDICTED: solu ( 298) 293 74.3 3.9e-13 >>NP_001137252 (OMIM: 610820) solute carrier family 25 m (359 aa) initn: 2392 init1: 2392 opt: 2392 Z-score: 2872.3 bits: 540.0 E(85289): 3e-153 Smith-Waterman score: 2392; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 310 320 330 340 350 >>XP_011523182 (OMIM: 610820) PREDICTED: solute carrier (365 aa) initn: 1543 init1: 1543 opt: 2370 Z-score: 2845.9 bits: 535.2 E(85289): 8.9e-152 Smith-Waterman score: 2370; 98.4% identity (98.4% similar) in 365 aa overlap (1-359:1-365) 10 20 30 40 50 60 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFS------ALYW :::::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_011 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSVHPPPQALYW 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 FNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD 310 320 330 340 350 360 pF1KE0 RLLGG ::::: XP_011 RLLGG >>NP_057100 (OMIM: 610820) solute carrier family 25 memb (351 aa) initn: 1938 init1: 1938 opt: 2309 Z-score: 2773.0 bits: 521.6 E(85289): 1e-147 Smith-Waterman score: 2309; 97.5% identity (97.5% similar) in 359 aa overlap (1-359:1-351) 10 20 30 40 50 60 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT ::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YTKW--------KCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 240 250 260 270 280 290 310 320 330 340 350 pF1KE0 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 300 310 320 330 340 350 >>NP_001308170 (OMIM: 610820) solute carrier family 25 m (357 aa) initn: 1285 init1: 1089 opt: 2287 Z-score: 2746.5 bits: 516.7 E(85289): 3.1e-146 Smith-Waterman score: 2287; 95.9% identity (95.9% similar) in 365 aa overlap (1-359:1-357) 10 20 30 40 50 60 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT ::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTKW--------KCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 120 130 140 150 160 170 190 200 210 220 230 pF1KE0 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFS------ALYW :::::::::::::::::::::::::::::::::::::::::::::::::: :::: NP_001 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSVHPPPQALYW 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 FNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD 300 310 320 330 340 350 pF1KE0 RLLGG ::::: NP_001 RLLGG >>NP_001308169 (OMIM: 610820) solute carrier family 25 m (336 aa) initn: 1945 init1: 1945 opt: 1947 Z-score: 2339.2 bits: 441.3 E(85289): 1.5e-123 Smith-Waterman score: 2190; 93.6% identity (93.6% similar) in 359 aa overlap (1-359:1-336) 10 20 30 40 50 60 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMAS------------ 10 20 30 40 70 80 90 100 110 120 pF1KE0 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----------GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 220 230 240 250 260 270 310 320 330 340 350 pF1KE0 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 280 290 300 310 320 330 >>XP_011523184 (OMIM: 610820) PREDICTED: solute carrier (342 aa) initn: 1182 init1: 1096 opt: 1925 Z-score: 2312.7 bits: 436.4 E(85289): 4.4e-122 Smith-Waterman score: 2168; 92.1% identity (92.1% similar) in 365 aa overlap (1-359:1-342) 10 20 30 40 50 60 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMAS------------ 10 20 30 40 70 80 90 100 110 120 pF1KE0 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -----------GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 100 110 120 130 140 150 190 200 210 220 230 pF1KE0 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFS------ALYW :::::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_011 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSVHPPPQALYW 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 FNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVR 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD 280 290 300 310 320 330 pF1KE0 RLLGG ::::: XP_011 RLLGG 340 >>XP_016880226 (OMIM: 610820) PREDICTED: solute carrier (258 aa) initn: 1508 init1: 1508 opt: 1517 Z-score: 1825.2 bits: 345.8 E(85289): 6.3e-95 Smith-Waterman score: 1517; 98.3% identity (98.7% similar) in 236 aa overlap (127-359:23-258) 100 110 120 130 140 150 pF1KE0 WFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL---VMTVPATAIYFTAYDQLKAFLC :::.: :::::::::::::::::::::: XP_016 MVSWSLCTCAQMVPAVPPGFKTLPASLAPWVMTVPATAIYFTAYDQLKAFLC 10 20 30 40 50 160 170 180 190 200 210 pF1KE0 GRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWR 60 70 80 90 100 110 220 230 240 250 260 270 pF1KE0 SLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLT 120 130 140 150 160 170 280 290 300 310 320 330 pF1KE0 LPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPS 180 190 200 210 220 230 340 350 pF1KE0 CAIMISTYEFGKSFFQRLNQDRLLGG :::::::::::::::::::::::::: XP_016 CAIMISTYEFGKSFFQRLNQDRLLGG 240 250 >>XP_011523185 (OMIM: 610820) PREDICTED: solute carrier (264 aa) initn: 855 init1: 855 opt: 1495 Z-score: 1798.7 bits: 340.9 E(85289): 1.9e-93 Smith-Waterman score: 1495; 95.9% identity (96.3% similar) in 242 aa overlap (127-359:23-264) 100 110 120 130 140 150 pF1KE0 WFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL---VMTVPATAIYFTAYDQLKAFLC :::.: :::::::::::::::::::::: XP_011 MVSWSLCTCAQMVPAVPPGFKTLPASLAPWVMTVPATAIYFTAYDQLKAFLC 10 20 30 40 50 160 170 180 190 200 210 pF1KE0 GRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWR 60 70 80 90 100 110 220 230 240 250 260 pF1KE0 SLWLGWGPTALRDVPFS------ALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGT ::::::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_011 SLWLGWGPTALRDVPFSVHPPPQALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGT 120 130 140 150 160 170 270 280 290 300 310 320 pF1KE0 VAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRI 180 190 200 210 220 230 330 340 350 pF1KE0 IKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG :::::::::::::::::::::::::::::::: XP_011 IKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 240 250 260 >>XP_011523186 (OMIM: 610820) PREDICTED: solute carrier (264 aa) initn: 855 init1: 855 opt: 1495 Z-score: 1798.7 bits: 340.9 E(85289): 1.9e-93 Smith-Waterman score: 1495; 95.9% identity (96.3% similar) in 242 aa overlap (127-359:23-264) 100 110 120 130 140 150 pF1KE0 WFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL---VMTVPATAIYFTAYDQLKAFLC :::.: :::::::::::::::::::::: XP_011 MVSWSLCTCAQMVPAVPPGFKTLPASLAPWVMTVPATAIYFTAYDQLKAFLC 10 20 30 40 50 160 170 180 190 200 210 pF1KE0 GRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWR 60 70 80 90 100 110 220 230 240 250 260 pF1KE0 SLWLGWGPTALRDVPFS------ALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGT ::::::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_011 SLWLGWGPTALRDVPFSVHPPPQALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGT 120 130 140 150 160 170 270 280 290 300 310 320 pF1KE0 VAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRI 180 190 200 210 220 230 330 340 350 pF1KE0 IKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG :::::::::::::::::::::::::::::::: XP_011 IKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 240 250 260 >>NP_061331 (OMIM: 610821) solute carrier family 25 memb (338 aa) initn: 1214 init1: 933 opt: 1064 Z-score: 1280.5 bits: 245.4 E(85289): 1.4e-64 Smith-Waterman score: 1162; 50.7% identity (75.1% similar) in 353 aa overlap (4-355:8-335) 10 20 30 40 50 pF1KE0 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRL :. ..:::::.:: :::..::...:::::::.:::.: NP_061 MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQN------------- 10 20 30 40 60 70 80 90 100 110 pF1KE0 WSLSYTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVR . ::. :::..: ::... : .: .:. :.. : : ::.::: ::.: NP_061 -----NPLPK-----GKCFVYSNGLMDHLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIR 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 HEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTV .:: ..:::::: ::::.::::.:::: ::::.:.: .. .. :.::: .::.:.: NP_061 NEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAV 100 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 TVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFN ::::::::.:::.:... :: :: : :.. :: ::: ::.::.::::::::.::.: NP_061 TVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYN 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 YELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVN ::..:.:: . . ..:..:..::. ::: ::::::::::.:. : ..:. ... NP_061 YEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKIS 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE0 -PLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDR :::. :::.... : :..: .:::.:..::.:: ::.::::::::::::.:::. : : NP_061 MPLHM-STWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRR 280 290 300 310 320 330 pF1KE0 LLGG NP_061 QQY 359 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:47:41 2016 done: Sat Nov 5 20:47:42 2016 Total Scan time: 8.080 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]