FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0105, 181 aa 1>>>pF1KE0105 181 - 181 aa - 181 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1131+/-0.000418; mu= 13.7230+/- 0.026 mean_var=70.6665+/-13.988, 0's: 0 Z-trim(111.5): 25 B-trim: 1266 in 1/49 Lambda= 0.152569 statistics sampled from 20042 (20058) to 20042 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.235), width: 16 Scan time: 5.490 The best scores are: opt bits E(85289) NP_113630 (OMIM: 300698) transmembrane protein 47 ( 181) 1216 276.7 1.4e-74 NP_071404 (OMIM: 609301) p53 apoptosis effector re ( 193) 309 77.1 1.9e-14 NP_000295 (OMIM: 118220,118300,139393,145900,16250 ( 160) 142 40.3 0.0019 NP_696997 (OMIM: 118220,118300,139393,145900,16250 ( 160) 142 40.3 0.0019 NP_001268384 (OMIM: 118220,118300,139393,145900,16 ( 160) 142 40.3 0.0019 NP_696996 (OMIM: 118220,118300,139393,145900,16250 ( 160) 142 40.3 0.0019 NP_001268385 (OMIM: 118220,118300,139393,145900,16 ( 160) 142 40.3 0.0019 >>NP_113630 (OMIM: 300698) transmembrane protein 47 [Hom (181 aa) initn: 1216 init1: 1216 opt: 1216 Z-score: 1459.9 bits: 276.7 E(85289): 1.4e-74 Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PASLDIWHCESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 PASLDIWHCESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 AAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDY 130 140 150 160 170 180 pF1KE0 Y : NP_113 Y >>NP_071404 (OMIM: 609301) p53 apoptosis effector relate (193 aa) initn: 203 init1: 94 opt: 309 Z-score: 380.5 bits: 77.1 E(85289): 1.9e-14 Smith-Waterman score: 309; 30.9% identity (63.0% similar) in 181 aa overlap (7-179:5-178) 10 20 30 40 50 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLALCLDLGAVLSPAWV-TADHQYYLSLWESCR :. : . :: :.. :. .:. :. . .:. ..:: ::: .: NP_071 MIRCGLACERCRWILPLLLLS------AIAFDIIALAGRGWLQSSDHGQTSSLWWKCS 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 KPASLDIWH---CESTLSSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVA . .. . . :.: . : :. :.:. : :..: :.......: . : : .. NP_071 QEGGGSGSYEEGCQSLMEYAWGRAAAAMLFCGFIILVICFILSFFALCGPQMLVFLRVIG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VMLFAAVVLQVCSLVLYPIKFIETVSLK----IYHEFNWGYGLAWGATIFSFGGAILYCL .: :.:.:. :::.::.:. .: .:. . . .::.::..:.:::. .: :...: NP_071 GLLALAAVFQIISLVIYPVKYTQTFTLHANPAVTYIYNWAYGFGWAATIILIGCAFFFCC 120 130 140 150 160 170 180 pF1KE0 NPKNYEDYY : :::: NP_071 LP-NYEDDLLGNAKPRYFYTSA 180 190 >>NP_000295 (OMIM: 118220,118300,139393,145900,162500,18 (160 aa) initn: 114 init1: 79 opt: 142 Z-score: 183.0 bits: 40.3 E(85289): 0.0019 Smith-Waterman score: 142; 21.5% identity (59.5% similar) in 158 aa overlap (19-172:3-155) 10 20 30 40 50 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLA-LCLDLGAVLSPAWVTADHQYYLSLWESCR : :.... . .: : : . ... :.... . .::..: NP_000 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNG-HATDLWQNCS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KPASLDIWHCESTLSSDWQI---ATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVA .: .. :: :. ..: ::. : . . . :. :. :... :. ::: NP_000 TSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGG--RFYITGI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 VMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKN ...:.. . . . ..: .. : :. . ....: ::: : ... ....: . NP_000 FQILAGLCV-MSAAAIYTVRHPEW-HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 110 120 130 140 150 180 pF1KE0 YEDYY NP_000 E 160 >>NP_696997 (OMIM: 118220,118300,139393,145900,162500,18 (160 aa) initn: 114 init1: 79 opt: 142 Z-score: 183.0 bits: 40.3 E(85289): 0.0019 Smith-Waterman score: 142; 21.5% identity (59.5% similar) in 158 aa overlap (19-172:3-155) 10 20 30 40 50 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLA-LCLDLGAVLSPAWVTADHQYYLSLWESCR : :.... . .: : : . ... :.... . .::..: NP_696 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNG-HATDLWQNCS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KPASLDIWHCESTLSSDWQI---ATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVA .: .. :: :. ..: ::. : . . . :. :. :... :. ::: NP_696 TSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGG--RFYITGI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 VMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKN ...:.. . . . ..: .. : :. . ....: ::: : ... ....: . NP_696 FQILAGLCV-MSAAAIYTVRHPEW-HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 110 120 130 140 150 180 pF1KE0 YEDYY NP_696 E 160 >>NP_001268384 (OMIM: 118220,118300,139393,145900,162500 (160 aa) initn: 114 init1: 79 opt: 142 Z-score: 183.0 bits: 40.3 E(85289): 0.0019 Smith-Waterman score: 142; 21.5% identity (59.5% similar) in 158 aa overlap (19-172:3-155) 10 20 30 40 50 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLA-LCLDLGAVLSPAWVTADHQYYLSLWESCR : :.... . .: : : . ... :.... . .::..: NP_001 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNG-HATDLWQNCS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KPASLDIWHCESTLSSDWQI---ATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVA .: .. :: :. ..: ::. : . . . :. :. :... :. ::: NP_001 TSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGG--RFYITGI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 VMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKN ...:.. . . . ..: .. : :. . ....: ::: : ... ....: . NP_001 FQILAGLCV-MSAAAIYTVRHPEW-HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 110 120 130 140 150 180 pF1KE0 YEDYY NP_001 E 160 >>NP_696996 (OMIM: 118220,118300,139393,145900,162500,18 (160 aa) initn: 114 init1: 79 opt: 142 Z-score: 183.0 bits: 40.3 E(85289): 0.0019 Smith-Waterman score: 142; 21.5% identity (59.5% similar) in 158 aa overlap (19-172:3-155) 10 20 30 40 50 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLA-LCLDLGAVLSPAWVTADHQYYLSLWESCR : :.... . .: : : . ... :.... . .::..: NP_696 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNG-HATDLWQNCS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KPASLDIWHCESTLSSDWQI---ATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVA .: .. :: :. ..: ::. : . . . :. :. :... :. ::: NP_696 TSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGG--RFYITGI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 VMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKN ...:.. . . . ..: .. : :. . ....: ::: : ... ....: . NP_696 FQILAGLCV-MSAAAIYTVRHPEW-HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 110 120 130 140 150 180 pF1KE0 YEDYY NP_696 E 160 >>NP_001268385 (OMIM: 118220,118300,139393,145900,162500 (160 aa) initn: 114 init1: 79 opt: 142 Z-score: 183.0 bits: 40.3 E(85289): 0.0019 Smith-Waterman score: 142; 21.5% identity (59.5% similar) in 158 aa overlap (19-172:3-155) 10 20 30 40 50 pF1KE0 MASAGSGMEEVRVSVLTPLKLVGLVCIFLA-LCLDLGAVLSPAWVTADHQYYLSLWESCR : :.... . .: : : . ... :.... . .::..: NP_001 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNG-HATDLWQNCS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KPASLDIWHCESTLSSDWQI---ATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVA .: .. :: :. ..: ::. : . . . :. :. :... :. ::: NP_001 TSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGG--RFYITGI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 VMLFAAVVLQVCSLVLYPIKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKN ...:.. . . . ..: .. : :. . ....: ::: : ... ....: . NP_001 FQILAGLCV-MSAAAIYTVRHPEW-HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 110 120 130 140 150 180 pF1KE0 YEDYY NP_001 E 160 181 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:59:41 2016 done: Fri Nov 4 02:59:42 2016 Total Scan time: 5.490 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]