FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0107, 283 aa 1>>>pF1KE0107 283 - 283 aa - 283 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3398+/-0.000465; mu= 10.5997+/- 0.028 mean_var=147.1811+/-30.318, 0's: 0 Z-trim(113.1): 394 B-trim: 34 in 1/51 Lambda= 0.105718 statistics sampled from 21800 (22290) to 21800 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.261), width: 16 Scan time: 6.880 The best scores are: opt bits E(85289) XP_016877356 (OMIM: 604447) PREDICTED: guanine nuc ( 212) 1278 206.8 2.9e-53 XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 1278 206.9 3.7e-53 NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 1278 207.0 4.1e-53 XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 1278 207.0 4.1e-53 NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 1278 207.1 4.4e-53 NP_001269467 (OMIM: 139380,613065,616973) guanine ( 240) 776 130.3 3.6e-30 XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 776 130.4 4.5e-30 XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 776 130.4 4.5e-30 XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 776 130.4 4.5e-30 NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 776 130.4 4.5e-30 NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 776 130.4 4.5e-30 NP_005264 (OMIM: 139390) guanine nucleotide-bindin ( 340) 772 129.8 6.9e-30 XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340) 766 128.9 1.3e-29 NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340) 766 128.9 1.3e-29 XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340) 766 128.9 1.3e-29 NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 763 128.4 1.8e-29 NP_001284500 (OMIM: 139130,145500,617024) guanine ( 339) 739 124.8 2.2e-28 XP_011519255 (OMIM: 139130,145500,617024) PREDICTE ( 360) 625 107.4 4e-23 NP_008882 (OMIM: 601787) transcription initiation ( 800) 389 71.8 4.7e-12 NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 360 66.9 5e-11 NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 360 66.9 5e-11 NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 360 67.2 7.5e-11 NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 360 67.2 7.5e-11 XP_011527969 (OMIM: 601475) PREDICTED: periodic tr ( 734) 323 61.7 4.7e-09 NP_005040 (OMIM: 601475) periodic tryptophan prote ( 919) 323 61.8 5.5e-09 NP_001093207 (OMIM: 616850) WD repeat domain-conta ( 315) 303 58.2 2.2e-08 NP_115708 (OMIM: 616850) WD repeat domain-containi ( 315) 303 58.2 2.2e-08 NP_620640 (OMIM: 601787) transcription initiation ( 745) 307 59.3 2.6e-08 XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 301 58.2 3.9e-08 NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 301 58.2 4.2e-08 NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 301 58.3 4.4e-08 XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 301 58.3 4.6e-08 XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 301 58.3 4.6e-08 XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 301 58.3 4.7e-08 XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 301 58.3 4.7e-08 XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 301 58.3 4.7e-08 XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 301 58.3 4.7e-08 NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 301 58.3 4.7e-08 XP_011510122 (OMIM: 612173) PREDICTED: sperm-assoc ( 569) 292 56.9 1.1e-07 XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 286 55.6 1.3e-07 NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 289 56.3 1.3e-07 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 286 55.7 1.4e-07 NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 285 55.6 1.6e-07 NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 275 54.3 6.5e-07 XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 274 54.2 7.8e-07 NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 274 54.2 7.8e-07 XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 274 54.2 7.8e-07 XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 274 54.2 7.8e-07 XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 274 54.2 7.9e-07 XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 274 54.2 7.9e-07 >>XP_016877356 (OMIM: 604447) PREDICTED: guanine nucleot (212 aa) initn: 1273 init1: 1273 opt: 1278 Z-score: 1077.2 bits: 206.8 E(85289): 2.9e-53 Smith-Waterman score: 1278; 97.4% identity (99.0% similar) in 194 aa overlap (92-283:19-212) 70 80 90 100 110 pF1KE0 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTN--KILTASGDGTCALWDVESGQLLQ :::.. .:::::::::::::::::::::: XP_016 MAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQ 10 20 30 40 120 130 140 150 160 170 pF1KE0 SFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYP 50 60 70 80 90 100 180 190 200 210 220 230 pF1KE0 SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINV 110 120 130 140 150 160 240 250 260 270 280 pF1KE0 WDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA :::::::::::::::::::::::::::::::::::::::::::: XP_016 WDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 170 180 190 200 210 >>XP_011519465 (OMIM: 604447) PREDICTED: guanine nucleot (301 aa) initn: 1273 init1: 1273 opt: 1278 Z-score: 1075.3 bits: 206.9 E(85289): 3.7e-53 Smith-Waterman score: 1436; 76.7% identity (76.7% similar) in 301 aa overlap (53-283:1-301) 30 40 50 60 70 80 pF1KE0 KGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSS :::::::::::::::::::::::::::::: XP_011 MKTRRTLKGHGNKVLCMDWCKDKRRIVSSS 10 20 30 90 pF1KE0 QDGKVIVWDSFTTNK--------------------------------------------- ::::::::::::::: XP_011 QDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENM 40 50 60 70 80 90 100 110 120 130 pF1KE0 -------------------------ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLD ::::::::::::::::::::::::::::::::::: XP_011 AAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLD 100 110 120 130 140 150 140 150 160 170 180 190 pF1KE0 LAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDAT 160 170 180 190 200 210 200 210 220 230 240 250 pF1KE0 CRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF 220 230 240 250 260 270 260 270 280 pF1KE0 GHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::::::::::::::::::::::::::::: XP_011 GHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 280 290 300 >>NP_006569 (OMIM: 604447) guanine nucleotide-binding pr (353 aa) initn: 1273 init1: 1273 opt: 1278 Z-score: 1074.5 bits: 207.0 E(85289): 4.1e-53 Smith-Waterman score: 1525; 77.8% identity (77.8% similar) in 315 aa overlap (39-283:39-353) 10 20 30 40 50 60 pF1KE0 NETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLC :::::::::::::::::::::::::::::: NP_006 NETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLC 10 20 30 40 50 60 70 80 90 pF1KE0 MDWCKDKRRIVSSSQDGKVIVWDSFTTNK------------------------------- ::::::::::::::::::::::::::::: NP_006 MDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNK 70 80 90 100 110 120 100 110 pF1KE0 ---------------------------------------ILTASGDGTCALWDVESGQLL ::::::::::::::::::::: NP_006 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLL 130 140 150 160 170 180 120 130 140 150 160 170 pF1KE0 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYY 190 200 210 220 230 240 180 190 200 210 220 230 pF1KE0 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 250 260 270 280 290 300 240 250 260 270 280 pF1KE0 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::::::::::::::::::::::::::::::::::::::::::: NP_006 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 310 320 330 340 350 >-- initn: 228 init1: 228 opt: 228 Z-score: 209.0 bits: 46.9 E(85289): 6.7e-05 Smith-Waterman score: 228; 100.0% identity (100.0% similar) in 38 aa overlap (1-38:1-38) 10 20 30 40 50 60 pF1KE0 MATEGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLK :::::::::::::::::::::::::::::::::::::: NP_006 MATEGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 GHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKILTASGDGTCALWDVESGQLLQS NP_006 GHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAI 70 80 90 100 110 120 >>XP_011519464 (OMIM: 604447) PREDICTED: guanine nucleot (353 aa) initn: 1273 init1: 1273 opt: 1278 Z-score: 1074.5 bits: 207.0 E(85289): 4.1e-53 Smith-Waterman score: 1525; 77.8% identity (77.8% similar) in 315 aa overlap (39-283:39-353) 10 20 30 40 50 60 pF1KE0 NETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLC :::::::::::::::::::::::::::::: XP_011 SVCPSYTSTQLGRLRPSPTSTTGWLELQDMHQVAERVEALGQFVMKTRRTLKGHGNKVLC 10 20 30 40 50 60 70 80 90 pF1KE0 MDWCKDKRRIVSSSQDGKVIVWDSFTTNK------------------------------- ::::::::::::::::::::::::::::: XP_011 MDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNK 70 80 90 100 110 120 100 110 pF1KE0 ---------------------------------------ILTASGDGTCALWDVESGQLL ::::::::::::::::::::: XP_011 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLL 130 140 150 160 170 180 120 130 140 150 160 170 pF1KE0 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYY 190 200 210 220 230 240 180 190 200 210 220 230 pF1KE0 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 250 260 270 280 290 300 240 250 260 270 280 pF1KE0 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::::::::::::::::::::::::::::::::::::::::::: XP_011 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 310 320 330 340 350 >>NP_057278 (OMIM: 604447) guanine nucleotide-binding pr (395 aa) initn: 1273 init1: 1273 opt: 1278 Z-score: 1073.9 bits: 207.1 E(85289): 4.4e-53 Smith-Waterman score: 1525; 77.8% identity (77.8% similar) in 315 aa overlap (39-283:81-395) 10 20 30 40 50 60 pF1KE0 NETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLC :::::::::::::::::::::::::::::: NP_057 NETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLC 60 70 80 90 100 110 70 80 90 pF1KE0 MDWCKDKRRIVSSSQDGKVIVWDSFTTNK------------------------------- ::::::::::::::::::::::::::::: NP_057 MDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNK 120 130 140 150 160 170 100 110 pF1KE0 ---------------------------------------ILTASGDGTCALWDVESGQLL ::::::::::::::::::::: NP_057 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLL 180 190 200 210 220 230 120 130 140 150 160 170 pF1KE0 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYY 240 250 260 270 280 290 180 190 200 210 220 230 pF1KE0 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 300 310 320 330 340 350 240 250 260 270 280 pF1KE0 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::::::::::::::::::::::::::::::::::::::::::: NP_057 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 360 370 380 390 >-- initn: 228 init1: 228 opt: 228 Z-score: 208.4 bits: 46.9 E(85289): 7.2e-05 Smith-Waterman score: 228; 100.0% identity (100.0% similar) in 38 aa overlap (1-38:43-80) 10 20 30 pF1KE0 MATEGLHENETLASLKSEAESLKGKLEEER :::::::::::::::::::::::::::::: NP_057 SCDKCFKQRALRPVFKKSQQLSYCSTCAEIMATEGLHENETLASLKSEAESLKGKLEEER 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE0 AKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVW :::::::: NP_057 AKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVW 80 90 100 110 120 130 >>NP_001269467 (OMIM: 139380,613065,616973) guanine nucl (240 aa) initn: 882 init1: 615 opt: 776 Z-score: 662.7 bits: 130.3 E(85289): 3.6e-30 Smith-Waterman score: 776; 57.2% identity (81.8% similar) in 187 aa overlap (96-282:55-239) 70 80 90 100 110 120 pF1KE0 VLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKILTASGDGTCALWDVESGQLLQSFHGHG :.:.:.::: ::::::.:.:: .: :: NP_001 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 30 40 50 60 70 80 130 140 150 160 170 180 pF1KE0 ADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFA .::. :.:::. ::::.:: .: .::.: :.: :.: ::::::.. ..:.:.::: NP_001 GDVMSLSLAPDTR--LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFA 90 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 SGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKG .:::::::::.:::::.:. ::...:: : .::.:: :::::.:::.:.. ::::.::. NP_001 TGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA 150 160 170 180 190 200 250 260 270 280 pF1KE0 SRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA .:...: ::.:::: : :. :: : .:::: :..: NP_001 DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 210 220 230 240 >>XP_016856549 (OMIM: 139380,613065,616973) PREDICTED: g (340 aa) initn: 1199 init1: 615 opt: 776 Z-score: 660.9 bits: 130.4 E(85289): 4.5e-30 Smith-Waterman score: 860; 43.8% identity (63.8% similar) in 315 aa overlap (35-282:27-339) 10 20 30 40 50 60 pF1KE0 GLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGN :. : :... .. .:.. :.:::::.:: XP_016 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLA 10 20 30 40 50 70 80 90 pF1KE0 KVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNK--------------------------- :. : : :.: .::.:::::.:.:::.:::: XP_016 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 60 70 80 90 100 110 100 110 pF1KE0 ----------------------------------------ILTASGDGTCALWDVESGQL :.:.::: ::::::.:.:: XP_016 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ 120 130 140 150 160 170 120 130 140 150 160 170 pF1KE0 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY .: :: .::. :.:::. ::::.:: .: .::.: :.: :.: ::::::.. . XP_016 TTTFTGHTGDVMSLSLAPDTR--LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICF 180 190 200 210 220 230 180 190 200 210 220 230 pF1KE0 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI .:.:.:::.:::::::::.:::::.:. ::...:: : .::.:: :::::.:::.:.. XP_016 FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNC 240 250 260 270 280 290 240 250 260 270 280 pF1KE0 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::.::..:...: ::.:::: : :. :: : .:::: :..: XP_016 NVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 300 310 320 330 340 >>XP_016856550 (OMIM: 139380,613065,616973) PREDICTED: g (340 aa) initn: 1199 init1: 615 opt: 776 Z-score: 660.9 bits: 130.4 E(85289): 4.5e-30 Smith-Waterman score: 860; 43.8% identity (63.8% similar) in 315 aa overlap (35-282:27-339) 10 20 30 40 50 60 pF1KE0 GLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGN :. : :... .. .:.. :.:::::.:: XP_016 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLA 10 20 30 40 50 70 80 90 pF1KE0 KVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNK--------------------------- :. : : :.: .::.:::::.:.:::.:::: XP_016 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 60 70 80 90 100 110 100 110 pF1KE0 ----------------------------------------ILTASGDGTCALWDVESGQL :.:.::: ::::::.:.:: XP_016 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ 120 130 140 150 160 170 120 130 140 150 160 170 pF1KE0 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY .: :: .::. :.:::. ::::.:: .: .::.: :.: :.: ::::::.. . XP_016 TTTFTGHTGDVMSLSLAPDTR--LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICF 180 190 200 210 220 230 180 190 200 210 220 230 pF1KE0 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI .:.:.:::.:::::::::.:::::.:. ::...:: : .::.:: :::::.:::.:.. XP_016 FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNC 240 250 260 270 280 290 240 250 260 270 280 pF1KE0 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::.::..:...: ::.:::: : :. :: : .:::: :..: XP_016 NVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 300 310 320 330 340 >>XP_016856548 (OMIM: 139380,613065,616973) PREDICTED: g (340 aa) initn: 1199 init1: 615 opt: 776 Z-score: 660.9 bits: 130.4 E(85289): 4.5e-30 Smith-Waterman score: 860; 43.8% identity (63.8% similar) in 315 aa overlap (35-282:27-339) 10 20 30 40 50 60 pF1KE0 GLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGN :. : :... .. .:.. :.:::::.:: XP_016 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLA 10 20 30 40 50 70 80 90 pF1KE0 KVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNK--------------------------- :. : : :.: .::.:::::.:.:::.:::: XP_016 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 60 70 80 90 100 110 100 110 pF1KE0 ----------------------------------------ILTASGDGTCALWDVESGQL :.:.::: ::::::.:.:: XP_016 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ 120 130 140 150 160 170 120 130 140 150 160 170 pF1KE0 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY .: :: .::. :.:::. ::::.:: .: .::.: :.: :.: ::::::.. . XP_016 TTTFTGHTGDVMSLSLAPDTR--LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICF 180 190 200 210 220 230 180 190 200 210 220 230 pF1KE0 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI .:.:.:::.:::::::::.:::::.:. ::...:: : .::.:: :::::.:::.:.. XP_016 FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNC 240 250 260 270 280 290 240 250 260 270 280 pF1KE0 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::.::..:...: ::.:::: : :. :: : .:::: :..: XP_016 NVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 300 310 320 330 340 >>NP_002065 (OMIM: 139380,613065,616973) guanine nucleot (340 aa) initn: 1199 init1: 615 opt: 776 Z-score: 660.9 bits: 130.4 E(85289): 4.5e-30 Smith-Waterman score: 860; 43.8% identity (63.8% similar) in 315 aa overlap (35-282:27-339) 10 20 30 40 50 60 pF1KE0 GLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGN :. : :... .. .:.. :.:::::.:: NP_002 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLA 10 20 30 40 50 70 80 90 pF1KE0 KVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNK--------------------------- :. : : :.: .::.:::::.:.:::.:::: NP_002 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 60 70 80 90 100 110 100 110 pF1KE0 ----------------------------------------ILTASGDGTCALWDVESGQL :.:.::: ::::::.:.:: NP_002 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ 120 130 140 150 160 170 120 130 140 150 160 170 pF1KE0 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY .: :: .::. :.:::. ::::.:: .: .::.: :.: :.: ::::::.. . NP_002 TTTFTGHTGDVMSLSLAPDTR--LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICF 180 190 200 210 220 230 180 190 200 210 220 230 pF1KE0 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI .:.:.:::.:::::::::.:::::.:. ::...:: : .::.:: :::::.:::.:.. NP_002 FPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNC 240 250 260 270 280 290 240 250 260 270 280 pF1KE0 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA ::::.::..:...: ::.:::: : :. :: : .:::: :..: NP_002 NVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 300 310 320 330 340 283 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:55:07 2016 done: Fri Nov 4 02:55:08 2016 Total Scan time: 6.880 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]