FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0112, 195 aa 1>>>pF1KE0112 195 - 195 aa - 195 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.5045+/-0.000331; mu= -3.9245+/- 0.021 mean_var=249.4918+/-50.834, 0's: 0 Z-trim(124.5): 8 B-trim: 1229 in 2/53 Lambda= 0.081198 statistics sampled from 46274 (46283) to 46274 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.543), width: 16 Scan time: 6.380 The best scores are: opt bits E(85289) NP_075385 (OMIM: 602940) MARCKS-related protein [H ( 195) 1284 161.9 5.8e-40 NP_002347 (OMIM: 177061) myristoylated alanine-ric ( 332) 310 48.0 2e-05 >>NP_075385 (OMIM: 602940) MARCKS-related protein [Homo (195 aa) initn: 1284 init1: 1284 opt: 1284 Z-score: 838.4 bits: 161.9 E(85289): 5.8e-40 Smith-Waterman score: 1284; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KE0 MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLSPKGEGESPPVNGTDEAAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_075 MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLSPKGEGESPPVNGTDEAAGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TGDAIEPAPPSQGAEAKGEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_075 TGDAIEPAPPSQGAEAKGEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PTEEEQEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASEEEAGPQATEPSTPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_075 PTEEEQEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASEEEAGPQATEPSTPS 130 140 150 160 170 180 190 pF1KE0 GPESGPTPASAEQNE ::::::::::::::: NP_075 GPESGPTPASAEQNE 190 >>NP_002347 (OMIM: 177061) myristoylated alanine-rich C- (332 aa) initn: 359 init1: 163 opt: 310 Z-score: 218.6 bits: 48.0 E(85289): 2e-05 Smith-Waterman score: 310; 36.3% identity (58.2% similar) in 201 aa overlap (4-195:71-263) 10 20 30 pF1KE0 MGSQSSKAPRGDVTAEEAAGASPAKANGQENGH . . : : .. : . :: : . : : NP_002 VNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGA 50 60 70 80 90 100 40 50 60 70 80 90 pF1KE0 VKSNGDLSPKGEGESP--PVNGTDEAAGATGDAIEPAPPSQGAEAKGEVPPKETPKKKKK . . .::. : :. . :::.:.... : . :: . : .:::::::: NP_002 SPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAED-GATPS---PSNETPKKKKK 110 120 130 140 150 100 110 120 130 140 pF1KE0 -FSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEE---EQEQGEIGACSDEGTAQEGKAAA ::::: :::::.:::.:.::.: . : .:. : .. : .: . :. : :. :: NP_002 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 160 170 180 190 200 210 150 160 170 180 190 pF1KE0 TPESQEPQAKGAEASAASE-EEAGPQ--ATEPSTPSGPESGPTPASAEQNE .: : : : :..:... .:: :: :. : : : : : :. : .. NP_002 AP--GEEAAAGEEGAAGGDPQEAKPQEAAVAPEKP--PASDETKAAEEPSKVEEKKAEEA 220 230 240 250 260 270 NP_002 GASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 280 290 300 310 320 330 195 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:33:28 2016 done: Fri Nov 4 02:33:29 2016 Total Scan time: 6.380 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]