FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0114, 308 aa 1>>>pF1KE0114 308 - 308 aa - 308 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2366+/-0.000681; mu= 15.8358+/- 0.041 mean_var=62.4519+/-12.260, 0's: 0 Z-trim(109.6): 16 B-trim: 0 in 0/51 Lambda= 0.162294 statistics sampled from 11015 (11022) to 11015 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.339), width: 16 Scan time: 2.360 The best scores are: opt bits E(32554) CCDS12387.1 COPE gene_id:11316|Hs108|chr19 ( 308) 2016 480.2 8.5e-136 CCDS12389.1 COPE gene_id:11316|Hs108|chr19 ( 256) 1242 299.0 2.6e-81 CCDS12388.1 COPE gene_id:11316|Hs108|chr19 ( 257) 1050 254.0 8.9e-68 CCDS82321.1 COPE gene_id:11316|Hs108|chr19 ( 331) 1047 253.4 1.8e-67 >>CCDS12387.1 COPE gene_id:11316|Hs108|chr19 (308 aa) initn: 2016 init1: 2016 opt: 2016 Z-score: 2551.5 bits: 480.2 E(32554): 8.5e-136 Smith-Waterman score: 2016; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 250 260 270 280 290 300 pF1KE0 VLQYAPSA :::::::: CCDS12 VLQYAPSA >>CCDS12389.1 COPE gene_id:11316|Hs108|chr19 (256 aa) initn: 1242 init1: 1242 opt: 1242 Z-score: 1573.3 bits: 299.0 E(32554): 2.6e-81 Smith-Waterman score: 1547; 83.1% identity (83.1% similar) in 308 aa overlap (1-308:1-256) 10 20 30 40 50 60 pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ ::::::::::::: CCDS12 LTQLATAWVSLAT----------------------------------------------- 190 250 260 270 280 290 300 pF1KE0 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 -----DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 200 210 220 230 240 pF1KE0 VLQYAPSA :::::::: CCDS12 VLQYAPSA 250 >>CCDS12388.1 COPE gene_id:11316|Hs108|chr19 (257 aa) initn: 1045 init1: 1045 opt: 1050 Z-score: 1330.3 bits: 254.0 E(32554): 8.9e-68 Smith-Waterman score: 1570; 83.1% identity (83.1% similar) in 308 aa overlap (1-308:1-257) 10 20 30 40 50 60 pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL :::::::::::::::::::::::::::::::::::: CCDS12 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRS----------------------- 70 80 90 130 140 150 160 170 180 pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT :::::::::::::::::::::::::::::::: CCDS12 ----------------------------TAMTVQILLKLDRLDLARKELKRMQDLDEDAT 100 110 120 190 200 210 220 230 240 pF1KE0 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 130 140 150 160 170 180 250 260 270 280 290 300 pF1KE0 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 190 200 210 220 230 240 pF1KE0 VLQYAPSA :::::::: CCDS12 VLQYAPSA 250 >>CCDS82321.1 COPE gene_id:11316|Hs108|chr19 (331 aa) initn: 1989 init1: 1045 opt: 1047 Z-score: 1324.8 bits: 253.4 E(32554): 1.8e-67 Smith-Waterman score: 1943; 92.7% identity (92.7% similar) in 331 aa overlap (1-308:1-331) 10 20 30 40 50 60 pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 70 80 90 100 110 120 130 140 150 pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLE-----------------------CTAMTVQILL ::::::::::::::::::::::::::: ::::::::: CCDS82 LMAASIYLHDQNPDAALRALHQGDSLEWVSSPGRALHLEAQPMEAASPDGRTAMTVQILL 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 KLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE0 LLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL 250 260 270 280 290 300 280 290 300 pF1KE0 KDAHRSHPFIKEYQAKENDFDRLVLQYAPSA ::::::::::::::::::::::::::::::: CCDS82 KDAHRSHPFIKEYQAKENDFDRLVLQYAPSA 310 320 330 308 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:31:22 2016 done: Fri Nov 4 02:31:22 2016 Total Scan time: 2.360 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]