FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0118, 195 aa 1>>>pF1KE0118 195 - 195 aa - 195 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1686+/-0.000822; mu= 13.2758+/- 0.049 mean_var=53.1058+/-10.840, 0's: 0 Z-trim(105.1): 12 B-trim: 0 in 0/47 Lambda= 0.175996 statistics sampled from 8222 (8228) to 8222 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.253), width: 16 Scan time: 1.520 The best scores are: opt bits E(32554) CCDS8268.1 TMEM126A gene_id:84233|Hs108|chr11 ( 195) 1267 329.4 8.3e-91 CCDS58165.1 TMEM126A gene_id:84233|Hs108|chr11 ( 125) 830 218.4 1.4e-57 CCDS53686.1 TMEM126B gene_id:55863|Hs108|chr11 ( 200) 287 80.6 6.9e-16 CCDS8267.2 TMEM126B gene_id:55863|Hs108|chr11 ( 230) 287 80.6 7.8e-16 >>CCDS8268.1 TMEM126A gene_id:84233|Hs108|chr11 (195 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1743.7 bits: 329.4 E(32554): 8.3e-91 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KE0 MENHKSNNKENITIVDISRKINQLPEAERNLLENGSVYVGLNAALCGLIANSLFRRILNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MENHKSNNKENITIVDISRKINQLPEAERNLLENGSVYVGLNAALCGLIANSLFRRILNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLTGLVIGGLYPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLTGLVIGGLYPVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMFSAYLGSEQYKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMFSAYLGSEQYKL 130 140 150 160 170 180 190 pF1KE0 LIKALQLSEPGKEIH ::::::::::::::: CCDS82 LIKALQLSEPGKEIH 190 >>CCDS58165.1 TMEM126A gene_id:84233|Hs108|chr11 (125 aa) initn: 830 init1: 830 opt: 830 Z-score: 1147.2 bits: 218.4 E(32554): 1.4e-57 Smith-Waterman score: 830; 100.0% identity (100.0% similar) in 125 aa overlap (71-195:1-125) 50 60 70 80 90 100 pF1KE0 LNAALCGLIANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCET :::::::::::::::::::::::::::::: CCDS58 MAGIPFLTTDLTYRCFVSFPLNTGDLDCET 10 20 30 110 120 130 140 150 160 pF1KE0 CTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKML 40 50 60 70 80 90 170 180 190 pF1KE0 FPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH ::::::::::::::::::::::::::::::::::: CCDS58 FPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH 100 110 120 >>CCDS53686.1 TMEM126B gene_id:55863|Hs108|chr11 (200 aa) initn: 258 init1: 173 opt: 287 Z-score: 398.8 bits: 80.6 E(32554): 6.9e-16 Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:19-194) 10 20 30 40 pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSVYVGLNAALCGLI .. ..: : .... : : .:. . .. : .:.. :.. CCDS53 MAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT--FGTTAGFSGIF 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 ANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLT .: :::: ..: . . . .: .:::.: .: . :: : . ... :.: . ::.: CCDS53 SNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNISKENC-VFRSSLI 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 GLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMF :.: : .:: ::. :: ::..:... :: :: .: .:. . .. : .:...: :: CCDS53 GIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMKLMAIPLVFQIMF 120 130 140 150 160 170 170 180 190 pF1KE0 SAYLGSEQYKLLIKALQLSEPGKEIH . : .: .. ..:. CCDS53 GILNGLYHYAVFEETLEKTIHEE 180 190 200 >>CCDS8267.2 TMEM126B gene_id:55863|Hs108|chr11 (230 aa) initn: 258 init1: 173 opt: 287 Z-score: 397.8 bits: 80.6 E(32554): 7.8e-16 Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:49-224) 10 20 30 pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSV .. ..: : .... : : .:. . .. CCDS82 PVGTEEAPKVFKMAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT- 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE0 YVGLNAALCGLIANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLD : .:.. :...: :::: ..: . . . .: .:::.: .: . :: : . ... CCDS82 -FGTTAGFSGIFSNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNIS 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE0 CETCTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFR :.: . ::.: :.: : .:: ::. :: ::..:... :: :: .: .:. . .. CCDS82 KENC-VFRSSLIGIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMK 140 150 160 170 180 190 160 170 180 190 pF1KE0 KMLFPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH : .:...: ::. : .: .. ..:. CCDS82 LMAIPLVFQIMFGILNGLYHYAVFEETLEKTIHEE 200 210 220 230 195 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:17:51 2016 done: Fri Nov 4 02:17:51 2016 Total Scan time: 1.520 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]