FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0121, 127 aa 1>>>pF1KE0121 127 - 127 aa - 127 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.4943+/-0.000333; mu= 14.6792+/- 0.020 mean_var=55.5367+/-11.424, 0's: 0 Z-trim(114.7): 6 B-trim: 0 in 0/54 Lambda= 0.172101 statistics sampled from 24663 (24667) to 24663 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.289), width: 16 Scan time: 4.640 The best scores are: opt bits E(85289) XP_006711329 (OMIM: 614737) PREDICTED: mitochondri ( 127) 860 221.1 3.9e-58 NP_056230 (OMIM: 614737) mitochondrial pyruvate ca ( 127) 860 221.1 3.9e-58 NP_001137146 (OMIM: 614737) mitochondrial pyruvate ( 127) 860 221.1 3.9e-58 NP_057182 (OMIM: 614738,614741) mitochondrial pyru ( 109) 146 43.7 8e-05 >>XP_006711329 (OMIM: 614737) PREDICTED: mitochondrial p (127 aa) initn: 860 init1: 860 opt: 860 Z-score: 1164.8 bits: 221.1 E(85289): 3.9e-58 Smith-Waterman score: 860; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KE0 MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE 70 80 90 100 110 120 pF1KE0 LKAKAHK ::::::: XP_006 LKAKAHK >>NP_056230 (OMIM: 614737) mitochondrial pyruvate carrie (127 aa) initn: 860 init1: 860 opt: 860 Z-score: 1164.8 bits: 221.1 E(85289): 3.9e-58 Smith-Waterman score: 860; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KE0 MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE 70 80 90 100 110 120 pF1KE0 LKAKAHK ::::::: NP_056 LKAKAHK >>NP_001137146 (OMIM: 614737) mitochondrial pyruvate car (127 aa) initn: 860 init1: 860 opt: 860 Z-score: 1164.8 bits: 221.1 E(85289): 3.9e-58 Smith-Waterman score: 860; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KE0 MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE 70 80 90 100 110 120 pF1KE0 LKAKAHK ::::::: NP_001 LKAKAHK >>NP_057182 (OMIM: 614738,614741) mitochondrial pyruvate (109 aa) initn: 144 init1: 144 opt: 146 Z-score: 207.6 bits: 43.7 E(85289): 8e-05 Smith-Waterman score: 146; 27.9% identity (59.3% similar) in 86 aa overlap (40-125:24-109) 10 20 30 40 50 60 pF1KE0 RATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLST .. ::.:. .::: :.. :: . : .: NP_057 MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISG 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 AQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK .. .: .. . :.. . :.:: ::: . .: : :. .... :.: NP_057 RMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIKHEMTKTASA 60 70 80 90 100 127 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:09:00 2016 done: Fri Nov 4 02:09:00 2016 Total Scan time: 4.640 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]