FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0124, 327 aa 1>>>pF1KE0124 327 - 327 aa - 327 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5309+/-0.000728; mu= 8.3988+/- 0.044 mean_var=148.8840+/-30.093, 0's: 0 Z-trim(114.3): 10 B-trim: 0 in 0/53 Lambda= 0.105111 statistics sampled from 14872 (14878) to 14872 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.457), width: 16 Scan time: 2.990 The best scores are: opt bits E(32554) CCDS11910.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 327) 2202 344.7 6e-95 CCDS45850.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 315) 1930 303.4 1.5e-82 CCDS45851.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 284) 1898 298.6 4e-81 CCDS58619.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 274) 1646 260.3 1.2e-69 CCDS1731.1 MAPRE3 gene_id:22924|Hs108|chr2 ( 281) 1142 183.9 1.3e-46 CCDS13208.1 MAPRE1 gene_id:22919|Hs108|chr20 ( 268) 1018 165.1 5.7e-41 >>CCDS11910.1 MAPRE2 gene_id:10982|Hs108|chr18 (327 aa) initn: 2202 init1: 2202 opt: 2202 Z-score: 1818.1 bits: 344.7 E(32554): 6e-95 Smith-Waterman score: 2202; 99.7% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KE0 MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 HDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSTKRASSSGSASKSDKDL :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS11 PPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYAS 250 260 270 280 290 300 310 320 pF1KE0 EEHEGHTEEPEAEEQAHEQQPPQQEEY ::::::::::::::::::::::::::: CCDS11 EEHEGHTEEPEAEEQAHEQQPPQQEEY 310 320 >>CCDS45850.1 MAPRE2 gene_id:10982|Hs108|chr18 (315 aa) initn: 1926 init1: 1926 opt: 1930 Z-score: 1595.5 bits: 303.4 E(32554): 1.5e-82 Smith-Waterman score: 1930; 91.2% identity (94.1% similar) in 320 aa overlap (8-327:1-315) 10 20 30 40 50 60 pF1KE0 MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSR .. : ... . : :.. : :: :::::::::::::::::::: CCDS45 MKQNRDQKCPVSQRNSSFQQPGRKPGCS-----SWGMAVNVYSTSITQETMSR 10 20 30 40 70 80 90 100 110 120 pF1KE0 HDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 LQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIP 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 PPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSTKRASSSGSASKSDKDL :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS45 PPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 ETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYAS 230 240 250 260 270 280 310 320 pF1KE0 EEHEGHTEEPEAEEQAHEQQPPQQEEY ::::::::::::::::::::::::::: CCDS45 EEHEGHTEEPEAEEQAHEQQPPQQEEY 290 300 310 >>CCDS45851.1 MAPRE2 gene_id:10982|Hs108|chr18 (284 aa) initn: 1898 init1: 1898 opt: 1898 Z-score: 1569.9 bits: 298.6 E(32554): 4e-81 Smith-Waterman score: 1898; 99.6% identity (100.0% similar) in 284 aa overlap (44-327:1-284) 20 30 40 50 60 70 pF1KE0 NNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL :::::::::::::::::::::::::::::: CCDS45 MAVNVYSTSITQETMSRHDIIAWVNDIVSL 10 20 30 80 90 100 110 120 130 pF1KE0 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 KSHHANSPTAGAAKSSPAAKPGSTPSRPSSTKRASSSGSASKSDKDLETQVIQLNEQVHS ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: CCDS45 KSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHS 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE0 LKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAE 220 230 240 250 260 270 320 pF1KE0 EQAHEQQPPQQEEY :::::::::::::: CCDS45 EQAHEQQPPQQEEY 280 >>CCDS58619.1 MAPRE2 gene_id:10982|Hs108|chr18 (274 aa) initn: 1646 init1: 1646 opt: 1646 Z-score: 1363.6 bits: 260.3 E(32554): 1.2e-69 Smith-Waterman score: 1646; 99.2% identity (100.0% similar) in 245 aa overlap (83-327:30-274) 60 70 80 90 100 110 pF1KE0 ITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEH .::::::::::::::::::::::::::::: CCDS58 MARTTTTSSRIITGPSFLSGSTQCAGSVPTGAAYCQFMDMLFPGCISLKKVKFQAKLEH 10 20 30 40 50 120 130 140 150 160 170 pF1KE0 EYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEA 60 70 80 90 100 110 180 190 200 210 220 230 pF1KE0 RQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSTKRASSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS58 RQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGS 120 130 140 150 160 170 240 250 260 270 280 290 pF1KE0 ASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQR 180 190 200 210 220 230 300 310 320 pF1KE0 LMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY ::::::::::::::::::::::::::::::::::: CCDS58 LMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY 240 250 260 270 >>CCDS1731.1 MAPRE3 gene_id:22924|Hs108|chr2 (281 aa) initn: 1173 init1: 880 opt: 1142 Z-score: 950.3 bits: 183.9 E(32554): 1.3e-46 Smith-Waterman score: 1142; 59.2% identity (83.0% similar) in 289 aa overlap (44-327:1-281) 20 30 40 50 60 70 pF1KE0 NNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL :::::::::.:.:..::::..::::: . : CCDS17 MAVNVYSTSVTSENLSRHDMLAWVNDSLHL 10 20 30 80 90 100 110 120 130 pF1KE0 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV ::::.::::::::::::::::::::. :.:::::::::::::::::.:::.::.:.:::. CCDS17 NYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKI 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK :::::::::.::::..::::::::.:::::::.:.:. ::::::. :::.::.:::: : CCDS17 IPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSK 100 110 120 130 140 150 200 210 220 230 240 pF1KE0 KSHHANSPTAGAAKSSPAA-KPGSTPSRPSSTKRA----SSSGSASKSDKDLETQVIQLN : . : ..::.. : .: .: :.. .. :: .. .. ..:...:: CCDS17 KLIGTAVPQ----RTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHETDAQILELN 160 170 180 190 200 250 260 270 280 290 300 pF1KE0 EQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTE .:. .:::...:.::::::::.:::.:::.:::: .::. ... .. ::::.:: . : CCDS17 QQLVDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPE 210 220 230 240 250 260 310 320 pF1KE0 EPEAEEQAHEQQPPQQEEY . : :: :.:. .:.:: CCDS17 DDEIEE--HQQE--DQDEY 270 280 >>CCDS13208.1 MAPRE1 gene_id:22919|Hs108|chr20 (268 aa) initn: 1050 init1: 784 opt: 1018 Z-score: 849.0 bits: 165.1 E(32554): 5.7e-41 Smith-Waterman score: 1021; 55.7% identity (79.1% similar) in 282 aa overlap (44-313:1-267) 20 30 40 50 60 70 pF1KE0 NNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL :::::::::.:....::::..::.:. ..: CCDS13 MAVNVYSTSVTSDNLSRHDMLAWINESLQL 10 20 30 80 90 100 110 120 130 pF1KE0 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV : ::.::::::::::::::::::: :.:::::::::::::::.:::.:::.::::.:::. CCDS13 NLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKLEHEYIQNFKILQAGFKRMGVDKI 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK :::.:::::.::::..:.::::::.:::::::.:::: :::::.. :. .: :: CCDS13 IPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDPVAARQGQETAVAPSLVAPALNKPK 100 110 120 130 140 150 200 210 220 230 240 pF1KE0 KSHHANSPTAGAAKSSPAAKPGSTPSRPSSTKRASSSGSAS----KSDKDL---ETQVIQ : : .. ...:.:: ::.:.... .:. ... . . .. . CCDS13 K---------------PLTSSSAAPQRPISTQRTAAAPKAGPGVVRKNPGVGNGDDEAAE 160 170 180 190 250 260 270 280 290 300 pF1KE0 LNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEE---- : .::. :::..: .::::::::::::.:::.:::. ::: ..::..:::::..: CCDS13 LMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVI 200 210 220 230 240 250 310 320 pF1KE0 -HEGHTEEPEAEEQAHEQQPPQQEEY :: .: . : CCDS13 PDEGGPQEEQEEY 260 327 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:01:00 2016 done: Fri Nov 4 02:01:01 2016 Total Scan time: 2.990 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]