FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0126, 125 aa 1>>>pF1KE0126 125 - 125 aa - 125 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2047+/-0.000755; mu= 10.6147+/- 0.046 mean_var=54.2482+/-10.828, 0's: 0 Z-trim(106.3): 20 B-trim: 0 in 0/52 Lambda= 0.174133 statistics sampled from 8896 (8905) to 8896 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.274), width: 16 Scan time: 1.310 The best scores are: opt bits E(32554) CCDS10960.1 MAP1LC3B gene_id:81631|Hs108|chr16 ( 125) 802 209.1 5.6e-55 CCDS41841.1 MAP1LC3B2 gene_id:643246|Hs108|chr12 ( 125) 791 206.4 3.8e-54 CCDS13238.1 MAP1LC3A gene_id:84557|Hs108|chr20 ( 121) 669 175.7 6.3e-45 CCDS13237.1 MAP1LC3A gene_id:84557|Hs108|chr20 ( 125) 599 158.1 1.3e-39 CCDS31074.1 MAP1LC3C gene_id:440738|Hs108|chr1 ( 147) 443 119.0 9.2e-28 CCDS10921.1 GABARAPL2 gene_id:11345|Hs108|chr16 ( 117) 307 84.8 1.4e-17 CCDS8620.1 GABARAPL1 gene_id:23710|Hs108|chr12 ( 117) 255 71.7 1.2e-13 CCDS11092.1 GABARAP gene_id:11337|Hs108|chr17 ( 117) 247 69.7 5e-13 >>CCDS10960.1 MAP1LC3B gene_id:81631|Hs108|chr16 (125 aa) initn: 802 init1: 802 opt: 802 Z-score: 1100.5 bits: 209.1 E(32554): 5.6e-55 Smith-Waterman score: 802; 100.0% identity (100.0% similar) in 125 aa overlap (1-125:1-125) 10 20 30 40 50 60 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG 70 80 90 100 110 120 pF1KE0 MKLSV ::::: CCDS10 MKLSV >>CCDS41841.1 MAP1LC3B2 gene_id:643246|Hs108|chr12 (125 aa) initn: 791 init1: 791 opt: 791 Z-score: 1085.5 bits: 206.4 E(32554): 3.8e-54 Smith-Waterman score: 791; 99.2% identity (99.2% similar) in 125 aa overlap (1-125:1-125) 10 20 30 40 50 60 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS41 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVCASQETFG 70 80 90 100 110 120 pF1KE0 MKLSV ::::: CCDS41 MKLSV >>CCDS13238.1 MAP1LC3A gene_id:84557|Hs108|chr20 (121 aa) initn: 669 init1: 669 opt: 669 Z-score: 920.1 bits: 175.7 E(32554): 6.3e-45 Smith-Waterman score: 669; 82.5% identity (95.0% similar) in 120 aa overlap (1-120:1-120) 10 20 30 40 50 60 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM :::.. :::::.: .: ..:. ::.:::.::::::::::::::::::::::::::::::: CCDS13 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG :::.:::::::::: .:::::::: ::::::::::...::.::::::::::::::::::: CCDS13 SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG 70 80 90 100 110 120 pF1KE0 MKLSV CCDS13 F >>CCDS13237.1 MAP1LC3A gene_id:84557|Hs108|chr20 (125 aa) initn: 599 init1: 599 opt: 599 Z-score: 824.8 bits: 158.1 E(32554): 1.3e-39 Smith-Waterman score: 599; 85.7% identity (96.2% similar) in 105 aa overlap (16-120:20-124) 10 20 30 40 50 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPD : ..:. ::.:::.::::::::::::::::::::::::::: CCDS13 MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 HVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQ :::::::.:::::::::: .:::::::: ::::::::::...::.::::::::::::::: CCDS13 HVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQ 70 80 90 100 110 120 120 pF1KE0 ETFGMKLSV :::: CCDS13 ETFGF >>CCDS31074.1 MAP1LC3C gene_id:440738|Hs108|chr1 (147 aa) initn: 443 init1: 443 opt: 443 Z-score: 611.9 bits: 119.0 E(32554): 9.2e-28 Smith-Waterman score: 443; 55.0% identity (84.2% similar) in 120 aa overlap (1-120:7-126) 10 20 30 40 50 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLV .:: . ::::... : :.: :: . :.::::..::: : :: :::::::: CCDS31 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 PDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYA :....:.....::: :. : :..::.::::..:.::.:. ..:.:.. ::::::.::.:: CCDS31 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA 70 80 90 100 110 120 120 pF1KE0 SQETFGMKLSV :::::: CCDS31 SQETFGCLESAAPRDGSSLEDRPCNPL 130 140 >>CCDS10921.1 GABARAPL2 gene_id:11345|Hs108|chr16 (117 aa) initn: 303 init1: 118 opt: 307 Z-score: 428.9 bits: 84.8 E(32554): 1.4e-17 Smith-Waterman score: 307; 39.5% identity (81.6% similar) in 114 aa overlap (7-120:5-116) 10 20 30 40 50 60 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM ::. ...:.: . :: ..: ..:::.:. .: .:. .:: :.:::. ... CCDS10 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSG-SQIVDIDKRKYLVPSDITV 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG .... :::.:.:: ...:.::.:. ... . : ....::.:::::::::..:....::: CCDS10 AQFMWIIRKRIQLPSEKAIFLFVD-KTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFG 60 70 80 90 100 110 pF1KE0 MKLSV CCDS10 F >>CCDS8620.1 GABARAPL1 gene_id:23710|Hs108|chr12 (117 aa) initn: 244 init1: 113 opt: 255 Z-score: 358.3 bits: 71.7 E(32554): 1.2e-13 Smith-Waterman score: 255; 32.5% identity (78.9% similar) in 114 aa overlap (7-120:5-116) 10 20 30 40 50 60 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM .:. . :: : .. . ::...: ..:::.:. . ..: ::: :.:::. ... CCDS86 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAP-KARVPDLDKRKYLVPSDLTV 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG ... .::.:..: ..:.:..:: ... .:. ....::....:: :::..:... ..: CCDS86 GQFYFLIRKRIHLRPEDALFFFVN-NTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYG 60 70 80 90 100 110 pF1KE0 MKLSV CCDS86 K >>CCDS11092.1 GABARAP gene_id:11337|Hs108|chr17 (117 aa) initn: 232 init1: 111 opt: 247 Z-score: 347.4 bits: 69.7 E(32554): 5e-13 Smith-Waterman score: 247; 31.3% identity (78.3% similar) in 115 aa overlap (7-121:5-117) 10 20 30 40 50 60 pF1KE0 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM .:... ::.: . . ::...: ..:::.:. . .. ::: :.:::. ... CCDS11 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAP-KARIGDLDKKKYLVPSDLTV 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG ... .::.:..: :..:.:..:: . . .:. ....:. ...:: :::..:... ..: CCDS11 GQFYFLIRKRIHLRAEDALFFFVN-NVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYG 60 70 80 90 100 110 pF1KE0 MKLSV . CCDS11 L 125 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:55:31 2016 done: Fri Nov 4 01:55:31 2016 Total Scan time: 1.310 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]