FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0129, 248 aa 1>>>pF1KE0129 248 - 248 aa - 248 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4522+/-0.000698; mu= 14.5057+/- 0.042 mean_var=67.2722+/-13.575, 0's: 0 Z-trim(110.4): 14 B-trim: 297 in 1/49 Lambda= 0.156371 statistics sampled from 11582 (11595) to 11582 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.356), width: 16 Scan time: 2.350 The best scores are: opt bits E(32554) CCDS76054.1 FAM58A gene_id:92002|Hs108|chrX ( 228) 1525 352.2 1.8e-97 CCDS45160.1 CCNK gene_id:8812|Hs108|chr14 ( 580) 344 86.0 6.2e-17 CCDS77847.1 CCNL1 gene_id:57018|Hs108|chr3 ( 428) 326 81.8 8e-16 CCDS3178.1 CCNL1 gene_id:57018|Hs108|chr3 ( 526) 326 81.9 9.5e-16 CCDS30557.1 CCNL2 gene_id:81669|Hs108|chr1 ( 520) 320 80.5 2.4e-15 CCDS2175.1 CCNT2 gene_id:905|Hs108|chr2 ( 663) 294 74.7 1.7e-13 CCDS2174.1 CCNT2 gene_id:905|Hs108|chr2 ( 730) 294 74.7 1.9e-13 >>CCDS76054.1 FAM58A gene_id:92002|Hs108|chrX (228 aa) initn: 1560 init1: 1520 opt: 1525 Z-score: 1863.6 bits: 352.2 E(32554): 1.8e-97 Smith-Waterman score: 1525; 96.9% identity (98.2% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KE0 MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 ETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWELRDS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 IVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQI :::::::::::::::::::::::::::::::::::::::... : : CCDS76 ALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQIYTMDTEIP 190 200 210 220 pF1KE0 YTMDTEIP >>CCDS45160.1 CCNK gene_id:8812|Hs108|chr14 (580 aa) initn: 307 init1: 176 opt: 344 Z-score: 417.5 bits: 86.0 E(32554): 6.2e-17 Smith-Waterman score: 345; 28.1% identity (64.3% similar) in 235 aa overlap (17-242:39-259) 10 20 30 40 pF1KE0 MEAPEGGGGGPAARGPEG-QPAPEARVHFRVARFIMEAGVKLGMRS :: .:: ::: . . ::::...:..::.. CCDS45 SPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHY 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 IPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSG .::. .:.:. .. . :. . ..::::::: . .:::... .: CCDS45 DTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN--- 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 EPLELDSRFWELRDS----IVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSW : .: .. :. .. : ..:....:... .::...::.: .:.. .... CCDS45 -----DVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKG--DKNKI 130 140 150 160 170 170 180 190 200 210 pF1KE0 QRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKP----W :. .. ::... :: .: :... . :::::.::: .. :. . . :: : CCDS45 QK--LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEI--QEWTSKPMYRRW 180 190 200 210 220 230 220 230 240 pF1KE0 WQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP :. : .:. ....: .....:. CCDS45 WEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPS 240 250 260 270 280 290 >>CCDS77847.1 CCNL1 gene_id:57018|Hs108|chr3 (428 aa) initn: 320 init1: 145 opt: 326 Z-score: 397.6 bits: 81.8 E(32554): 8e-16 Smith-Waterman score: 326; 28.9% identity (59.0% similar) in 239 aa overlap (11-242:66-290) 10 20 30 pF1KE0 MEAPEGGGGGPAARGPEGQPAPEARVHFRV--ARFIMEAG :. .: : ... .:. ..:. :: CCDS77 TTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLP-SETDLRILGCELIQAAG 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 VKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSN . : . .. .::. ...:.:: .. .. ..::. : ::.:.:: : ::.::: . CCDS77 ILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFH 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 RYFNPSGE----PLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQN . . :. :: ::. . . ...... : .:. : : : .:::: .. :: :. CCDS77 HLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLEC 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 WLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAE :. : ::: . :: . . .::: . :: : .::: .. . .:. CCDS77 ERNQTLVQ------TAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPT----- 220 230 240 250 260 220 230 240 pF1KE0 KP-WWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP .: :. .:. :. :..: . ...:: CCDS77 RPHWFLLFG--TTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLN 270 280 290 300 310 320 >>CCDS3178.1 CCNL1 gene_id:57018|Hs108|chr3 (526 aa) initn: 320 init1: 145 opt: 326 Z-score: 396.2 bits: 81.9 E(32554): 9.5e-16 Smith-Waterman score: 326; 28.9% identity (59.0% similar) in 239 aa overlap (11-242:66-290) 10 20 30 pF1KE0 MEAPEGGGGGPAARGPEGQPAPEARVHFRV--ARFIMEAG :. .: : ... .:. ..:. :: CCDS31 TTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLP-SETDLRILGCELIQAAG 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 VKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSN . : . .. .::. ...:.:: .. .. ..::. : ::.:.:: : ::.::: . CCDS31 ILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFH 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 RYFNPSGE----PLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQN . . :. :: ::. . . ...... : .:. : : : .:::: .. :: :. CCDS31 HLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLEC 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 WLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAE :. : ::: . :: . . .::: . :: : .::: .. . .:. CCDS31 ERNQTLVQ------TAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPT----- 220 230 240 250 260 220 230 240 pF1KE0 KP-WWQVFNDDLTKPIIDNIVSDLIQIYTMDTEIP .: :. .:. :. :..: . ...:: CCDS31 RPHWFLLFG--TTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLN 270 280 290 300 310 320 >>CCDS30557.1 CCNL2 gene_id:81669|Hs108|chr1 (520 aa) initn: 340 init1: 131 opt: 320 Z-score: 388.9 bits: 80.5 E(32554): 2.4e-15 Smith-Waterman score: 320; 29.9% identity (60.3% similar) in 214 aa overlap (33-241:84-284) 10 20 30 40 50 60 pF1KE0 APEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCET .:. ::. : . .. .::. .....:: CCDS30 LPDDKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTK 60 70 80 90 100 110 70 80 90 100 110 pF1KE0 NLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGE----PLELDSRFWELR .. .. ..:. ..::.:.:: : ::.::: .: . . :: ::. . .:. CCDS30 SFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLK 120 130 140 150 160 170 120 130 140 150 160 170 pF1KE0 DSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSY ..:.. : .:. : : : .:::: .. :: :. :.: : :.: . :: CCDS30 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQ------TSWNYMNDSL 180 190 200 210 220 180 190 200 210 220 230 pF1KE0 HGALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKP-WWQVFNDDLTKPIIDNIVSDL . . .::: . :: : .::: .. . .: ..: :. .:. :. :..: . CCDS30 RTDVFVRFQPESIACACIYLAARTLEIPLP-----NRPHWFLLFGA--TEEEIQEICLKI 230 240 250 260 270 280 240 pF1KE0 IQIYTMDTEIP .:.: CCDS30 LQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPK 290 300 310 320 330 340 >>CCDS2175.1 CCNT2 gene_id:905|Hs108|chr2 (663 aa) initn: 256 init1: 120 opt: 294 Z-score: 355.6 bits: 74.7 E(32554): 1.7e-13 Smith-Waterman score: 294; 26.4% identity (64.4% similar) in 216 aa overlap (29-240:39-243) 10 20 30 40 50 pF1KE0 MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKF ..: .:.: : .:.. .. : :: . .:.: CCDS21 SRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 FCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSR---FW . . .. .. .:. ....::.::::: . . .:.:.. ..: ::: ::.. . CCDS21 YMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPL-EPL-LDTKCDAYL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 ELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLR . . .: : .::..: :.....::: ... . : : : .: :.. . CCDS21 QQTQELVILETIMLQTLGFEITIEHPHTDVVKC-----TQLVRAS---KDLAQTSYFMAT 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 DSYH-GALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIV .: : ..::... :: . ..:: . . :.:. ... : ::. . .: ..:... CCDS21 NSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDG-KHWWEYVDPTVTLELLDELT 180 190 200 210 220 230 240 pF1KE0 SDLIQIYTMDTEIP ...:: CCDS21 HEFLQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPT 240 250 260 270 280 290 >>CCDS2174.1 CCNT2 gene_id:905|Hs108|chr2 (730 aa) initn: 256 init1: 120 opt: 294 Z-score: 355.0 bits: 74.7 E(32554): 1.9e-13 Smith-Waterman score: 294; 26.4% identity (64.4% similar) in 216 aa overlap (29-240:39-243) 10 20 30 40 50 pF1KE0 MEAPEGGGGGPAARGPEGQPAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKF ..: .:.: : .:.. .. : :: . .:.: CCDS21 SRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 FCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSR---FW . . .. .. .:. ....::.::::: . . .:.:.. ..: ::: ::.. . CCDS21 YMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPL-EPL-LDTKCDAYL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 ELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLR . . .: : .::..: :.....::: ... . : : : .: :.. . CCDS21 QQTQELVILETIMLQTLGFEITIEHPHTDVVKC-----TQLVRAS---KDLAQTSYFMAT 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 DSYH-GALCLRFQAQHIAVAVLYLALQVYGVEVPAEVEAEKPWWQVFNDDLTKPIIDNIV .: : ..::... :: . ..:: . . :.:. ... : ::. . .: ..:... CCDS21 NSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDG-KHWWEYVDPTVTLELLDELT 180 190 200 210 220 230 240 pF1KE0 SDLIQIYTMDTEIP ...:: CCDS21 HEFLQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPT 240 250 260 270 280 290 248 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:47:32 2016 done: Fri Nov 4 01:47:33 2016 Total Scan time: 2.350 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]