FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0131, 183 aa 1>>>pF1KE0131 183 - 183 aa - 183 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8878+/-0.00034; mu= 10.3121+/- 0.021 mean_var=74.8118+/-15.412, 0's: 0 Z-trim(116.2): 49 B-trim: 917 in 2/55 Lambda= 0.148282 statistics sampled from 27072 (27121) to 27072 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.318), width: 16 Scan time: 5.740 The best scores are: opt bits E(85289) NP_149076 (OMIM: 300450) fetal and adult testis-ex ( 183) 1209 267.4 9.2e-72 XP_005246742 (OMIM: 614785,617086) PREDICTED: mito ( 289) 142 39.2 0.0071 NP_001263991 (OMIM: 614785,617086) mitochondrial f ( 291) 142 39.2 0.0071 XP_006712701 (OMIM: 614785,617086) PREDICTED: mito ( 291) 142 39.2 0.0071 XP_005246739 (OMIM: 614785,617086) PREDICTED: mito ( 317) 142 39.2 0.0077 XP_016860001 (OMIM: 614785,617086) PREDICTED: mito ( 317) 142 39.2 0.0077 XP_016860004 (OMIM: 614785,617086) PREDICTED: mito ( 243) 140 38.8 0.0082 NP_001263992 (OMIM: 614785,617086) mitochondrial f ( 243) 140 38.8 0.0082 XP_005246743 (OMIM: 614785,617086) PREDICTED: mito ( 269) 140 38.8 0.009 >>NP_149076 (OMIM: 300450) fetal and adult testis-expres (183 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1409.3 bits: 267.4 E(85289): 9.2e-72 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KE0 MAGGPPNTKAEMEMSLAEELNHGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MAGGPPNTKAEMEMSLAEELNHGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SASAKRVWNMTATRPKKMGSQLPKPRMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 SASAKRVWNMTATRPKKMGSQLPKPRMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VAQTSLEEFNVLEMEVMRRQLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 VAQTSLEEFNVLEMEVMRRQLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLW 130 140 150 160 170 180 pF1KE0 MNQ ::: NP_149 MNQ >>XP_005246742 (OMIM: 614785,617086) PREDICTED: mitochon (289 aa) initn: 165 init1: 133 opt: 142 Z-score: 172.6 bits: 39.2 E(85289): 0.0071 Smith-Waterman score: 142; 20.9% identity (56.1% similar) in 148 aa overlap (36-180:143-286) 10 20 30 40 50 60 pF1KE0 PNTKAEMEMSLAEELNHGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAK :. .: .: :.... ..:.. . XP_005 LKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQNGQ-LVRND 120 130 140 150 160 170 70 80 90 100 110 120 pF1KE0 RVWNMTATRPKKMGSQLPKPRMLRESG---HGDAHLQEYAGNFQGIRFHYDRNPGTDAVA .:. . . :.. :.. : : .: . . ...:. . . :.. XP_005 SLWHRSDSAPRNKISRFQAPISAPEYTPVLRGGSAAATSNPHHDNVRYGIS---NIDTTI 180 190 200 210 220 130 140 150 160 170 180 pF1KE0 QTSLEEFNVLEMEVMRRQLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMN . . ....:.. .:::. .::::. :::.. .:: .. .. :. . : ::: XP_005 EGTSDDLTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFR 230 240 250 260 270 280 pF1KE0 Q XP_005 R >>NP_001263991 (OMIM: 614785,617086) mitochondrial fissi (291 aa) initn: 149 init1: 133 opt: 142 Z-score: 172.6 bits: 39.2 E(85289): 0.0071 Smith-Waterman score: 142; 22.2% identity (55.7% similar) in 185 aa overlap (5-180:109-288) 10 20 30 pF1KE0 MAGGPPNTKAEMEMSLAEELNHGRQ-GEN---QE ::.: . :. . .:.. :. .:: :. NP_001 STPFKPLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQN 80 90 100 110 120 130 40 50 60 70 80 pF1KE0 -HLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ----LPKP .:: . . : ... . : . .:. .::. . .. . .. .: : . NP_001 GQLVRNDSLVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQQILDVLDEN 140 150 160 170 180 190 90 100 110 120 130 140 pF1KE0 RMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVN : : .: . . ...:. . . :.. . . ....:.. .:::. .: NP_001 R--RPVLRGGSAAATSNPHHDNVRYGIS---NIDTTIEGTSDDLTVVDAASLRRQIIKLN 200 210 220 230 240 250 150 160 170 180 pF1KE0 RRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :::. :::.. .:: .. .. :. . : ::: NP_001 RRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 260 270 280 290 >>XP_006712701 (OMIM: 614785,617086) PREDICTED: mitochon (291 aa) initn: 149 init1: 133 opt: 142 Z-score: 172.6 bits: 39.2 E(85289): 0.0071 Smith-Waterman score: 142; 22.2% identity (55.7% similar) in 185 aa overlap (5-180:109-288) 10 20 30 pF1KE0 MAGGPPNTKAEMEMSLAEELNHGRQ-GEN---QE ::.: . :. . .:.. :. .:: :. XP_006 STPFKPLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQN 80 90 100 110 120 130 40 50 60 70 80 pF1KE0 -HLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ----LPKP .:: . . : ... . : . .:. .::. . .. . .. .: : . XP_006 GQLVRNDSLVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQQILDVLDEN 140 150 160 170 180 190 90 100 110 120 130 140 pF1KE0 RMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVN : : .: . . ...:. . . :.. . . ....:.. .:::. .: XP_006 R--RPVLRGGSAAATSNPHHDNVRYGIS---NIDTTIEGTSDDLTVVDAASLRRQIIKLN 200 210 220 230 240 250 150 160 170 180 pF1KE0 RRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :::. :::.. .:: .. .. :. . : ::: XP_006 RRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 260 270 280 290 >>XP_005246739 (OMIM: 614785,617086) PREDICTED: mitochon (317 aa) initn: 133 init1: 133 opt: 142 Z-score: 172.0 bits: 39.2 E(85289): 0.0077 Smith-Waterman score: 142; 22.2% identity (55.7% similar) in 185 aa overlap (5-180:135-314) 10 20 30 pF1KE0 MAGGPPNTKAEMEMSLAEELNHGRQ-GEN---QE ::.: . :. . .:.. :. .:: :. XP_005 STPFKPLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQN 110 120 130 140 150 160 40 50 60 70 80 pF1KE0 -HLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ----LPKP .:: . . : ... . : . .:. .::. . .. . .. .: : . XP_005 GQLVRNDSLVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQQILDVLDEN 170 180 190 200 210 220 90 100 110 120 130 140 pF1KE0 RMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVN : : .: . . ...:. . . :.. . . ....:.. .:::. .: XP_005 R--RPVLRGGSAAATSNPHHDNVRYGIS---NIDTTIEGTSDDLTVVDAASLRRQIIKLN 230 240 250 260 270 150 160 170 180 pF1KE0 RRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :::. :::.. .:: .. .. :. . : ::: XP_005 RRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 280 290 300 310 >>XP_016860001 (OMIM: 614785,617086) PREDICTED: mitochon (317 aa) initn: 133 init1: 133 opt: 142 Z-score: 172.0 bits: 39.2 E(85289): 0.0077 Smith-Waterman score: 142; 22.2% identity (55.7% similar) in 185 aa overlap (5-180:135-314) 10 20 30 pF1KE0 MAGGPPNTKAEMEMSLAEELNHGRQ-GEN---QE ::.: . :. . .:.. :. .:: :. XP_016 STPFKPLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQN 110 120 130 140 150 160 40 50 60 70 80 pF1KE0 -HLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ----LPKP .:: . . : ... . : . .:. .::. . .. . .. .: : . XP_016 GQLVRNDSLVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQQILDVLDEN 170 180 190 200 210 220 90 100 110 120 130 140 pF1KE0 RMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVN : : .: . . ...:. . . :.. . . ....:.. .:::. .: XP_016 R--RPVLRGGSAAATSNPHHDNVRYGIS---NIDTTIEGTSDDLTVVDAASLRRQIIKLN 230 240 250 260 270 150 160 170 180 pF1KE0 RRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :::. :::.. .:: .. .. :. . : ::: XP_016 RRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 280 290 300 310 >>XP_016860004 (OMIM: 614785,617086) PREDICTED: mitochon (243 aa) initn: 164 init1: 133 opt: 140 Z-score: 171.5 bits: 38.8 E(85289): 0.0082 Smith-Waterman score: 140; 23.7% identity (61.8% similar) in 131 aa overlap (52-180:114-240) 30 40 50 60 70 80 pF1KE0 HGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ :. : .:.: . .: . .:.: ...: XP_016 PLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVR---QNGQ 90 100 110 120 130 140 90 100 110 120 130 pF1KE0 LPKPRML--RESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRR : . : : .. ..... . ... .. : . . :.. . . ....:.. .:: XP_016 LVRNDSLWHRSDSAPRNKISRFQAPISAPEYTYGIS-NIDTTIEGTSDDLTVVDAASLRR 150 160 170 180 190 140 150 160 170 180 pF1KE0 QLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :. .::::. :::.. .:: .. .. :. . : ::: XP_016 QIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 200 210 220 230 240 >>NP_001263992 (OMIM: 614785,617086) mitochondrial fissi (243 aa) initn: 164 init1: 133 opt: 140 Z-score: 171.5 bits: 38.8 E(85289): 0.0082 Smith-Waterman score: 140; 23.7% identity (61.8% similar) in 131 aa overlap (52-180:114-240) 30 40 50 60 70 80 pF1KE0 HGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ :. : .:.: . .: . .:.: ...: NP_001 PLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVR---QNGQ 90 100 110 120 130 140 90 100 110 120 130 pF1KE0 LPKPRML--RESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRR : . : : .. ..... . ... .. : . . :.. . . ....:.. .:: NP_001 LVRNDSLWHRSDSAPRNKISRFQAPISAPEYTYGIS-NIDTTIEGTSDDLTVVDAASLRR 150 160 170 180 190 140 150 160 170 180 pF1KE0 QLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :. .::::. :::.. .:: .. .. :. . : ::: NP_001 QIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 200 210 220 230 240 >>XP_005246743 (OMIM: 614785,617086) PREDICTED: mitochon (269 aa) initn: 149 init1: 133 opt: 140 Z-score: 170.8 bits: 38.8 E(85289): 0.009 Smith-Waterman score: 140; 23.7% identity (61.8% similar) in 131 aa overlap (52-180:140-266) 30 40 50 60 70 80 pF1KE0 HGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQ :. : .:.: . .: . .:.: ...: XP_005 PLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVR---QNGQ 110 120 130 140 150 160 90 100 110 120 130 pF1KE0 LPKPRML--RESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRR : . : : .. ..... . ... .. : . . :.. . . ....:.. .:: XP_005 LVRNDSLWHRSDSAPRNKISRFQAPISAPEYTYGIS-NIDTTIEGTSDDLTVVDAASLRR 170 180 190 200 210 220 140 150 160 170 180 pF1KE0 QLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ :. .::::. :::.. .:: .. .. :. . : ::: XP_005 QIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR 230 240 250 260 183 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:27:58 2016 done: Fri Nov 4 01:27:58 2016 Total Scan time: 5.740 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]