FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0134, 214 aa 1>>>pF1KE0134 214 - 214 aa - 214 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8060+/-0.000352; mu= 16.4592+/- 0.022 mean_var=61.5132+/-12.766, 0's: 0 Z-trim(114.1): 7 B-trim: 1190 in 1/50 Lambda= 0.163527 statistics sampled from 23747 (23754) to 23747 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.279), width: 16 Scan time: 4.820 The best scores are: opt bits E(85289) NP_006004 (OMIM: 300847,312173) 60S ribosomal prot ( 214) 1494 360.7 1.1e-99 NP_001290553 (OMIM: 300847,312173) 60S ribosomal p ( 214) 1494 360.7 1.1e-99 NP_001290554 (OMIM: 300847,312173) 60S ribosomal p ( 214) 1494 360.7 1.1e-99 NP_001243509 (OMIM: 300847,312173) 60S ribosomal p ( 178) 1037 252.8 2.6e-67 NP_001243506 (OMIM: 300847,312173) 60S ribosomal p ( 216) 789 194.3 1.2e-49 NP_001290555 (OMIM: 300847,312173) 60S ribosomal p ( 145) 785 193.3 1.7e-49 >>NP_006004 (OMIM: 300847,312173) 60S ribosomal protein (214 aa) initn: 1494 init1: 1494 opt: 1494 Z-score: 1911.0 bits: 360.7 E(85289): 1.1e-99 Smith-Waterman score: 1494; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214) 10 20 30 40 50 60 pF1KE0 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE 130 140 150 160 170 180 190 200 210 pF1KE0 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS :::::::::::::::::::::::::::::::::: NP_006 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS 190 200 210 >>NP_001290553 (OMIM: 300847,312173) 60S ribosomal prote (214 aa) initn: 1494 init1: 1494 opt: 1494 Z-score: 1911.0 bits: 360.7 E(85289): 1.1e-99 Smith-Waterman score: 1494; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214) 10 20 30 40 50 60 pF1KE0 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE 130 140 150 160 170 180 190 200 210 pF1KE0 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS :::::::::::::::::::::::::::::::::: NP_001 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS 190 200 210 >>NP_001290554 (OMIM: 300847,312173) 60S ribosomal prote (214 aa) initn: 1494 init1: 1494 opt: 1494 Z-score: 1911.0 bits: 360.7 E(85289): 1.1e-99 Smith-Waterman score: 1494; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214) 10 20 30 40 50 60 pF1KE0 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE 130 140 150 160 170 180 190 200 210 pF1KE0 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS :::::::::::::::::::::::::::::::::: NP_001 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS 190 200 210 >>NP_001243509 (OMIM: 300847,312173) 60S ribosomal prote (178 aa) initn: 1239 init1: 1037 opt: 1037 Z-score: 1329.4 bits: 252.8 E(85289): 2.6e-67 Smith-Waterman score: 1171; 83.2% identity (83.2% similar) in 214 aa overlap (1-214:1-178) 10 20 30 40 50 60 pF1KE0 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL ::::::::::::::::::::::::::: NP_001 MGRRPARCYRYCKNKPYPKSRFCRGVP--------------------------------- 10 20 70 80 90 100 110 120 pF1KE0 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---ALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG 30 40 50 60 70 80 130 140 150 160 170 180 pF1KE0 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE 90 100 110 120 130 140 190 200 210 pF1KE0 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS :::::::::::::::::::::::::::::::::: NP_001 FEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS 150 160 170 >>NP_001243506 (OMIM: 300847,312173) 60S ribosomal prote (216 aa) initn: 789 init1: 789 opt: 789 Z-score: 1012.0 bits: 194.3 E(85289): 1.2e-49 Smith-Waterman score: 789; 94.9% identity (95.8% similar) in 118 aa overlap (1-118:1-118) 10 20 30 40 50 60 pF1KE0 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG :::::::::::::::::::::::::::::::::::::::::::::::::: . :: NP_001 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRSTSQRSGASP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE NP_001 SSMLMNLKTWWLKSGSSQMAVGSSTSPVVALWTSGGPCTHEGFQCAAPLLILTNKFYFLS 130 140 150 160 170 180 >>NP_001290555 (OMIM: 300847,312173) 60S ribosomal prote (145 aa) initn: 783 init1: 783 opt: 785 Z-score: 1009.4 bits: 193.3 E(85289): 1.7e-49 Smith-Waterman score: 785; 90.5% identity (92.9% similar) in 126 aa overlap (1-125:1-126) 10 20 30 40 50 60 pF1KE0 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG :::::::::::::::::::::::::::::::::::::::::::::::::: . : : NP_001 SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRHARCLWKAPG 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 K-PQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNAD . ::. NP_001 HCGQGSHWPSYHVHPHQAAEQGACD 130 140 214 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:12:43 2016 done: Fri Nov 4 01:12:43 2016 Total Scan time: 4.820 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]