FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0135, 339 aa
1>>>pF1KE0135 339 - 339 aa - 339 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.2778+/-0.000512; mu= -10.6962+/- 0.032
mean_var=370.5676+/-75.640, 0's: 0 Z-trim(118.6): 3 B-trim: 527 in 1/56
Lambda= 0.066626
statistics sampled from 31758 (31761) to 31758 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.372), width: 16
Scan time: 7.840
The best scores are: opt bits E(85289)
NP_004690 (OMIM: 300453) protein FAM50A [Homo sapi ( 339) 2198 225.1 1.8e-58
NP_036267 (OMIM: 614686) protein FAM50B [Homo sapi ( 325) 1158 125.1 2.1e-28
XP_016866218 (OMIM: 614686) PREDICTED: protein FAM ( 325) 1158 125.1 2.1e-28
>>NP_004690 (OMIM: 300453) protein FAM50A [Homo sapiens] (339 aa)
initn: 2198 init1: 2198 opt: 2198 Z-score: 1170.9 bits: 225.1 E(85289): 1.8e-58
Smith-Waterman score: 2198; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339)
10 20 30 40 50 60
pF1KE0 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE
250 260 270 280 290 300
310 320 330
pF1KE0 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
:::::::::::::::::::::::::::::::::::::::
NP_004 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
310 320 330
>>NP_036267 (OMIM: 614686) protein FAM50B [Homo sapiens] (325 aa)
initn: 1726 init1: 1142 opt: 1158 Z-score: 630.9 bits: 125.1 E(85289): 2.1e-28
Smith-Waterman score: 1700; 74.3% identity (90.3% similar) in 339 aa overlap (1-339:1-325)
10 20 30 40 50 60
pF1KE0 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL
::::::. ::::::::.::::.:::::: .:::::::.:.::..::.::::::::::::
NP_036 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL
:::::::::::::::.:::::.:::.::::... .: ... :. ::.:...: ::::: :
NP_036 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR
::.:.. .. .. : . . .:::::::::::::::::::::::::
NP_036 SFALDDLDDQADAAE--------------ARRAGNLGKNPDVDTSFLPDRDREEEENRLR
130 140 150 160
190 200 210 220 230 240
pF1KE0 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE
:::::::::..::.:.::.:.::::::::::::::..:::::.::::.:::. ::::: :
NP_036 EELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE
::::::::::.::::::.::.:.:::::...:::::::::.::::::::::::::.::::
NP_036 LRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDE
230 240 250 260 270 280
310 320 330
pF1KE0 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
::::::::::::::::::::::::: :::::::::::::
NP_036 SHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR
290 300 310 320
>>XP_016866218 (OMIM: 614686) PREDICTED: protein FAM50B (325 aa)
initn: 1726 init1: 1142 opt: 1158 Z-score: 630.9 bits: 125.1 E(85289): 2.1e-28
Smith-Waterman score: 1700; 74.3% identity (90.3% similar) in 339 aa overlap (1-339:1-325)
10 20 30 40 50 60
pF1KE0 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL
::::::. ::::::::.::::.:::::: .:::::::.:.::..::.::::::::::::
XP_016 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL
:::::::::::::::.:::::.:::.::::... .: ... :. ::.:...: ::::: :
XP_016 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR
::.:.. .. .. : . . .:::::::::::::::::::::::::
XP_016 SFALDDLDDQADAAE--------------ARRAGNLGKNPDVDTSFLPDRDREEEENRLR
130 140 150 160
190 200 210 220 230 240
pF1KE0 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE
:::::::::..::.:.::.:.::::::::::::::..:::::.::::.:::. ::::: :
XP_016 EELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE
::::::::::.::::::.::.:.:::::...:::::::::.::::::::::::::.::::
XP_016 LRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDE
230 240 250 260 270 280
310 320 330
pF1KE0 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
::::::::::::::::::::::::: :::::::::::::
XP_016 SHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR
290 300 310 320
339 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:09:57 2016 done: Fri Nov 4 01:09:58 2016
Total Scan time: 7.840 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]