FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0136, 302 aa 1>>>pF1KE0136 302 - 302 aa - 302 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3451+/-0.000405; mu= 14.9569+/- 0.025 mean_var=59.9126+/-12.026, 0's: 0 Z-trim(111.4): 35 B-trim: 41 in 1/50 Lambda= 0.165697 statistics sampled from 19934 (19969) to 19934 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.234), width: 16 Scan time: 6.840 The best scores are: opt bits E(85289) XP_016884821 (OMIM: 300081) PREDICTED: deoxyribonu ( 302) 1956 476.1 3.7e-134 NP_001009932 (OMIM: 300081) deoxyribonuclease-1-li ( 302) 1956 476.1 3.7e-134 XP_005277886 (OMIM: 300081) PREDICTED: deoxyribonu ( 302) 1956 476.1 3.7e-134 NP_006721 (OMIM: 300081) deoxyribonuclease-1-like ( 302) 1956 476.1 3.7e-134 XP_011529424 (OMIM: 300081) PREDICTED: deoxyribonu ( 302) 1956 476.1 3.7e-134 NP_001290549 (OMIM: 300081) deoxyribonuclease-1-li ( 302) 1956 476.1 3.7e-134 NP_001009934 (OMIM: 300081) deoxyribonuclease-1-li ( 302) 1956 476.1 3.7e-134 NP_001009933 (OMIM: 300081) deoxyribonuclease-1-li ( 302) 1956 476.1 3.7e-134 NP_004935 (OMIM: 602244,614420) deoxyribonuclease ( 305) 782 195.5 1.1e-49 NP_005214 (OMIM: 125505,152700) deoxyribonuclease- ( 282) 626 158.2 1.8e-38 XP_011520695 (OMIM: 125505,152700) PREDICTED: deox ( 282) 626 158.2 1.8e-38 XP_016878488 (OMIM: 125505,152700) PREDICTED: deox ( 282) 626 158.2 1.8e-38 XP_005255205 (OMIM: 125505,152700) PREDICTED: deox ( 276) 556 141.4 1.9e-33 XP_016878485 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 XP_016878483 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 XP_016878487 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 XP_016878482 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 XP_016878481 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 XP_016878484 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 XP_016878486 (OMIM: 125505,152700) PREDICTED: deox ( 304) 556 141.4 2.1e-33 NP_001243489 (OMIM: 602244,614420) deoxyribonuclea ( 275) 545 138.8 1.2e-32 XP_006720917 (OMIM: 125505,152700) PREDICTED: deox ( 213) 499 127.8 1.9e-29 XP_016878491 (OMIM: 125505,152700) PREDICTED: deox ( 235) 429 111.0 2.3e-24 XP_016878490 (OMIM: 125505,152700) PREDICTED: deox ( 235) 429 111.0 2.3e-24 NP_001288609 (OMIM: 602622) deoxyribonuclease-1-li ( 299) 403 104.9 2.1e-22 NP_001365 (OMIM: 602622) deoxyribonuclease-1-like ( 299) 403 104.9 2.1e-22 XP_011520701 (OMIM: 602622) PREDICTED: deoxyribonu ( 390) 403 104.9 2.6e-22 XP_016878496 (OMIM: 125505,152700) PREDICTED: deox ( 184) 258 70.1 3.7e-12 XP_016878494 (OMIM: 125505,152700) PREDICTED: deox ( 187) 218 60.6 2.8e-09 XP_016878493 (OMIM: 125505,152700) PREDICTED: deox ( 187) 218 60.6 2.8e-09 XP_016878492 (OMIM: 125505,152700) PREDICTED: deox ( 187) 218 60.6 2.8e-09 XP_016878495 (OMIM: 125505,152700) PREDICTED: deox ( 187) 218 60.6 2.8e-09 XP_016878489 (OMIM: 125505,152700) PREDICTED: deox ( 279) 218 60.6 4e-09 >>XP_016884821 (OMIM: 300081) PREDICTED: deoxyribonuclea (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_016 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: XP_016 AA >>NP_001009932 (OMIM: 300081) deoxyribonuclease-1-like 1 (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_001 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: NP_001 AA >>XP_005277886 (OMIM: 300081) PREDICTED: deoxyribonuclea (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_005 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: XP_005 AA >>NP_006721 (OMIM: 300081) deoxyribonuclease-1-like 1 pr (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_006 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: NP_006 AA >>XP_011529424 (OMIM: 300081) PREDICTED: deoxyribonuclea (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_011 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: XP_011 AA >>NP_001290549 (OMIM: 300081) deoxyribonuclease-1-like 1 (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_001 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: NP_001 AA >>NP_001009934 (OMIM: 300081) deoxyribonuclease-1-like 1 (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_001 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: NP_001 AA >>NP_001009933 (OMIM: 300081) deoxyribonuclease-1-like 1 (302 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2529.6 bits: 476.1 E(85289): 3.7e-134 Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLPSLLSPQLCP :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_001 HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCP 250 260 270 280 290 300 pF1KE0 AA :: NP_001 AA >>NP_004935 (OMIM: 602244,614420) deoxyribonuclease gamm (305 aa) initn: 701 init1: 406 opt: 782 Z-score: 1012.8 bits: 195.5 E(85289): 1.1e-49 Smith-Waterman score: 782; 41.3% identity (76.7% similar) in 288 aa overlap (7-287:9-296) 10 20 30 40 50 pF1KE0 MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEV ::.:. ..: :.:::.::.. . .: ...::..:... ::::....:. NP_004 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 VDSSGSAIPLLLRELNRFDGSG-PYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYN ::.. :.:...::: . : :. . : .:::.:: : :...:. . ..: :: :. NP_004 KDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 D-ED---DVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQ : .: :::.:::::. :. : ... ..:..::::::.. ::.. : .:. .:...:. NP_004 DYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 SKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHG ... :..::::: :. . :: ...:::.: : :.:.: :::::. ::.:.:::.::.: NP_004 AENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 ERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLP .. : . .. ..::: ...:::::::..:::.::: .:. :.: . . :.:. NP_004 QEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKT 250 260 270 280 290 300 300 pF1KE0 SLLSPQLCPAA NP_004 KSKRS >>NP_005214 (OMIM: 125505,152700) deoxyribonuclease-1 pr (282 aa) initn: 562 init1: 275 opt: 626 Z-score: 811.8 bits: 158.2 E(85289): 1.8e-38 Smith-Waterman score: 626; 39.1% identity (68.8% similar) in 276 aa overlap (6-273:9-282) 10 20 30 40 50 pF1KE0 MHYPTALLFLI-LANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQ ::: : : .:: ...: ::: : . .:.. ... .:.::.: :: ..: NP_005 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 EVVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVY :: :: .:. :: .::. :. : . : :::..: : :.. :: ......:: : NP_005 EVRDSHLTAVGKLLDNLNQ-DAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYY 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 NDE-----DDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQH .: .:.: ::: ...: . . ...::::..: . :..:::::.:.:... NP_005 DDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 WQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVL : .::.:.::::: :. . .. ....: : : :.:.: :. :::. . :::.:::.:. NP_005 WGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTA-TPTHCAYDRIVV 180 190 200 210 220 230 240 250 260 270 280 pF1KE0 HGERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLL : :. . .: :.: ... :... : ::::::::: :: NP_005 AGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK 240 250 260 270 280 290 300 pF1KE0 LPSLLSPQLCPAA 302 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:06:20 2016 done: Fri Nov 4 01:06:21 2016 Total Scan time: 6.840 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]