Result of FASTA (omim) for
pF1KE0137
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0137, 172 aa
1>>>pF1KE0137 172 - 172 aa - 172 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0737+/-0.000408; mu= 10.8202+/- 0.026
mean_var=141.3394+/-29.002, 0's: 0 Z-trim(116.7): 161 B-trim: 729 in 2/51
Lambda= 0.107880
statistics sampled from 27769 (28008) to 27769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.328), width: 16
Scan time: 5.270
The best scores are: opt bits E(85289)
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 1087 179.9 1.7e-45
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 961 160.3 1.4e-39
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 601 104.3 1e-22
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191) 570 99.5 3.1e-21
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 496 87.9 7.7e-18
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 496 87.9 7.7e-18
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 496 87.9 7.7e-18
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 496 87.9 7.7e-18
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 496 87.9 7.8e-18
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 496 88.0 9.3e-18
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 478 85.1 5.4e-17
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 402 73.3 2.1e-13
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 387 70.9 9.7e-13
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 374 68.7 3.4e-12
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 374 68.7 3.4e-12
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 374 68.7 3.4e-12
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 374 68.7 3.4e-12
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 374 68.7 3.4e-12
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 374 68.7 3.4e-12
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 374 68.7 3.4e-12
NP_001284697 (OMIM: 602907) centrin-3 isoform 3 [H ( 153) 375 69.0 3.7e-12
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 365 67.5 1.1e-11
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146) 352 65.4 4.3e-11
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 314 59.6 2.8e-09
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 312 59.3 3.6e-09
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 310 59.0 4.6e-09
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 310 59.1 4.9e-09
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 312 59.6 4.9e-09
NP_112482 (OMIM: 605563) calcium-binding protein 1 ( 227) 293 56.5 3.3e-08
NP_004267 (OMIM: 605563) calcium-binding protein 1 ( 167) 291 56.0 3.4e-08
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 291 56.0 3.4e-08
NP_001028849 (OMIM: 605563) calcium-binding protei ( 370) 289 56.1 7e-08
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 285 55.2 7.7e-08
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226) 285 55.2 7.8e-08
XP_011543485 (OMIM: 608965,610427) PREDICTED: calc ( 170) 281 54.5 1e-07
NP_001287825 (OMIM: 608965,610427) calcium-binding ( 170) 281 54.5 1e-07
XP_016873514 (OMIM: 608965,610427) PREDICTED: calc ( 170) 281 54.5 1e-07
NP_001287824 (OMIM: 608965,610427) calcium-binding ( 170) 281 54.5 1e-07
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 280 54.3 1.1e-07
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 280 54.3 1.1e-07
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 280 54.3 1.1e-07
NP_660201 (OMIM: 608965,610427) calcium-binding pr ( 275) 281 54.7 1.4e-07
XP_011543483 (OMIM: 608965,610427) PREDICTED: calc ( 295) 281 54.7 1.4e-07
XP_016875727 (OMIM: 605563) PREDICTED: calcium-bin ( 262) 272 53.3 3.5e-07
XP_016875728 (OMIM: 605563) PREDICTED: calcium-bin ( 202) 270 52.8 3.7e-07
XP_016863734 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 266 52.1 5.1e-07
NP_002468 (OMIM: 160782) myosin light chain 5 [Hom ( 173) 266 52.1 5.1e-07
XP_016863735 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 266 52.1 5.1e-07
XP_016875724 (OMIM: 605563) PREDICTED: calcium-bin ( 405) 268 52.9 7.2e-07
XP_006713949 (OMIM: 160782) PREDICTED: myosin ligh ( 328) 266 52.5 7.8e-07
>>NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] (172 aa)
initn: 1087 init1: 1087 opt: 1087 Z-score: 937.6 bits: 179.9 E(85289): 1.7e-45
Smith-Waterman score: 1087; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
130 140 150 160 170
>>NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] (172 aa)
initn: 961 init1: 961 opt: 961 Z-score: 831.6 bits: 160.3 E(85289): 1.4e-39
Smith-Waterman score: 961; 83.7% identity (98.8% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
:::.::: . ::..:.....:::::::.::::.::::::::.::.::::.::::::::::
NP_004 MASGFKKPSAASTGQKRKVAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
::::.:::.::::::.:.:::::..:.:::.:::::::::::::::::::.:::::::::
NP_004 GFEPRKEEMKKMISEVDREGTGKISFNDFLAVMTQKMSEKDTKEEILKAFRLFDDDETGK
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
::::::::::.::::::::::::::::::::::::::.:.::::::::::::
NP_004 ISFKNLKRVANELGENLTDEELQEMIDEADRDGDGEVNEEEFLRIMKKTSLY
130 140 150 160 170
>>NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo sap (167 aa)
initn: 595 init1: 595 opt: 601 Z-score: 529.0 bits: 104.3 E(85289): 1e-22
Smith-Waterman score: 601; 54.2% identity (84.9% similar) in 166 aa overlap (1-166:1-163)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
:. ... ......::. . ::.:::::::..::.:::.: .:: .:::::::::
NP_004 MSLALRSELVVDKTKRKK---RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRAL
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
::. :: .. :.... :.:.:::..: :: :.:. . :.: .:::::::::::::..::
NP_004 GFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGK
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
::..::.:::.:::::..::::. ::.: :.:::::....::. ::
NP_004 ISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI
120 130 140 150 160
>>NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [Homo (191 aa)
initn: 667 init1: 562 opt: 570 Z-score: 502.2 bits: 99.5 E(85289): 3.1e-21
Smith-Waterman score: 570; 54.8% identity (84.7% similar) in 157 aa overlap (1-157:1-154)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
:. ... ......::. . ::.:::::::..::.:::.: .:: .:::::::::
NP_001 MSLALRSELVVDKTKRKK---RRELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRAL
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
::. :: .. :.... :.:.:::..: :: :.:. . :.: .:::::::::::::..::
NP_001 GFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGK
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
::..::.:::.:::::..::::. ::.: :.:::::.
NP_001 ISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEILKNILLLPIWSRCLSLNREFFSE
120 130 140 150 160 170
NP_001 VNQEEFIAIMTGDI
180 190
>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom (149 aa)
initn: 797 init1: 494 opt: 496 Z-score: 441.2 bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
.::::: :..:::.::: :: ::: .::: ..::.:
NP_008 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
10 20 30 40
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .:
NP_008 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
:: .:..: .:::.:::::..::: ::: ::::.:. .::...:
NP_008 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo (149 aa)
initn: 797 init1: 494 opt: 496 Z-score: 441.2 bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
.::::: :..:::.::: :: ::: .::: ..::.:
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
10 20 30 40
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .:
NP_001 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
:: .:..: .:::.:::::..::: ::: ::::.:. .::...:
NP_001 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa (149 aa)
initn: 797 init1: 494 opt: 496 Z-score: 441.2 bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
.::::: :..:::.::: :: ::: .::: ..::.:
NP_005 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
10 20 30 40
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .:
NP_005 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
:: .:..: .:::.:::::..::: ::: ::::.:. .::...:
NP_005 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [ (149 aa)
initn: 797 init1: 494 opt: 496 Z-score: 441.2 bits: 87.9 E(85289): 7.7e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:4-146)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
.::::: :..:::.::: :: ::: .::: ..::.:
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
10 20 30 40
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .:
NP_001 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
:: .:..: .:::.:::::..::: ::: ::::.:. .::...:
NP_001 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c (150 aa)
initn: 797 init1: 494 opt: 496 Z-score: 441.2 bits: 87.9 E(85289): 7.8e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:5-147)
10 20 30 40 50 60
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL
.::::: :..:::.::: :: ::: .::: ..::.:
XP_006 MQADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL
10 20 30 40
70 80 90 100 110 120
pF1KE0 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK
: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:: : .:
XP_006 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
:: .:..: .:::.:::::..::: ::: ::::.:. .::...:
XP_006 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140 150
>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform (197 aa)
initn: 797 init1: 494 opt: 496 Z-score: 439.8 bits: 88.0 E(85289): 9.3e-18
Smith-Waterman score: 496; 52.4% identity (82.5% similar) in 143 aa overlap (24-166:52-194)
10 20 30 40 50
pF1KE0 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKEL
.::::: :..:::.::: :: ::: .:::
NP_001 VVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE0 KVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLF
..::.:: .: . :.. ::.:.: .:.: ..: .:::.:..::.. :..::: .::..:
NP_001 GTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVF
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE0 DDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
: : .: :: .:..: .:::.:::::..::: ::: ::::.:. .::...:
NP_001 DKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
150 160 170 180 190
172 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:03:23 2016 done: Fri Nov 4 01:03:24 2016
Total Scan time: 5.270 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]