FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0141, 224 aa 1>>>pF1KE0141 224 - 224 aa - 224 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5266+/-0.000755; mu= 12.5428+/- 0.045 mean_var=62.3998+/-12.482, 0's: 0 Z-trim(107.7): 13 B-trim: 0 in 0/51 Lambda= 0.162361 statistics sampled from 9728 (9734) to 9728 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.299), width: 16 Scan time: 1.860 The best scores are: opt bits E(32554) CCDS10448.1 FAHD1 gene_id:81889|Hs108|chr16 ( 224) 1510 361.9 1.8e-100 CCDS32367.1 FAHD1 gene_id:81889|Hs108|chr16 ( 248) 1434 344.2 4.5e-95 CCDS45380.1 FAHD1 gene_id:81889|Hs108|chr16 ( 226) 1433 343.9 4.9e-95 CCDS2014.1 FAHD2A gene_id:51011|Hs108|chr2 ( 314) 491 123.3 1.7e-28 CCDS2030.1 FAHD2B gene_id:151313|Hs108|chr2 ( 314) 487 122.4 3.3e-28 >>CCDS10448.1 FAHD1 gene_id:81889|Hs108|chr16 (224 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 1917.2 bits: 361.9 E(32554): 1.8e-100 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII 130 140 150 160 170 180 190 200 210 220 pF1KE0 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY :::::::::::::::::::::::::::::::::::::::::::: CCDS10 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY 190 200 210 220 >>CCDS32367.1 FAHD1 gene_id:81889|Hs108|chr16 (248 aa) initn: 1433 init1: 1433 opt: 1434 Z-score: 1820.3 bits: 344.2 E(32554): 4.5e-95 Smith-Waterman score: 1434; 96.0% identity (98.2% similar) in 223 aa overlap (1-220:1-223) 10 20 30 40 50 60 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII 130 140 150 160 170 180 190 200 210 220 pF1KE0 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGL---VSMTFKVEKPEY :::::::::::::::::::::::::::::::: .... :.: CCDS32 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLRQGLTLSPKLECSSAITAHCSLELPGSS 190 200 210 220 230 240 CCDS32 NPPSASRF >>CCDS45380.1 FAHD1 gene_id:81889|Hs108|chr16 (226 aa) initn: 1433 init1: 1433 opt: 1433 Z-score: 1819.7 bits: 343.9 E(32554): 4.9e-95 Smith-Waterman score: 1433; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII 130 140 150 160 170 180 190 200 210 220 pF1KE0 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY :::::::::::::::::::::::::::::::: CCDS45 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLPKVSSATLPVRLQE 190 200 210 220 >>CCDS2014.1 FAHD2A gene_id:51011|Hs108|chr2 (314 aa) initn: 423 init1: 223 opt: 491 Z-score: 624.9 bits: 123.3 E(32554): 1.7e-28 Smith-Waterman score: 491; 38.0% identity (70.7% similar) in 208 aa overlap (20-219:108-313) 10 20 30 40 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPS .:::: ::.:: .:. : .::..: : . CCDS20 SVARRALAAQLPVLPRSEVTFLAPVTRPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFA 80 90 100 110 120 130 50 60 70 80 90 100 pF1KE0 TAYAPEGSPILMPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQ .. . . ...: .... :.::.::.::. . . . :: .:.:... :..::: : CCDS20 SSIVGPYDEVVLPPQSQEVDWEVELAVVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWQ 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 DECKKKGLPWTLAKSFTASCPVS-AFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFS ...: : :.:.: . ::.. :.: :... :::.::. .::::. : :.:..:.:. CCDS20 --MRRNGKQWLLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFK 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE0 IPYIISYVSKIITLEEGDIILTGTPKGVG-----PV--KENDEIEAGIHGLVSMTFKVEK .:..::...:. ::.:::::: ::: :: :..::.. :. : . :: CCDS20 TEDLIAWVSQFVTFYPGDVILTGTPPGVGVFRKPPVFLKKGDEVQCEIEELGVIINKVV 260 270 280 290 300 310 pF1KE0 PEY >>CCDS2030.1 FAHD2B gene_id:151313|Hs108|chr2 (314 aa) initn: 427 init1: 226 opt: 487 Z-score: 619.8 bits: 122.4 E(32554): 3.3e-28 Smith-Waterman score: 487; 36.8% identity (69.8% similar) in 212 aa overlap (16-219:104-313) 10 20 30 40 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLF : ..:::: ::.:: .:. : .::..: CCDS20 EATLSVARRALAAQLPVLPWSEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIF 80 90 100 110 120 130 50 60 70 80 90 100 pF1KE0 LKPSTAYAPEGSPILMPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTA : ... . . ...: .... :.::.::.::. . . . :: .:.:... :..: CCDS20 SKFASSIVGPYDEVVLPPQSQEVDWEVELAVVIGKKGKHIKATDAMAHVAGFTVAHDVSA 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE0 RDVQDECKKKGLPWTLAKSFTASCPVS-AFVPKEKIPDPHKLKLWLKVNGELRQEGETSS :: ...: : :.:.: . ::.. :.: :... :::.::. .::::. : ..:.. CCDS20 RDWLT--RRNGKQWLLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVNGEVVQSSNTNQ 200 210 220 230 240 250 170 180 190 200 210 pF1KE0 MIFSIPYIISYVSKIITLEEGDIILTGTPKGVG-----PV--KENDEIEAGIHGLVSMTF :.:. .:..::...:. ::.:::::: ::: :: :..::.. :. : . CCDS20 MVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVGVFRKPPVFLKKGDEVQCEIEELGVIIN 260 270 280 290 300 310 220 pF1KE0 KVEKPEY :: CCDS20 KVV 224 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:42:12 2016 done: Fri Nov 4 00:42:13 2016 Total Scan time: 1.860 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]