FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0141, 224 aa 1>>>pF1KE0141 224 - 224 aa - 224 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3347+/-0.000355; mu= 13.9069+/- 0.022 mean_var=64.7121+/-12.974, 0's: 0 Z-trim(114.2): 11 B-trim: 0 in 0/51 Lambda= 0.159434 statistics sampled from 23842 (23847) to 23842 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.28), width: 16 Scan time: 5.500 The best scores are: opt bits E(85289) NP_112485 (OMIM: 616320) acylpyruvase FAHD1, mitoc ( 224) 1510 355.8 3.4e-98 NP_001018114 (OMIM: 616320) acylpyruvase FAHD1, mi ( 248) 1434 338.3 6.8e-93 NP_001135870 (OMIM: 616320) acylpyruvase FAHD1, mi ( 226) 1433 338.1 7.4e-93 >>NP_112485 (OMIM: 616320) acylpyruvase FAHD1, mitochond (224 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 1883.8 bits: 355.8 E(85289): 3.4e-98 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII 130 140 150 160 170 180 190 200 210 220 pF1KE0 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY :::::::::::::::::::::::::::::::::::::::::::: NP_112 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY 190 200 210 220 >>NP_001018114 (OMIM: 616320) acylpyruvase FAHD1, mitoch (248 aa) initn: 1433 init1: 1433 opt: 1434 Z-score: 1788.7 bits: 338.3 E(85289): 6.8e-93 Smith-Waterman score: 1434; 96.0% identity (98.2% similar) in 223 aa overlap (1-220:1-223) 10 20 30 40 50 60 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII 130 140 150 160 170 180 190 200 210 220 pF1KE0 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGL---VSMTFKVEKPEY :::::::::::::::::::::::::::::::: .... :.: NP_001 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLRQGLTLSPKLECSSAITAHCSLELPGSS 190 200 210 220 230 240 NP_001 NPPSASRF >>NP_001135870 (OMIM: 616320) acylpyruvase FAHD1, mitoch (226 aa) initn: 1433 init1: 1433 opt: 1433 Z-score: 1788.1 bits: 338.1 E(85289): 7.4e-93 Smith-Waterman score: 1433; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KE0 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII 130 140 150 160 170 180 190 200 210 220 pF1KE0 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY :::::::::::::::::::::::::::::::: NP_001 TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLPKVSSATLPVRLQE 190 200 210 220 224 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:42:13 2016 done: Fri Nov 4 00:42:14 2016 Total Scan time: 5.500 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]