FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0144, 167 aa 1>>>pF1KE0144 167 - 167 aa - 167 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5814+/-0.000306; mu= 16.1798+/- 0.019 mean_var=58.5130+/-11.646, 0's: 0 Z-trim(116.2): 18 B-trim: 0 in 0/55 Lambda= 0.167667 statistics sampled from 27222 (27239) to 27222 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.319), width: 16 Scan time: 5.660 The best scores are: opt bits E(85289) NP_998760 (OMIM: 255125,611911) iron-sulfur cluste ( 167) 1059 263.8 9.1e-71 NP_001306971 (OMIM: 255125,611911) iron-sulfur clu ( 154) 887 222.2 2.8e-58 NP_001288069 (OMIM: 255125,611911) iron-sulfur clu ( 154) 887 222.2 2.8e-58 NP_001288070 (OMIM: 255125,611911) iron-sulfur clu ( 156) 887 222.2 2.9e-58 NP_055116 (OMIM: 255125,611911) iron-sulfur cluste ( 142) 840 210.8 7.1e-55 XP_011536403 (OMIM: 255125,611911) PREDICTED: iron ( 128) 715 180.5 8.3e-46 XP_011536402 (OMIM: 255125,611911) PREDICTED: iron ( 129) 668 169.2 2.2e-42 >>NP_998760 (OMIM: 255125,611911) iron-sulfur cluster as (167 aa) initn: 1059 init1: 1059 opt: 1059 Z-score: 1391.5 bits: 263.8 E(85289): 9.1e-71 Smith-Waterman score: 1059; 98.8% identity (99.4% similar) in 167 aa overlap (1-167:1-167) 10 20 30 40 50 60 pF1KE0 MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG :::::: ::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_998 MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 70 80 90 100 110 120 130 140 150 160 pF1KE0 KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK ::::::::::::::::::::::::::::::::::::::::::::::: NP_998 KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK 130 140 150 160 >>NP_001306971 (OMIM: 255125,611911) iron-sulfur cluster (154 aa) initn: 887 init1: 887 opt: 887 Z-score: 1167.2 bits: 222.2 E(85289): 2.8e-58 Smith-Waterman score: 887; 98.6% identity (99.3% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KE0 MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG :::::: ::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 70 80 90 100 110 120 130 140 150 160 pF1KE0 KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK ::::::::::::::::::: NP_001 KNTDIAKELCLPPVKLHCSKSVLFPAEEKTQLSP 130 140 150 >>NP_001288069 (OMIM: 255125,611911) iron-sulfur cluster (154 aa) initn: 887 init1: 887 opt: 887 Z-score: 1167.2 bits: 222.2 E(85289): 2.8e-58 Smith-Waterman score: 887; 98.6% identity (99.3% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KE0 MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG :::::: ::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 70 80 90 100 110 120 130 140 150 160 pF1KE0 KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK ::::::::::::::::::: NP_001 KNTDIAKELCLPPVKLHCSKSVLFPAEEKTQLSP 130 140 150 >>NP_001288070 (OMIM: 255125,611911) iron-sulfur cluster (156 aa) initn: 887 init1: 887 opt: 887 Z-score: 1167.1 bits: 222.2 E(85289): 2.9e-58 Smith-Waterman score: 887; 98.6% identity (99.3% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KE0 MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG :::::: ::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI 70 80 90 100 110 120 130 140 150 160 pF1KE0 KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK ::::::::::::::::::: NP_001 KNTDIAKELCLPPVKLHCSRKEGMRNISLNASMEVY 130 140 150 >>NP_055116 (OMIM: 255125,611911) iron-sulfur cluster as (142 aa) initn: 840 init1: 840 opt: 840 Z-score: 1106.2 bits: 210.8 E(85289): 7.1e-55 Smith-Waterman score: 840; 99.2% identity (100.0% similar) in 130 aa overlap (38-167:13-142) 10 20 30 40 50 60 pF1KE0 RLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAP .::::::::::::::::::::::::::::: NP_055 MVLIDMSVDLSTQVVDHYENPRNVGSLDKTSKNVGTGLVGAP 10 20 30 40 70 80 90 100 110 120 pF1KE0 ACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK 50 60 70 80 90 100 130 140 150 160 pF1KE0 ELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK :::::::::::::::::::::::::::::::::::::::: NP_055 ELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK 110 120 130 140 >>XP_011536403 (OMIM: 255125,611911) PREDICTED: iron-sul (128 aa) initn: 715 init1: 715 opt: 715 Z-score: 943.4 bits: 180.5 E(85289): 8.3e-46 Smith-Waterman score: 715; 98.2% identity (99.1% similar) in 113 aa overlap (1-113:1-113) 10 20 30 40 50 60 pF1KE0 MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG :::::: ::::.:::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTCWLKMQS 70 80 90 100 110 120 130 140 150 160 pF1KE0 KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK XP_011 RPPWLITN >>XP_011536402 (OMIM: 255125,611911) PREDICTED: iron-sul (129 aa) initn: 668 init1: 668 opt: 668 Z-score: 881.9 bits: 169.2 E(85289): 2.2e-42 Smith-Waterman score: 668; 99.0% identity (100.0% similar) in 102 aa overlap (38-139:13-114) 10 20 30 40 50 60 pF1KE0 RLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAP .::::::::::::::::::::::::::::: XP_011 MVLIDMSVDLSTQVVDHYENPRNVGSLDKTSKNVGTGLVGAP 10 20 30 40 70 80 90 100 110 120 pF1KE0 ACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAK 50 60 70 80 90 100 130 140 150 160 pF1KE0 ELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK :::::::::::: XP_011 ELCLPPVKLHCSKSVLFPAEEKTQLSP 110 120 167 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:28:20 2016 done: Fri Nov 4 00:28:21 2016 Total Scan time: 5.660 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]