FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0147, 204 aa 1>>>pF1KE0147 204 - 204 aa - 204 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8381+/-0.000252; mu= 17.2314+/- 0.016 mean_var=71.7320+/-14.052, 0's: 0 Z-trim(121.4): 17 B-trim: 0 in 0/57 Lambda= 0.151432 statistics sampled from 37888 (37905) to 37888 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.444), width: 16 Scan time: 6.490 The best scores are: opt bits E(85289) XP_016883562 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 XP_006723693 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 XP_016883563 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 XP_016883564 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 NP_001310611 (OMIM: 610666) neurensin-2 isoform 1 ( 204) 1434 321.2 7e-88 XP_011527664 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 XP_011527665 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 NP_001310612 (OMIM: 610666) neurensin-2 isoform 1 ( 204) 1434 321.2 7e-88 NP_079234 (OMIM: 610666) neurensin-2 isoform 1 [Ho ( 204) 1434 321.2 7e-88 NP_001310610 (OMIM: 610666) neurensin-2 isoform 1 ( 204) 1434 321.2 7e-88 NP_001310609 (OMIM: 610666) neurensin-2 isoform 1 ( 204) 1434 321.2 7e-88 NP_001310614 (OMIM: 610666) neurensin-2 isoform 1 ( 204) 1434 321.2 7e-88 NP_001310613 (OMIM: 610666) neurensin-2 isoform 1 ( 204) 1434 321.2 7e-88 XP_011527662 (OMIM: 610666) PREDICTED: neurensin-2 ( 204) 1434 321.2 7e-88 NP_001310608 (OMIM: 610666) neurensin-2 isoform 2 ( 160) 697 160.1 1.7e-39 XP_016883565 (OMIM: 610666) PREDICTED: neurensin-2 ( 157) 500 117.1 1.5e-26 NP_542454 (OMIM: 616630) neurensin-1 [Homo sapiens ( 195) 354 85.3 7.2e-17 >>XP_016883562 (OMIM: 610666) PREDICTED: neurensin-2 iso (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: XP_016 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>XP_006723693 (OMIM: 610666) PREDICTED: neurensin-2 iso (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_006 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: XP_006 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>XP_016883563 (OMIM: 610666) PREDICTED: neurensin-2 iso (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: XP_016 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>XP_016883564 (OMIM: 610666) PREDICTED: neurensin-2 iso (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: XP_016 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>NP_001310611 (OMIM: 610666) neurensin-2 isoform 1 [Hom (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: NP_001 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: NP_001 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>XP_011527664 (OMIM: 610666) PREDICTED: neurensin-2 iso (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_011 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: XP_011 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>XP_011527665 (OMIM: 610666) PREDICTED: neurensin-2 iso (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_011 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: XP_011 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>NP_001310612 (OMIM: 610666) neurensin-2 isoform 1 [Hom (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: NP_001 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: NP_001 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>NP_079234 (OMIM: 610666) neurensin-2 isoform 1 [Homo s (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: NP_079 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: NP_079 SWFSPPASPFGQSSVQTIQPKRDS 190 200 >>NP_001310610 (OMIM: 610666) neurensin-2 isoform 1 [Hom (204 aa) initn: 1434 init1: 1434 opt: 1434 Z-score: 1698.7 bits: 321.2 E(85289): 7e-88 Smith-Waterman score: 1434; 99.5% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KE0 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMPSCNRSCSCSRGPSVEDGKWYGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRTADYNQALGTCRLAGT ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: NP_001 CWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCVAAGVLLAICLFWAMIGWLSQDTKAEPLDPEADSHVEVFGDEPEQQLSPIFRNASGQ 130 140 150 160 170 180 190 200 pF1KE0 SWFSPPASPFGQSSVQTIQPKRDS :::::::::::::::::::::::: NP_001 SWFSPPASPFGQSSVQTIQPKRDS 190 200 204 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:23:32 2016 done: Fri Nov 4 00:23:33 2016 Total Scan time: 6.490 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]