FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0148, 226 aa 1>>>pF1KE0148 226 - 226 aa - 226 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1566+/-0.00034; mu= 14.7239+/- 0.021 mean_var=65.1176+/-13.307, 0's: 0 Z-trim(115.1): 32 B-trim: 278 in 1/53 Lambda= 0.158937 statistics sampled from 25371 (25399) to 25371 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.298), width: 16 Scan time: 6.600 The best scores are: opt bits E(85289) NP_057001 (OMIM: 602321) glutathione S-transferase ( 226) 1517 356.3 2.4e-98 NP_001137152 (OMIM: 602321) glutathione S-transfer ( 214) 882 210.7 1.6e-54 NP_001137151 (OMIM: 602321) glutathione S-transfer ( 282) 882 210.7 2e-54 NP_001137153 (OMIM: 602321) glutathione S-transfer ( 183) 877 209.5 3.1e-54 >>NP_057001 (OMIM: 602321) glutathione S-transferase kap (226 aa) initn: 1517 init1: 1517 opt: 1517 Z-score: 1886.5 bits: 356.3 E(85289): 2.4e-98 Smith-Waterman score: 1517; 99.6% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIAAPKVKNQLKETTEAACRYGA ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_057 LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 130 140 150 160 170 180 190 200 210 220 pF1KE0 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL :::::::::::::::::::::::::::::::::::::::::::::: NP_057 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 190 200 210 220 >>NP_001137152 (OMIM: 602321) glutathione S-transferase (214 aa) initn: 1429 init1: 882 opt: 882 Z-score: 1099.9 bits: 210.7 E(85289): 1.6e-54 Smith-Waterman score: 1409; 94.2% identity (94.7% similar) in 226 aa overlap (1-226:1-214) 10 20 30 40 50 60 pF1KE0 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIAAPKVKNQLKETTEAACRYGA :::::::: ::::::::::::::::::::.::::::::::::::::::: NP_001 LWMRVWSR------------AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 130 140 150 160 190 200 210 220 pF1KE0 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL :::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 170 180 190 200 210 >>NP_001137151 (OMIM: 602321) glutathione S-transferase (282 aa) initn: 882 init1: 882 opt: 882 Z-score: 1098.1 bits: 210.7 E(85289): 2e-54 Smith-Waterman score: 1228; 77.9% identity (78.3% similar) in 258 aa overlap (1-202:1-258) 10 20 30 40 50 60 pF1KE0 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 70 80 90 100 110 120 pF1KE0 LWMRVWSR---------------------------------------------------- :::::::: NP_001 LWMRVWSRVSVGLWESSGRTLDDFLTFPRHVFRVMILPPPGGSTVLPVTPLSPHRLPAVF 130 140 150 160 170 180 130 140 150 160 170 180 pF1KE0 ----NEDITEPQSILAAAEKAGMSAEQAQGLLEKIAAPKVKNQLKETTEAACRYGAFGLP ::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 SSSQNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLP 190 200 210 220 230 240 190 200 210 220 pF1KE0 ITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL :::::::::::::::::: NP_001 ITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 250 260 270 280 >>NP_001137153 (OMIM: 602321) glutathione S-transferase (183 aa) initn: 872 init1: 872 opt: 877 Z-score: 1094.7 bits: 209.5 E(85289): 3.1e-54 Smith-Waterman score: 1122; 80.5% identity (81.0% similar) in 226 aa overlap (1-226:1-183) 10 20 30 40 50 60 pF1KE0 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSG-------- 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE ::::::::::::::::::::::::: NP_001 -----------------------------------SLSAMRFLTAVNLEHPEMLEKASRE 60 70 130 140 150 160 170 180 pF1KE0 LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIAAPKVKNQLKETTEAACRYGA ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_001 LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 80 90 100 110 120 130 190 200 210 220 pF1KE0 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL :::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 140 150 160 170 180 226 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:19:48 2016 done: Fri Nov 4 00:19:49 2016 Total Scan time: 6.600 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]