FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0149, 156 aa 1>>>pF1KE0149 156 - 156 aa - 156 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0365+/-0.00029; mu= -6.8819+/- 0.018 mean_var=255.4200+/-51.130, 0's: 0 Z-trim(126.1): 7 B-trim: 0 in 0/62 Lambda= 0.080250 statistics sampled from 51342 (51349) to 51342 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.855), E-opt: 0.2 (0.602), width: 16 Scan time: 6.520 The best scores are: opt bits E(85289) XP_006724557 (OMIM: 300533) PREDICTED: variable ch ( 166) 982 124.8 6.1e-29 NP_057463 (OMIM: 300533) variable charge X-linked ( 186) 982 124.8 6.7e-29 NP_001001888 (OMIM: 300981) variable charge X-link ( 246) 976 124.2 1.3e-28 XP_011543792 (OMIM: 300229) PREDICTED: variable ch ( 186) 970 123.4 1.7e-28 NP_038480 (OMIM: 300229) variable charge X-linked ( 206) 970 123.4 1.9e-28 NP_057462 (OMIM: 300532) variable charge X-linked ( 139) 817 105.6 3e-23 NP_004670 (OMIM: 400012,415000) testis-specific ba ( 125) 730 95.5 2.9e-20 >>XP_006724557 (OMIM: 300533) PREDICTED: variable charge (166 aa) initn: 982 init1: 982 opt: 982 Z-score: 640.6 bits: 124.8 E(85289): 6.1e-29 Smith-Waterman score: 987; 94.0% identity (94.0% similar) in 166 aa overlap (1-156:1-166) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV 70 80 90 100 110 120 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQES----------EMEELPSV :::::::::::::::::::::::::::: :::::::: XP_006 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEELPSV 130 140 150 160 >>NP_057463 (OMIM: 300533) variable charge X-linked prot (186 aa) initn: 982 init1: 982 opt: 982 Z-score: 639.9 bits: 124.8 E(85289): 6.7e-29 Smith-Waterman score: 982; 98.7% identity (100.0% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV 70 80 90 100 110 120 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::::::::::::::::::::::::::::..:: NP_057 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 130 140 150 160 170 180 NP_057 EELPSV >>NP_001001888 (OMIM: 300981) variable charge X-linked p (246 aa) initn: 976 init1: 976 opt: 976 Z-score: 634.4 bits: 124.2 E(85289): 1.3e-28 Smith-Waterman score: 976; 98.0% identity (99.3% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSPKPRASGPPAKAKEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV 70 80 90 100 110 120 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::::::::::::::::::::::::::::..:: NP_001 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESEVEEPLSQESQV 130 140 150 160 170 180 NP_001 EEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPLSQESEMEEPLSQESEM 190 200 210 220 230 240 >-- initn: 321 init1: 321 opt: 347 Z-score: 240.8 bits: 51.4 E(85289): 1.1e-06 Smith-Waterman score: 347; 71.4% identity (88.1% similar) in 84 aa overlap (76-156:163-246) 50 60 70 80 90 100 pF1KE0 RRGRRGKKGAATKMAAVTAPEAESGPAAPGPSDQPSQ-ELP-QHELPPEEPVSEGTQ-HD : .: :. : : ..: :::.:. .. .. NP_001 PLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESEVEEPLSQESQVEEPLSQESEVEE 140 150 160 170 180 190 110 120 130 140 150 pF1KE0 PLSQESELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::::::..:::::::::.:::::::::::::::::::.:::::::::::::::: NP_001 PLSQESQVEEPLSQESEMEEPLSQESQVEEPLSQESEMEEPLSQESEMEELPSV 200 210 220 230 240 >>XP_011543792 (OMIM: 300229) PREDICTED: variable charge (186 aa) initn: 970 init1: 970 opt: 970 Z-score: 632.4 bits: 123.4 E(85289): 1.7e-28 Smith-Waterman score: 970; 97.4% identity (100.0% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::: XP_011 AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 70 80 90 100 110 120 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::::::::::::::::::::::::::::..:: XP_011 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 130 140 150 160 170 180 XP_011 EELPSV >>NP_038480 (OMIM: 300229) variable charge X-linked prot (206 aa) initn: 970 init1: 970 opt: 970 Z-score: 631.7 bits: 123.4 E(85289): 1.9e-28 Smith-Waterman score: 970; 97.4% identity (100.0% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_038 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::: NP_038 AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 70 80 90 100 110 120 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::::::::::::::::::::::::::::..:: NP_038 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 130 140 150 160 170 180 NP_038 EEPLSQESQVEEPPSQESEMEELPSV 190 200 >-- initn: 303 init1: 303 opt: 303 Z-score: 214.4 bits: 46.2 E(85289): 3.3e-05 Smith-Waterman score: 303; 88.9% identity (98.1% similar) in 54 aa overlap (103-156:153-206) 80 90 100 110 120 130 pF1KE0 APGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEVEEPLSQESQVEE :::::::.::::::::.:::::::::..:: NP_038 PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEE 130 140 150 160 170 180 140 150 pF1KE0 PLSQESEVEEPLSQESEMEELPSV ::::::.:::: :::::::::::: NP_038 PLSQESQVEEPPSQESEMEELPSV 190 200 >>NP_057462 (OMIM: 300532) variable charge X-linked prot (139 aa) initn: 949 init1: 811 opt: 817 Z-score: 538.5 bits: 105.6 E(85289): 3e-23 Smith-Waterman score: 817; 89.2% identity (94.2% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::.:::::::::::::::::::::::::::::::::::::::.:::::::::: NP_057 AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESEVEEPLSQESEV 70 80 90 100 110 120 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::::. :.:. .. NP_057 EEPLTVWMASFSPVSESTD 130 >>NP_004670 (OMIM: 400012,415000) testis-specific basic (125 aa) initn: 846 init1: 727 opt: 730 Z-score: 484.7 bits: 95.5 E(85289): 2.9e-20 Smith-Waterman score: 730; 89.6% identity (94.4% similar) in 125 aa overlap (1-125:1-124) 10 20 30 40 50 60 pF1KE0 MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA :::::::::::::: :.:::::::::::: :::::::::.::.::: ::::::::::::: NP_004 MSPKPRASGPPAKAKETGKRKSSSQPSPSGPKKKTTKVAEKGEAVRGGRRGKKGAATKMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::. .. NP_004 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSK-GRP 70 80 90 100 110 130 140 150 pF1KE0 EEPLSQESQVEEPLSQESEVEEPLSQESEMEELPSV ::: NP_004 STPLSP 120 156 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:14:14 2016 done: Fri Nov 4 00:14:15 2016 Total Scan time: 6.520 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]