FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0152, 131 aa 1>>>pF1KE0152 131 - 131 aa - 131 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8172+/-0.000354; mu= -3.3670+/- 0.022 mean_var=220.8679+/-44.408, 0's: 0 Z-trim(122.0): 6 B-trim: 0 in 0/55 Lambda= 0.086299 statistics sampled from 39445 (39454) to 39445 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.463), width: 16 Scan time: 5.390 The best scores are: opt bits E(85289) NP_001070246 (OMIM: 608295) protein FAM107A isofor ( 144) 457 68.0 5.4e-12 NP_009108 (OMIM: 608295) protein FAM107A isoform a ( 144) 457 68.0 5.4e-12 NP_001269642 (OMIM: 608295) protein FAM107A isofor ( 172) 457 68.1 6.2e-12 NP_001269643 (OMIM: 608295) protein FAM107A isofor ( 175) 457 68.1 6.3e-12 >>NP_001070246 (OMIM: 608295) protein FAM107A isoform a (144 aa) initn: 326 init1: 326 opt: 457 Z-score: 336.3 bits: 68.0 E(85289): 5.4e-12 Smith-Waterman score: 457; 54.5% identity (84.1% similar) in 132 aa overlap (1-130:16-143) 10 20 30 40 pF1KE0 MAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGL ::.:.: : :::::.:.::.::::.::.::.::::::::..::: NP_001 MYSEIQRERADIGGLMARPEYREW-NPELIKPKKLLNPVKASRSHQELHRELLMNHRRGL 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 APQNKPELQKVMEKRKRDQVIKQKEEE--AQKKKSDLEIELLKRQQKLEQLELEKQKLQE . ..:::::.:.:.:.:.:.::.:.:: :.. . .: :::.:::.:.::: .: NP_001 GVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEK--- 60 70 80 90 100 110 110 120 130 pF1KE0 EQENAPEFVKVKGNLRRTGQEVAQAQES :...::::.::. :::: . ... .: NP_001 EEDHAPEFIKVRENLRRIATLTSEEREL 120 130 140 >>NP_009108 (OMIM: 608295) protein FAM107A isoform a [Ho (144 aa) initn: 326 init1: 326 opt: 457 Z-score: 336.3 bits: 68.0 E(85289): 5.4e-12 Smith-Waterman score: 457; 54.5% identity (84.1% similar) in 132 aa overlap (1-130:16-143) 10 20 30 40 pF1KE0 MAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGL ::.:.: : :::::.:.::.::::.::.::.::::::::..::: NP_009 MYSEIQRERADIGGLMARPEYREW-NPELIKPKKLLNPVKASRSHQELHRELLMNHRRGL 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 APQNKPELQKVMEKRKRDQVIKQKEEE--AQKKKSDLEIELLKRQQKLEQLELEKQKLQE . ..:::::.:.:.:.:.:.::.:.:: :.. . .: :::.:::.:.::: .: NP_009 GVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEK--- 60 70 80 90 100 110 110 120 130 pF1KE0 EQENAPEFVKVKGNLRRTGQEVAQAQES :...::::.::. :::: . ... .: NP_009 EEDHAPEFIKVRENLRRIATLTSEEREL 120 130 140 >>NP_001269642 (OMIM: 608295) protein FAM107A isoform b (172 aa) initn: 326 init1: 326 opt: 457 Z-score: 335.2 bits: 68.1 E(85289): 6.2e-12 Smith-Waterman score: 457; 54.5% identity (84.1% similar) in 132 aa overlap (1-130:44-171) 10 20 30 pF1KE0 MAEPDYIEDDNPELIRPQKLINPVKTSRNH ::.:.: : :::::.:.::.::::.::.: NP_001 DATGLYRAVLLRSAAMYSEIQRERADIGGLMARPEYREW-NPELIKPKKLLNPVKASRSH 20 30 40 50 60 70 40 50 60 70 80 pF1KE0 QDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE--AQKKKSDLEIELLKRQ :.::::::::..:::. ..:::::.:.:.:.:.:.::.:.:: :.. . .: :::.:: NP_001 QELHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQ 80 90 100 110 120 130 90 100 110 120 130 pF1KE0 QKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQES :.:.::: .: :...::::.::. :::: . ... .: NP_001 QRLNQLEKPPEK---EEDHAPEFIKVRENLRRIATLTSEEREL 140 150 160 170 >>NP_001269643 (OMIM: 608295) protein FAM107A isoform c (175 aa) initn: 326 init1: 326 opt: 457 Z-score: 335.1 bits: 68.1 E(85289): 6.3e-12 Smith-Waterman score: 457; 54.5% identity (84.1% similar) in 132 aa overlap (1-130:47-174) 10 20 30 pF1KE0 MAEPDYIEDDNPELIRPQKLINPVKTSRNH ::.:.: : :::::.:.::.::::.::.: NP_001 FHSENEKQRRNGSAAMYSEIQRERADIGGLMARPEYREW-NPELIKPKKLLNPVKASRSH 20 30 40 50 60 70 40 50 60 70 80 pF1KE0 QDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE--AQKKKSDLEIELLKRQ :.::::::::..:::. ..:::::.:.:.:.:.:.::.:.:: :.. . .: :::.:: NP_001 QELHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQ 80 90 100 110 120 130 90 100 110 120 130 pF1KE0 QKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQES :.:.::: .: :...::::.::. :::: . ... .: NP_001 QRLNQLEKPPEK---EEDHAPEFIKVRENLRRIATLTSEEREL 140 150 160 170 131 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:57:07 2016 done: Thu Nov 3 23:57:08 2016 Total Scan time: 5.390 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]