FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0153, 346 aa 1>>>pF1KE0153 346 - 346 aa - 346 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0695+/-0.000345; mu= 18.1672+/- 0.022 mean_var=72.3155+/-14.823, 0's: 0 Z-trim(114.1): 9 B-trim: 1262 in 1/51 Lambda= 0.150820 statistics sampled from 23716 (23718) to 23716 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.278), width: 16 Scan time: 8.050 The best scores are: opt bits E(85289) NP_060337 (OMIM: 616614) histone PARylation factor ( 346) 2323 514.6 1.3e-145 XP_016863821 (OMIM: 616614) PREDICTED: UPF0609 pro ( 367) 2064 458.3 1.2e-128 >>NP_060337 (OMIM: 616614) histone PARylation factor 1 [ (346 aa) initn: 2323 init1: 2323 opt: 2323 Z-score: 2735.5 bits: 514.6 E(85289): 1.3e-145 Smith-Waterman score: 2323; 99.7% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KE0 MVGGGGKRRPGGEGPQCEKTTDVKKSKFCEADVSSDLRKEVENHYKLSLPEDFYHFWKFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MVGGGGKRRPGGEGPQCEKTTDVKKSKFCEADVSSDLRKEVENHYKLSLPEDFYHFWKFC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EELDPEKPSDSLSASLGLQLVGPYDILAGKHKTKKKSTGLNFNLHWRFYYDPPEFQTIII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EELDPEKPSDSLSASLGLQLVGPYDILAGKHKTKKKSTGLNFNLHWRFYYDPPEFQTIII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GDNKTQYHMGYFRDSPDEFPVYVGINEAKKNCIIVPNGDNVFAAVKLFLTKKLKEITDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: NP_060 GDNKTQYHMGYFRDSPDEFPVYVGINEAKKNCIIVPNGDNVFAAVKLFLTKKLREITDKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KINLLKNIDEKLTEAARELGYSLEQRTVKMKQRDKKVVTKTFHGAGLVVPVDKNDVGYRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KINLLKNIDEKLTEAARELGYSLEQRTVKMKQRDKKVVTKTFHGAGLVVPVDKNDVGYRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LPETDADLKRICKTIVEAASDEERLKAFAPIQEMMTFVQFANDECDYGMGLELGMDLFCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LPETDADLKRICKTIVEAASDEERLKAFAPIQEMMTFVQFANDECDYGMGLELGMDLFCY 250 260 270 280 290 300 310 320 330 340 pF1KE0 GSHYFHKVAGQLLPLAYNLLKRNLFAEIIEEHLANRSQENIDQLAA :::::::::::::::::::::::::::::::::::::::::::::: NP_060 GSHYFHKVAGQLLPLAYNLLKRNLFAEIIEEHLANRSQENIDQLAA 310 320 330 340 >>XP_016863821 (OMIM: 616614) PREDICTED: UPF0609 protein (367 aa) initn: 2053 init1: 2053 opt: 2064 Z-score: 2430.5 bits: 458.3 E(85289): 1.2e-128 Smith-Waterman score: 2064; 97.2% identity (98.4% similar) in 316 aa overlap (1-316:1-315) 10 20 30 40 50 60 pF1KE0 MVGGGGKRRPGGEGPQCEKTTDVKKSKFCEADVSSDLRKEVENHYKLSLPEDFYHFWKFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVGGGGKRRPGGEGPQCEKTTDVKKSKFCEADVSSDLRKEVENHYKLSLPEDFYHFWKFC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EELDPEKPSDSLSASLGLQLVGPYDILAGKHKTKKKSTGLNFNLHWRFYYDPPEFQTIII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELDPEKPSDSLSASLGLQLVGPYDILAGKHKTKKKSTGLNFNLHWRFYYDPPEFQTIII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 GDNKTQYHMGYFRDSPDEFPVYVGINEAKKNCIIVPNGDNVFAAVKLFLTKKLKEITDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: XP_016 GDNKTQYHMGYFRDSPDEFPVYVGINEAKKNCIIVPNGDNVFAAVKLFLTKKLREITDKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KINLLKNIDEKLTEAARELGYSLEQRTVKMKQRDKKVVTKTFHGAGLVVPVDKNDVGYRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINLLKNIDEKLTEAARELGYSLEQRTVKMKQRDKKVVTKTFHGAGLVVPVDKNDVGYRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LPETDADLKRICKTIVEAASDEERLKAFAPIQEMMTFVQFANDECDYGMGLELGMDLFCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETDADLKRICKTIVEAASDEERLKAFAPIQEMMTFVQFANDECDYGMGLELGMDLFCY 250 260 270 280 290 300 310 320 330 340 pF1KE0 GSHYFHKVAGQLLPLAYNLLKRNLFAEIIEEHLANRSQENIDQLAA ::: .:. .::: : XP_016 GSHVSKKTL-HLLPTATPPSSPRDIHPHMNTCTFIPPNSSRGKTGIQLVFQNEVFEVIFF 310 320 330 340 350 346 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:49:31 2016 done: Thu Nov 3 23:49:32 2016 Total Scan time: 8.050 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]