FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0155, 243 aa 1>>>pF1KE0155 243 - 243 aa - 243 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8738+/-0.000757; mu= 16.7988+/- 0.046 mean_var=63.2589+/-12.940, 0's: 0 Z-trim(108.2): 15 B-trim: 0 in 0/47 Lambda= 0.161255 statistics sampled from 10052 (10060) to 10052 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.309), width: 16 Scan time: 2.150 The best scores are: opt bits E(32554) CCDS45306.1 SCAMP5 gene_id:192683|Hs108|chr15 ( 235) 1600 380.5 5.5e-106 CCDS45903.1 SCAMP4 gene_id:113178|Hs108|chr19 ( 229) 976 235.3 2.7e-62 CCDS78025.1 SCAMP1 gene_id:9522|Hs108|chr5 ( 312) 754 183.7 1.2e-46 CCDS75264.1 SCAMP1 gene_id:9522|Hs108|chr5 ( 338) 754 183.8 1.3e-46 CCDS1106.1 SCAMP3 gene_id:10067|Hs108|chr1 ( 321) 751 183.0 2e-46 CCDS1105.1 SCAMP3 gene_id:10067|Hs108|chr1 ( 347) 751 183.1 2.1e-46 CCDS10271.1 SCAMP2 gene_id:10066|Hs108|chr15 ( 329) 747 182.1 3.9e-46 >>CCDS45306.1 SCAMP5 gene_id:192683|Hs108|chr15 (235 aa) initn: 989 init1: 945 opt: 1600 Z-score: 2016.3 bits: 380.5 E(32554): 5.5e-106 Smith-Waterman score: 1600; 96.7% identity (96.7% similar) in 243 aa overlap (1-243:1-235) 10 20 30 40 50 60 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV :::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS45 IQAVGIPGWGVC--------GWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS 180 190 200 210 220 230 pF1KE0 NEM ::: CCDS45 NEM >>CCDS45903.1 SCAMP4 gene_id:113178|Hs108|chr19 (229 aa) initn: 978 init1: 705 opt: 976 Z-score: 1231.9 bits: 235.3 E(32554): 2.7e-62 Smith-Waterman score: 981; 55.8% identity (79.8% similar) in 242 aa overlap (1-242:1-227) 10 20 30 40 50 60 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLA :.:: :::::::::::.::::::.: .:: .: ..::.: :::. .::.:::..::: CCDS45 MSEKENNFPPLPKFIPVKPCFYQNFSDEIPVEHQVLVKRIYRLWMFYCATLGVNLIACLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI : ::::..:::::::.::.:::::.:::::::.::::..::::.:::::: : ::.:... CCDS45 WWIGGGSGTNFGLAFVWLLLFTPCGYVCWFRPVYKAFRADSSFNFMAFFFIFGAQFVLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IQAVGIPGWGVCPTLASSCSGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMV :::.:. :::.: ::...:.:: . :.:::::.:..::.: :.. ::. : CCDS45 IQAIGFSGWGAC--------GWLSAIGFFQYSPGAAVVMLLPAIMFSVSAAMMAIAIMKV 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 HKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYS :..:::.::::.::: ::.::.:.:: ..: : : . :. : ..:.: : CCDS45 HRIYRGAGGSFQKAQTEWNTGTWRNPPSREAQYNNFSGNSL-----PE--YPTVPSYPGS 180 190 200 210 220 pF1KE0 NEM .. CCDS45 GQWP >>CCDS78025.1 SCAMP1 gene_id:9522|Hs108|chr5 (312 aa) initn: 796 init1: 315 opt: 754 Z-score: 950.8 bits: 183.7 E(32554): 1.2e-46 Smith-Waterman score: 754; 47.0% identity (79.5% similar) in 219 aa overlap (6-223:92-302) 10 20 30 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVS ::.::::. .:. ::::::: .::: . . CCDS78 LKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQK 70 80 90 100 110 120 40 50 60 70 80 90 pF1KE0 MTKRLYYLWMLNSVTLAVNLVGCLAWL-IGGGGATNFGLAFLWLILFTPCSYVCWFRPIY .: .:::::...::: .:. :::::. . .. :..:::..::..::::::.:::.::.: CCDS78 TVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLY 130 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 KAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFGTNIG ::..:::: :..:::... :... ..::.:. .:: : :::.... .. :: CCDS78 GAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNC--------GWISSLTGLNQNIP 190 200 210 220 230 160 170 180 190 200 210 pF1KE0 SAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQN ...:.: ...::. ::.:.. .. :: .:: .:.:: :::.:..::. .: :: :: : CCDS78 VGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAAN 240 250 260 270 280 290 220 230 240 pF1KE0 AAMGAAQGAMNQPQTQYSATPNYTYSNEM :: ::..: CCDS78 AASTAASSAAQNAFKGNQI 300 310 >>CCDS75264.1 SCAMP1 gene_id:9522|Hs108|chr5 (338 aa) initn: 796 init1: 315 opt: 754 Z-score: 950.4 bits: 183.8 E(32554): 1.3e-46 Smith-Waterman score: 754; 47.0% identity (79.5% similar) in 219 aa overlap (6-223:118-328) 10 20 30 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVS ::.::::. .:. ::::::: .::: . . CCDS75 LKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQK 90 100 110 120 130 140 40 50 60 70 80 90 pF1KE0 MTKRLYYLWMLNSVTLAVNLVGCLAWL-IGGGGATNFGLAFLWLILFTPCSYVCWFRPIY .: .:::::...::: .:. :::::. . .. :..:::..::..::::::.:::.::.: CCDS75 TVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLY 150 160 170 180 190 200 100 110 120 130 140 150 pF1KE0 KAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFGTNIG ::..:::: :..:::... :... ..::.:. .:: : :::.... .. :: CCDS75 GAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNC--------GWISSLTGLNQNIP 210 220 230 240 250 160 170 180 190 200 210 pF1KE0 SAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQN ...:.: ...::. ::.:.. .. :: .:: .:.:: :::.:..::. .: :: :: : CCDS75 VGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAAN 260 270 280 290 300 310 220 230 240 pF1KE0 AAMGAAQGAMNQPQTQYSATPNYTYSNEM :: ::..: CCDS75 AASTAASSAAQNAFKGNQI 320 330 >>CCDS1106.1 SCAMP3 gene_id:10067|Hs108|chr1 (321 aa) initn: 787 init1: 332 opt: 751 Z-score: 946.9 bits: 183.0 E(32554): 2e-46 Smith-Waterman score: 751; 44.9% identity (79.7% similar) in 227 aa overlap (2-227:103-321) 10 20 30 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPP : . ::.::::.: :..:::.::. .:: CCDS11 LLKKQEELNRKAEELDRRERELQHAALGGTATRQNNWPPLPSFCPVQPCFFQDISMEIPQ 80 90 100 110 120 130 40 50 60 70 80 90 pF1KE0 QHVSMTKRLYYLWMLNSVTLAVNLVGCLA-WLIGGGGATNFGLAFLWLILFTPCSYVCWF . . .. .::::: ....: .:...::: . . .....:::..::..::::::.:::. CCDS11 EFQKTVSTMYYLWMCSTLALLLNFLACLASFCVETNNGAGFGLSILWVLLFTPCSFVCWY 140 150 160 170 180 190 100 110 120 130 140 150 pF1KE0 RPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFG ::.::::..::::.:..::: :..: :. ..::.:::::: ::::... CCDS11 RPMYKAFRSDSSFNFFVFFFIFFVQDVLFVLQAIGIPGWGF--------SGWISALVVPK 200 210 220 230 240 160 170 180 190 200 210 pF1KE0 TNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQ : . .:.::. ...:: .::.... :. .:..:: .:.::.:::.:...:...:: :. CCDS11 GNTAVSVLMLLVALLFTGIAVLGIVMLKRIHSLYRRTGASFQKAQQEFAAGVFSNPAVRT 250 260 270 280 290 300 220 230 240 pF1KE0 AAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM :: ::: :::..:. : CCDS11 AAANAAAGAAENAFRAP 310 320 >>CCDS1105.1 SCAMP3 gene_id:10067|Hs108|chr1 (347 aa) initn: 787 init1: 332 opt: 751 Z-score: 946.4 bits: 183.1 E(32554): 2.1e-46 Smith-Waterman score: 751; 44.9% identity (79.7% similar) in 227 aa overlap (2-227:129-347) 10 20 30 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPP : . ::.::::.: :..:::.::. .:: CCDS11 LLKKQEELNRKAEELDRRERELQHAALGGTATRQNNWPPLPSFCPVQPCFFQDISMEIPQ 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE0 QHVSMTKRLYYLWMLNSVTLAVNLVGCLA-WLIGGGGATNFGLAFLWLILFTPCSYVCWF . . .. .::::: ....: .:...::: . . .....:::..::..::::::.:::. CCDS11 EFQKTVSTMYYLWMCSTLALLLNFLACLASFCVETNNGAGFGLSILWVLLFTPCSFVCWY 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE0 RPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFG ::.::::..::::.:..::: :..: :. ..::.:::::: ::::... CCDS11 RPMYKAFRSDSSFNFFVFFFIFFVQDVLFVLQAIGIPGWGF--------SGWISALVVPK 220 230 240 250 260 270 160 170 180 190 200 210 pF1KE0 TNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQ : . .:.::. ...:: .::.... :. .:..:: .:.::.:::.:...:...:: :. CCDS11 GNTAVSVLMLLVALLFTGIAVLGIVMLKRIHSLYRRTGASFQKAQQEFAAGVFSNPAVRT 280 290 300 310 320 330 220 230 240 pF1KE0 AAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM :: ::: :::..:. : CCDS11 AAANAAAGAAENAFRAP 340 >>CCDS10271.1 SCAMP2 gene_id:10066|Hs108|chr15 (329 aa) initn: 744 init1: 308 opt: 747 Z-score: 941.7 bits: 182.1 E(32554): 3.9e-46 Smith-Waterman score: 747; 49.3% identity (81.3% similar) in 219 aa overlap (6-222:118-328) 10 20 30 pF1KE0 MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVS ::.::::.. :.:::::::: ..:: .. CCDS10 QQEELDRKAAELERKERELQNTVANLHVRQNNWPPLPSWCPVKPCFYQDFSTEIPADYQR 90 100 110 120 130 140 40 50 60 70 80 90 pF1KE0 MTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGG-ATNFGLAFLWLILFTPCSYVCWFRPIY . : :::::::.:::: .::..::::. :... ...:::..::...::::...::.:::: CCDS10 ICKMLYYLWMLHSVTLFLNLLACLAWFSGNSSKGVDFGLSILWFLIFTPCAFLCWYRPIY 150 160 170 180 190 200 100 110 120 130 140 150 pF1KE0 KAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCPTLASSCSGWIATISFFGTN-I :::..:.::::..:::.:. :. : ::: ::::: : :::::..: . .. . CCDS10 KAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPGLGD--------SGWIAALSTLDNHSL 210 220 230 240 250 160 170 180 190 200 210 pF1KE0 GSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQ . .:.:.. . .::. ::.: . :. ::..:: .:.::..::::.. : ... ..::. CCDS10 AISVIMMVVAGFFTLCAVLSVFLLQRVHSLYRRTGASFQQAQEEFSQGIFSSRTFHRAAS 260 270 280 290 300 310 220 230 240 pF1KE0 NAAMGAAQGAMNQPQTQYSATPNYTYSNEM .::.:: :: CCDS10 SAAQGAFQGN 320 243 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:44:59 2016 done: Thu Nov 3 23:44:59 2016 Total Scan time: 2.150 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]