Result of FASTA (omim) for pF1KE0156
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0156, 261 aa
  1>>>pF1KE0156 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5944+/-0.000336; mu= 19.6097+/- 0.021
 mean_var=73.3448+/-14.415, 0's: 0 Z-trim(115.9): 121  B-trim: 156 in 1/52
 Lambda= 0.149758
 statistics sampled from 26628 (26757) to 26628 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.314), width:  16
 Scan time:  7.340

The best scores are:                                      opt bits E(85289)
NP_055049 (OMIM: 601417) estradiol 17-beta-dehydro ( 261) 1685 372.9 3.3e-103
NP_004484 (OMIM: 300220,300256,300438) 3-hydroxyac ( 261)  374 89.6 6.2e-18
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278)  369 88.6 1.4e-17
NP_000405 (OMIM: 233400,261515,601860) peroxisomal ( 736)  342 83.2 1.5e-15
XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  313 76.5 6.7e-14
XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  313 76.5 6.7e-14
XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  313 76.5 6.7e-14
NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reduct ( 326)  313 76.5 6.7e-14
NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase ( 335)  313 76.5 6.8e-14
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303)  303 74.3 2.8e-13
NP_001182147 (OMIM: 260800,608347) L-xylulose redu ( 242)  299 73.4 4.4e-13
NP_057370 (OMIM: 260800,608347) L-xylulose reducta ( 244)  299 73.4 4.4e-13
NP_001269917 (OMIM: 611596) dehydrogenase/reductas ( 244)  277 68.6 1.2e-11
NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-C ( 292)  274 68.1 2.1e-11
NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid de ( 270)  272 67.6 2.7e-11
NP_001032900 (OMIM: 300220,300256,300438) 3-hydrox ( 252)  271 67.3   3e-11
NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260)  271 67.3 3.1e-11
NP_001278956 (OMIM: 233400,261515,601860) peroxiso ( 712)  272 68.0 5.3e-11
NP_001186221 (OMIM: 233400,261515,601860) peroxiso ( 718)  272 68.0 5.3e-11
NP_001186220 (OMIM: 233400,261515,601860) peroxiso ( 761)  272 68.0 5.5e-11
XP_005250865 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 243)  258 64.5 2.1e-10
XP_011534640 (OMIM: 615194) PREDICTED: dehydrogena ( 204)  254 63.6 3.3e-10
XP_011534641 (OMIM: 615194) PREDICTED: dehydrogena ( 204)  254 63.6 3.3e-10
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  254 63.7 4.1e-10
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280)  254 63.7 4.1e-10
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  254 63.7 4.1e-10
XP_006720309 (OMIM: 615195) PREDICTED: putative de ( 244)  252 63.2 5.1e-10
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309)  238 60.3 4.9e-09
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318)  238 60.3   5e-09
NP_001129522 (OMIM: 610410) dehydrogenase/reductas ( 313)  228 58.1 2.2e-08
NP_612461 (OMIM: 610410) dehydrogenase/reductase S ( 313)  228 58.1 2.2e-08
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310)  225 57.5 3.4e-08
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325)  225 57.5 3.5e-08
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325)  225 57.5 3.5e-08
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334)  225 57.5 3.6e-08
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372)  225 57.6 3.9e-08
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372)  225 57.6 3.9e-08
NP_001264793 (OMIM: 615195) putative dehydrogenase ( 150)  215 55.0 9.2e-08
XP_005257715 (OMIM: 616159) PREDICTED: dehydrogena ( 229)  214 55.0 1.4e-07
NP_000851 (OMIM: 119900,259100,601688) 15-hydroxyp ( 266)  210 54.2 2.9e-07
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232)  205 53.0 5.6e-07
XP_011509780 (OMIM: 605843) PREDICTED: peroxisomal ( 157)  200 51.8   9e-07
XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324)  193 50.6 4.2e-06
XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324)  193 50.6 4.2e-06
XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  193 50.6 4.3e-06
XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  193 50.6 4.3e-06
XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330)  193 50.6 4.3e-06
NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343)  193 50.6 4.4e-06
XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343)  193 50.6 4.4e-06
XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343)  193 50.6 4.4e-06


>>NP_055049 (OMIM: 601417) estradiol 17-beta-dehydrogena  (261 aa)
 initn: 1685 init1: 1685 opt: 1685  Z-score: 1973.8  bits: 372.9 E(85289): 3.3e-103
Smith-Waterman score: 1685; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)

               10        20        30        40        50        60
pF1KE0 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL
              190       200       210       220       230       240

              250       260 
pF1KE0 ASEDSGYITGTSVEVTGGLFM
       :::::::::::::::::::::
NP_055 ASEDSGYITGTSVEVTGGLFM
              250       260 

>>NP_004484 (OMIM: 300220,300256,300438) 3-hydroxyacyl-C  (261 aa)
 initn: 324 init1: 240 opt: 374  Z-score: 443.0  bits: 89.6 E(85289): 6.2e-18
Smith-Waterman score: 413; 30.8% identity (65.4% similar) in 266 aa overlap (9-261:8-259)

               10        20        30        40        50        60
pF1KE0 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS
               ... .:..::..::.: :.. ::.:.::...  ::  ....  .. ::    
NP_004  MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG----
                10        20        30        40        50         

               70         80        90       100       110         
pF1KE0 KEGPPRGNHAAFQ-ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE--
              :. .:  :::.  . ..  :  ... :.:  .:.:.::::.      ....  
NP_004 -------NNCVFAPADVTSEKDVQTALALAKGKFGRV-DVAVNCAGIAVASKTYNLKKGQ
                 60        70        80         90       100       

           120       130       140            150       160        
pF1KE0 ----DDWDKVIAVNLKGTFLVTQAAAQALVSN-----GCRGSIINISSIVGKVGNVGQTN
           .:...:. ::: ::: : . .:  . .:     : :: ::: .:...  :.:::. 
NP_004 THTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAA
       110       120       130       140       150       160       

      170       180       190       200       210       220        
pF1KE0 YAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHL
       :.:::.:..:.:   ::.:.  :::  .. ::...::.  ..:.:: . .. ..:. ..:
NP_004 YSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRL
       170       180       190       200       210       220       

       230       240       250       260   
pF1KE0 GDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM  
       ::: . : .:  .   .. ...:  ... :.. :  
NP_004 GDPAEYAHLVQAII--ENPFLNGEVIRLDGAIRMQP
       230       240         250       260 

>>NP_066284 (OMIM: 611596) dehydrogenase/reductase SDR f  (278 aa)
 initn: 369 init1: 138 opt: 369  Z-score: 436.8  bits: 88.6 E(85289): 1.4e-17
Smith-Waterman score: 369; 32.6% identity (64.4% similar) in 267 aa overlap (1-258:19-273)

                                    10        20        30         
pF1KE0                   MASQLQNR---LRSALALVTGAGSGIGRAVSVRLAGEGATVA
                         :::. ..:   : . .::::.. .::: :.. ::: .:: :.
NP_066 MHKAGLLGLCARAWNSVRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVV
               10        20        30        40        50        60

      40        50         60        70        80        90        
pF1KE0 ACDLDRAAAQETVRLLGGPG-SKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPS
       . .  .  ....:  : : : :  :      .. ..  .: :  : .   :.  .    .
NP_066 VSSRKQQNVDQAVATLQGEGLSVTG------TVCHVGKAEDRE-RLVATAVK--LHGGID
               70        80              90        100         110 

      100       110          120       130       140       150     
pF1KE0 VVVSCAGITQDEF---LLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINIS
       ..:: :..  . :   .. ..:. :::.. .:.:.  :.:.:..  . . :  ::.. .:
NP_066 ILVSNAAV--NPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGG-GSVVIVS
               120       130       140       150       160         

         160       170       180       190       200       210     
pF1KE0 SIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQK
       ::..   . : . : .::....:::.: : ::. ..:: : . ::.: : ... .   ..
NP_066 SIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKE
      170       180       190       200       210       220        

           220       230       240       250       260   
pF1KE0 VVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM  
         ... : . . .::.::: : .:.:: :::..:::: .: : ::     
NP_066 KEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL
      230       240       250       260       270        

>>NP_000405 (OMIM: 233400,261515,601860) peroxisomal mul  (736 aa)
 initn: 365 init1: 145 opt: 342  Z-score: 400.1  bits: 83.2 E(85289): 1.5e-15
Smith-Waterman score: 357; 34.2% identity (62.0% similar) in 263 aa overlap (1-260:1-237)

               10        20        30        40          50        
pF1KE0 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL--DRAAAQETVRLLGGP
       :.: :  :. . ..::::::.:.::: .. .: .:: :.. ::  :  .. .   : .  
NP_000 MGSPL--RFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKG-SLAADK
                 10        20        30        40        50        

       60        70        80        90       100       110        
pF1KE0 GSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSED
         .:   ::..:.  :. . .. .. ... .   :.:  .:::. ::: .:. . ..:..
NP_000 VVEEIRRRGGKAV--ANYDSVEEGEKVVKTALDAFGRI-DVVVNNAGILRDRSFARISDE
        60        70          80        90        100       110    

      120       130       140       150       160       170        
pF1KE0 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG
       ::: .  :.:.:.: ::.:: . . ..   : ::  ::  :  :: ::.::.:.: :..:
NP_000 DWDIIHRVHLRGSFQVTRAAWEHMKKQK-YGRIIMTSSASGIYGNFGQANYSAAKLGLLG
          120       130       140        150       160       170   

      180       190       200       210        220       230       
pF1KE0 LTQTAARELGRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVADVV
       :... : :  . .:.::.. :.  .. ::: : :. .:. .           :: :: .:
NP_000 LANSLAIEGRKSNIHCNTIAPN-AGSRMTQTVMPEDLVEALK----------PEYVAPLV
           180       190        200       210                 220  

       240       250       260                                     
pF1KE0 AFLASEDSGYITGTSVEVTGGLFM                                    
        .:  :        : : .::::                                     
NP_000 LWLCHE--------SCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK
                    230       240       250       260       270    

>>XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 243 init1: 156 opt: 313  Z-score: 370.6  bits: 76.5 E(85289): 6.7e-14
Smith-Waterman score: 313; 26.4% identity (62.4% similar) in 258 aa overlap (7-258:46-293)

                                       10        20        30      
pF1KE0                         MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGA
                                     : ... .:..::.:.:.:..... :.. ::
XP_016 FSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA
          20        30        40        50        60        70     

         40        50        60        70         80        90     
pF1KE0 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-AFQADVSEARAARCLLEQVQACFSR
           :    . :.. . .: . . . .   ::.. :.: :: .   ..  . ..    ..
XP_016 Q---C----VIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGH
                 80        90       100       110       120        

         100         110       120       130       140       150   
pF1KE0 PPSVVVSCAG--ITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIIN
       :  :. . ::  :.  :   ..: . :  .  . :.:: .::   .. :..    .....
XP_016 PNIVINNAAGNFISPTE---RLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLS
      130       140          150       160       170       180     

           160       170       180       190       200         210 
pF1KE0 ISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP--MTQKVP
       :..: ...:.   .  :..:::: ..... : : :..:.: : . :: : :   ...  :
XP_016 ITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDP
         190       200       210       220       230       240     

              220       230       240       250       260          
pF1KE0 QKVVDK-ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM         
         . .: .   :: :.::  :..:...::: :. ...:.:. ..  ::            
XP_016 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

XP_016 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 243 init1: 156 opt: 313  Z-score: 370.6  bits: 76.5 E(85289): 6.7e-14
Smith-Waterman score: 313; 26.4% identity (62.4% similar) in 258 aa overlap (7-258:46-293)

                                       10        20        30      
pF1KE0                         MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGA
                                     : ... .:..::.:.:.:..... :.. ::
XP_016 FSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA
          20        30        40        50        60        70     

         40        50        60        70         80        90     
pF1KE0 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-AFQADVSEARAARCLLEQVQACFSR
           :    . :.. . .: . . . .   ::.. :.: :: .   ..  . ..    ..
XP_016 Q---C----VIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGH
                 80        90       100       110       120        

         100         110       120       130       140       150   
pF1KE0 PPSVVVSCAG--ITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIIN
       :  :. . ::  :.  :   ..: . :  .  . :.:: .::   .. :..    .....
XP_016 PNIVINNAAGNFISPTE---RLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLS
      130       140          150       160       170       180     

           160       170       180       190       200         210 
pF1KE0 ISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP--MTQKVP
       :..: ...:.   .  :..:::: ..... : : :..:.: : . :: : :   ...  :
XP_016 ITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDP
         190       200       210       220       230       240     

              220       230       240       250       260          
pF1KE0 QKVVDK-ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM         
         . .: .   :: :.::  :..:...::: :. ...:.:. ..  ::            
XP_016 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

XP_016 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 243 init1: 156 opt: 313  Z-score: 370.6  bits: 76.5 E(85289): 6.7e-14
Smith-Waterman score: 313; 26.4% identity (62.4% similar) in 258 aa overlap (7-258:46-293)

                                       10        20        30      
pF1KE0                         MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGA
                                     : ... .:..::.:.:.:..... :.. ::
XP_011 FSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA
          20        30        40        50        60        70     

         40        50        60        70         80        90     
pF1KE0 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-AFQADVSEARAARCLLEQVQACFSR
           :    . :.. . .: . . . .   ::.. :.: :: .   ..  . ..    ..
XP_011 Q---C----VIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGH
                 80        90       100       110       120        

         100         110       120       130       140       150   
pF1KE0 PPSVVVSCAG--ITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIIN
       :  :. . ::  :.  :   ..: . :  .  . :.:: .::   .. :..    .....
XP_011 PNIVINNAAGNFISPTE---RLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLS
      130       140          150       160       170       180     

           160       170       180       190       200         210 
pF1KE0 ISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP--MTQKVP
       :..: ...:.   .  :..:::: ..... : : :..:.: : . :: : :   ...  :
XP_011 ITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDP
         190       200       210       220       230       240     

              220       230       240       250       260          
pF1KE0 QKVVDK-ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM         
         . .: .   :: :.::  :..:...::: :. ...:.:. ..  ::            
XP_011 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

XP_011 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reductase,  (326 aa)
 initn: 243 init1: 156 opt: 313  Z-score: 370.6  bits: 76.5 E(85289): 6.7e-14
Smith-Waterman score: 313; 26.4% identity (62.4% similar) in 258 aa overlap (7-258:46-293)

                                       10        20        30      
pF1KE0                         MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGA
                                     : ... .:..::.:.:.:..... :.. ::
NP_001 FSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA
          20        30        40        50        60        70     

         40        50        60        70         80        90     
pF1KE0 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-AFQADVSEARAARCLLEQVQACFSR
           :    . :.. . .: . . . .   ::.. :.: :: .   ..  . ..    ..
NP_001 Q---C----VIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGH
                 80        90       100       110       120        

         100         110       120       130       140       150   
pF1KE0 PPSVVVSCAG--ITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIIN
       :  :. . ::  :.  :   ..: . :  .  . :.:: .::   .. :..    .....
NP_001 PNIVINNAAGNFISPTE---RLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLS
      130       140          150       160       170       180     

           160       170       180       190       200         210 
pF1KE0 ISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP--MTQKVP
       :..: ...:.   .  :..:::: ..... : : :..:.: : . :: : :   ...  :
NP_001 ITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDP
         190       200       210       220       230       240     

              220       230       240       250       260          
pF1KE0 QKVVDK-ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM         
         . .: .   :: :.::  :..:...::: :. ...:.:. ..  ::            
NP_001 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
         250       260       270       280       290       300     

NP_001 RKVTKEQWDTIEELIRKTKGS
         310       320      

>>NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase, mi  (335 aa)
 initn: 243 init1: 156 opt: 313  Z-score: 370.4  bits: 76.5 E(85289): 6.8e-14
Smith-Waterman score: 313; 26.4% identity (62.4% similar) in 258 aa overlap (7-258:55-302)

                                       10        20        30      
pF1KE0                         MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGA
                                     : ... .:..::.:.:.:..... :.. ::
NP_001 FSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA
           30        40        50        60        70        80    

         40        50        60        70         80        90     
pF1KE0 TVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA-AFQADVSEARAARCLLEQVQACFSR
           :    . :.. . .: . . . .   ::.. :.: :: .   ..  . ..    ..
NP_001 Q---C----VIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGH
                  90       100       110       120       130       

         100         110       120       130       140       150   
pF1KE0 PPSVVVSCAG--ITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIIN
       :  :. . ::  :.  :   ..: . :  .  . :.:: .::   .. :..    .....
NP_001 PNIVINNAAGNFISPTE---RLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLS
       140       150          160       170       180       190    

           160       170       180       190       200         210 
pF1KE0 ISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATP--MTQKVP
       :..: ...:.   .  :..:::: ..... : : :..:.: : . :: : :   ...  :
NP_001 ITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDP
          200       210       220       230       240       250    

              220       230       240       250       260          
pF1KE0 QKVVDK-ITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM         
         . .: .   :: :.::  :..:...::: :. ...:.:. ..  ::            
NP_001 TGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDL
          260       270       280       290       300       310    

NP_001 RKVTKEQWDTIEELIRKTKGS
          320       330     

>>NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl-CoA  (303 aa)
 initn: 266 init1: 118 opt: 303  Z-score: 359.3  bits: 74.3 E(85289): 2.8e-13
Smith-Waterman score: 303; 31.3% identity (59.5% similar) in 262 aa overlap (9-258:16-264)

                      10        20        30          40           
pF1KE0        MASQLQNRLRSALALVTGAGSGIGRAVSVRLA--GEGATVAACDLDR--AAAQ
                      :.. .:.:::...:::.:.  .:   : ....:.  :.:  .::.
NP_060 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KE0 ETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQD
       :    :  : .:.    .    .: .. . . .  :....   :..   .: . .:    
NP_060 ELQANL--PPTKQ----ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGG----
                 70            80        90       100       110    

     110          120       130       140        150       160     
pF1KE0 EFLL---HMSEDDWDKVIAVNLKGTFLVTQAAAQALVS-NGCRGSIINISSIVGKVGNVG
       .::    :.:   :  :. .:: ::: . .:. .. .. .:  :::.::  .  :.:   
NP_060 QFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG--GSIVNII-VPTKAGFPL
              120       130       140       150          160       

         170       180       190       200           210       220 
pF1KE0 QTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFI----ATPMTQKVPQKVVDKITEM
        .. .:..::: .::.. : : .  ::: : : :: :    :.    .  :.  .   . 
NP_060 AVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK
       170       180       190       200       210       220       

             230       240       250       260                     
pF1KE0 IPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM                    
       ::  ..: ::.:..:: :: :  ...::: ::.: ::                       
NP_060 IPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDL
       230       240       250       260       270       280       

NP_060 SVVKKMKETFKEKAKL
       290       300   




261 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:38:53 2016 done: Thu Nov  3 23:38:54 2016
 Total Scan time:  7.340 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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