FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0161, 265 aa 1>>>pF1KE0161 265 - 265 aa - 265 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2130+/-0.000833; mu= 15.5051+/- 0.050 mean_var=64.8709+/-13.316, 0's: 0 Z-trim(106.1): 23 B-trim: 0 in 0/50 Lambda= 0.159239 statistics sampled from 8763 (8781) to 8763 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.27), width: 16 Scan time: 2.060 The best scores are: opt bits E(32554) CCDS46860.1 SYNPR gene_id:132204|Hs108|chr3 ( 265) 1777 416.8 7.7e-117 CCDS46859.1 SYNPR gene_id:132204|Hs108|chr3 ( 285) 1717 403.0 1.2e-112 CCDS14321.1 SYP gene_id:6855|Hs108|chrX ( 313) 1000 238.4 4.8e-63 CCDS41365.1 SYPL2 gene_id:284612|Hs108|chr1 ( 272) 746 180.0 1.6e-45 CCDS47685.1 SYPL1 gene_id:6856|Hs108|chr7 ( 241) 622 151.4 5.3e-37 CCDS5736.1 SYPL1 gene_id:6856|Hs108|chr7 ( 259) 622 151.5 5.7e-37 >>CCDS46860.1 SYNPR gene_id:132204|Hs108|chr3 (265 aa) initn: 1777 init1: 1777 opt: 1777 Z-score: 2211.1 bits: 416.8 E(32554): 7.7e-117 Smith-Waterman score: 1777; 100.0% identity (100.0% similar) in 265 aa overlap (1-265:1-265) 10 20 30 40 50 60 pF1KE0 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQ 190 200 210 220 230 240 250 260 pF1KE0 QASLGPTSDEFGQQPTGPTSFTNQI ::::::::::::::::::::::::: CCDS46 QASLGPTSDEFGQQPTGPTSFTNQI 250 260 >>CCDS46859.1 SYNPR gene_id:132204|Hs108|chr3 (285 aa) initn: 1717 init1: 1717 opt: 1717 Z-score: 2136.2 bits: 403.0 E(32554): 1.2e-112 Smith-Waterman score: 1717; 100.0% identity (100.0% similar) in 257 aa overlap (9-265:29-285) 10 20 30 40 pF1KE0 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS :::::::::::::::::::::::::::::::: CCDS46 MDPVSQLASAGTFRVLKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 IDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 IFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 PSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSS 190 200 210 220 230 240 230 240 250 260 pF1KE0 SYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI ::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI 250 260 270 280 >>CCDS14321.1 SYP gene_id:6855|Hs108|chrX (313 aa) initn: 775 init1: 675 opt: 1000 Z-score: 1245.4 bits: 238.4 E(32554): 4.8e-63 Smith-Waterman score: 1038; 58.4% identity (78.6% similar) in 281 aa overlap (9-265:35-313) 10 20 30 pF1KE0 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESN .::::::::::.::: :.:::::.:::::. CCDS14 ADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 LSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATV :::.. : :::::::: :..:::.: :. :.:: ::::::::::::::::::..: . CCDS14 LSIEVEFEYPFRLHQVYFDAPTCRGGTT-KVFLVGDYSSSAEFFVTVAVFAFLYSMGALA 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 VYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSAC .:::.::::::::.::..::..:.::.:.:::.::::::::::::.::::.... : .: CCDS14 TYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVC 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE0 KQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKH .: .: : ...:: :.:::::::::::..::.::.::::::::: . : ::. CCDS14 RQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQ 190 200 210 220 230 240 220 230 240 250 pF1KE0 --------SSSYNQG--GYN-QDSYGSSSGY---------SQQASLGPTSDEFGQQ---P ...:.:: ::. ::::: ..:: : .. :: .: .::: : CCDS14 PAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGD-YGQQGYGP 250 260 270 280 290 300 260 pF1KE0 TG-PTSFTNQI : ::::.::. CCDS14 QGAPTSFSNQM 310 >>CCDS41365.1 SYPL2 gene_id:284612|Hs108|chr1 (272 aa) initn: 548 init1: 548 opt: 746 Z-score: 930.9 bits: 180.0 E(32554): 1.6e-45 Smith-Waterman score: 746; 48.1% identity (73.6% similar) in 235 aa overlap (9-241:44-272) 10 20 30 pF1KE0 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESN :::::::..::.::: : : :.... CCDS41 SPRQQVDRLLVGLRWRRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDV 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE0 LSIDIAFAYPFRLHQVTFEVPTCEGKERQK-LALIGDSSSSAEFFVTVAVFAFLYSLAAT :: .::.::::::.. .:.: :. . .: . :.:: :. ::::::...:.:.:..:: CCDS41 SSIIVAFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAAL 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE0 VVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSA :.:. :.: : ::.: ::.:: ::: :.:.:::...::.:::.::: :: :. . ::. CCDS41 VIYLRFHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSV 140 150 160 170 180 190 160 170 180 190 200 210 pF1KE0 CKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEK :. : : .: :. : ::.:::.::.::::: ::::::: ::..:: .: CCDS41 CHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQD---- 200 210 220 230 240 220 230 240 250 260 pF1KE0 HSSSYNQG-GYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI .. .:: : .:.: . ... .: CCDS41 --QDQDQGQGPSQESAAEQGAVEKQ 250 260 270 >>CCDS47685.1 SYPL1 gene_id:6856|Hs108|chr7 (241 aa) initn: 646 init1: 301 opt: 622 Z-score: 777.7 bits: 151.4 E(32554): 5.3e-37 Smith-Waterman score: 623; 44.5% identity (71.8% similar) in 220 aa overlap (11-226:26-234) 10 20 30 40 pF1KE0 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAF .:::::::::..: ...:.: . : .. .: CCDS47 MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 AYPFRLHQVTFEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYI .:::::....:. : :. . .. .:::: ::::.:.:: :::.::: .:: ..:. CCDS47 GYPFRLNEASFQPPPGVNICDVNWKD-YVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYV 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 FFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQP . . : .. . :.:::.::.: .:::::..:::::.:.:.:.:: .... . ::. CCDS47 GYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 SNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSS . :. :.:::.::.:::::.:::.:: :::.:::. :: :. :: CCDS47 AVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSP-----SNTSAPHS-- 180 190 200 210 220 230 230 240 250 260 pF1KE0 YNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI ::: CCDS47 --QGGIPPPTGI 240 >>CCDS5736.1 SYPL1 gene_id:6856|Hs108|chr7 (259 aa) initn: 629 init1: 301 opt: 622 Z-score: 777.3 bits: 151.5 E(32554): 5.7e-37 Smith-Waterman score: 623; 44.5% identity (71.8% similar) in 220 aa overlap (11-226:44-252) 10 20 30 40 pF1KE0 MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS .:::::::::..: ...:.: . : . CCDS57 RLGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKT 20 30 40 50 60 70 50 60 70 80 90 pF1KE0 IDIAFAYPFRLHQVTFEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAA . .:.:::::....:. : :. . .. .:::: ::::.:.:: :::.::: .:: CCDS57 VTATFGYPFRLNEASFQPPPGVNICDVNWKD-YVLIGDYSSSAQFYVTFAVFVFLYCIAA 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE0 TVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMS ..:. . . : .. . :.:::.::.: .:::::..:::::.:.:.:.:: .... . CCDS57 LLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELP 140 150 160 170 180 190 160 170 180 190 200 210 pF1KE0 ACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPME ::. . :. :.:::.::.:::::.:::.:: :::.:::. :: :. CCDS57 PCKKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSP-----SNTSA 200 210 220 230 240 220 230 240 250 260 pF1KE0 KHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI :: ::: CCDS57 PHS----QGGIPPPTGI 250 265 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:23:05 2016 done: Thu Nov 3 23:23:05 2016 Total Scan time: 2.060 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]