FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0164, 138 aa 1>>>pF1KE0164 138 - 138 aa - 138 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1130+/-0.000342; mu= 7.5815+/- 0.021 mean_var=80.0729+/-15.612, 0's: 0 Z-trim(115.8): 7 B-trim: 40 in 1/53 Lambda= 0.143328 statistics sampled from 26503 (26510) to 26503 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.311), width: 16 Scan time: 4.110 The best scores are: opt bits E(85289) NP_116211 (OMIM: 616275) protein FAM136A isoform 1 ( 138) 910 197.1 7.5e-51 NP_001316682 (OMIM: 616275) protein FAM136A isofor ( 223) 747 163.5 1.6e-40 NP_001316681 (OMIM: 616275) protein FAM136A isofor ( 245) 746 163.3 2e-40 NP_001316687 (OMIM: 616275) protein FAM136A isofor ( 107) 726 159.0 1.7e-39 NP_001316684 (OMIM: 616275) protein FAM136A isofor ( 107) 726 159.0 1.7e-39 NP_001316686 (OMIM: 616275) protein FAM136A isofor ( 107) 726 159.0 1.7e-39 >>NP_116211 (OMIM: 616275) protein FAM136A isoform 1 [Ho (138 aa) initn: 910 init1: 910 opt: 910 Z-score: 1033.9 bits: 197.1 E(85289): 7.5e-51 Smith-Waterman score: 910; 98.6% identity (99.3% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KE0 MAELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVP :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_116 MAELQQLRVQEAVESMVKSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 LAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMH 70 80 90 100 110 120 130 pF1KE0 LIPTMTKKMKEAPLSIGK :::::::::::: ::::: NP_116 LIPTMTKKMKEALLSIGK 130 >>NP_001316682 (OMIM: 616275) protein FAM136A isoform 3 (223 aa) initn: 747 init1: 747 opt: 747 Z-score: 848.5 bits: 163.5 E(85289): 1.6e-40 Smith-Waterman score: 747; 97.3% identity (98.2% similar) in 112 aa overlap (27-138:112-223) 10 20 30 40 50 pF1KE0 MAELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIER . :::::::::::::::::::::::::::: NP_001 GSFGGSDEIRVPLPCARLFSAPSSPGQERPRRQGLMFRCSASCCEDSQASMKQVHQCIER 90 100 110 120 130 140 60 70 80 90 100 110 pF1KE0 CHVPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CHVPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVD 150 160 170 180 190 200 120 130 pF1KE0 DHMHLIPTMTKKMKEAPLSIGK :::::::::::::::: ::::: NP_001 DHMHLIPTMTKKMKEALLSIGK 210 220 >-- initn: 190 init1: 171 opt: 171 Z-score: 204.8 bits: 44.4 E(85289): 0.00011 Smith-Waterman score: 171; 96.6% identity (100.0% similar) in 29 aa overlap (1-29:1-29) 10 20 30 40 50 60 pF1KE0 MAELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVP :::::::::::::::::.::::::::::: NP_001 MAELQQLRVQEAVESMVKSLERENIRKMQVAGLGPNQDPLLSGWVPGPSLSHHATPCTAA 10 20 30 40 50 60 >>NP_001316681 (OMIM: 616275) protein FAM136A isoform 2 (245 aa) initn: 746 init1: 746 opt: 746 Z-score: 846.7 bits: 163.3 E(85289): 2e-40 Smith-Waterman score: 746; 99.1% identity (99.1% similar) in 110 aa overlap (29-138:136-245) 10 20 30 40 50 pF1KE0 MAELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCH :::::::::::::::::::::::::::::: NP_001 PGQERPRRQVGSPWWQALAPPPSPLTRPLPQGLMFRCSASCCEDSQASMKQVHQCIERCH 110 120 130 140 150 160 60 70 80 90 100 110 pF1KE0 VPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDH 170 180 190 200 210 220 120 130 pF1KE0 MHLIPTMTKKMKEAPLSIGK :::::::::::::: ::::: NP_001 MHLIPTMTKKMKEALLSIGK 230 240 >-- initn: 190 init1: 171 opt: 171 Z-score: 204.2 bits: 44.4 E(85289): 0.00012 Smith-Waterman score: 171; 96.6% identity (100.0% similar) in 29 aa overlap (1-29:1-29) 10 20 30 40 50 60 pF1KE0 MAELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVP :::::::::::::::::.::::::::::: NP_001 MAELQQLRVQEAVESMVKSLERENIRKMQVAGLGPNQDPLLSGWVPGPSLSHHATPCTAA 10 20 30 40 50 60 >>NP_001316687 (OMIM: 616275) protein FAM136A isoform 4 (107 aa) initn: 726 init1: 726 opt: 726 Z-score: 830.0 bits: 159.0 E(85289): 1.7e-39 Smith-Waterman score: 726; 99.1% identity (99.1% similar) in 107 aa overlap (32-138:1-107) 10 20 30 40 50 60 pF1KE0 AELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVPL :::::::::::::::::::::::::::::: NP_001 MFRCSASCCEDSQASMKQVHQCIERCHVPL 10 20 30 70 80 90 100 110 120 pF1KE0 AQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMHL 40 50 60 70 80 90 130 pF1KE0 IPTMTKKMKEAPLSIGK ::::::::::: ::::: NP_001 IPTMTKKMKEALLSIGK 100 >>NP_001316684 (OMIM: 616275) protein FAM136A isoform 4 (107 aa) initn: 726 init1: 726 opt: 726 Z-score: 830.0 bits: 159.0 E(85289): 1.7e-39 Smith-Waterman score: 726; 99.1% identity (99.1% similar) in 107 aa overlap (32-138:1-107) 10 20 30 40 50 60 pF1KE0 AELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVPL :::::::::::::::::::::::::::::: NP_001 MFRCSASCCEDSQASMKQVHQCIERCHVPL 10 20 30 70 80 90 100 110 120 pF1KE0 AQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMHL 40 50 60 70 80 90 130 pF1KE0 IPTMTKKMKEAPLSIGK ::::::::::: ::::: NP_001 IPTMTKKMKEALLSIGK 100 >>NP_001316686 (OMIM: 616275) protein FAM136A isoform 4 (107 aa) initn: 726 init1: 726 opt: 726 Z-score: 830.0 bits: 159.0 E(85289): 1.7e-39 Smith-Waterman score: 726; 99.1% identity (99.1% similar) in 107 aa overlap (32-138:1-107) 10 20 30 40 50 60 pF1KE0 AELQQLRVQEAVESMVRSLERENIRKMQGLMFRCSASCCEDSQASMKQVHQCIERCHVPL :::::::::::::::::::::::::::::: NP_001 MFRCSASCCEDSQASMKQVHQCIERCHVPL 10 20 30 70 80 90 100 110 120 pF1KE0 AQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVKQQLDSCVTKCVDDHMHL 40 50 60 70 80 90 130 pF1KE0 IPTMTKKMKEAPLSIGK ::::::::::: ::::: NP_001 IPTMTKKMKEALLSIGK 100 138 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:13:35 2016 done: Thu Nov 3 23:13:36 2016 Total Scan time: 4.110 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]