FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0165, 187 aa 1>>>pF1KE0165 187 - 187 aa - 187 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3230+/-0.000858; mu= 8.6497+/- 0.051 mean_var=91.5822+/-18.063, 0's: 0 Z-trim(108.6): 20 B-trim: 81 in 2/49 Lambda= 0.134020 statistics sampled from 10335 (10344) to 10335 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.318), width: 16 Scan time: 1.560 The best scores are: opt bits E(32554) CCDS1411.1 TNNI1 gene_id:7135|Hs108|chr1 ( 187) 1198 241.1 2.9e-64 CCDS42628.1 TNNI3 gene_id:7137|Hs108|chr19 ( 210) 706 146.0 1.4e-35 CCDS31333.1 TNNI2 gene_id:7136|Hs108|chr11 ( 182) 684 141.8 2.4e-34 CCDS53594.1 TNNI2 gene_id:7136|Hs108|chr11 ( 182) 682 141.4 3.1e-34 >>CCDS1411.1 TNNI1 gene_id:7135|Hs108|chr1 (187 aa) initn: 1198 init1: 1198 opt: 1198 Z-score: 1267.2 bits: 241.1 E(32554): 2.9e-64 Smith-Waterman score: 1198; 99.5% identity (99.5% similar) in 187 aa overlap (1-187:1-187) 10 20 30 40 50 60 pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS14 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDA 130 140 150 160 170 180 pF1KE0 AKSPTSQ ::::::: CCDS14 AKSPTSQ >>CCDS42628.1 TNNI3 gene_id:7137|Hs108|chr19 (210 aa) initn: 708 init1: 584 opt: 706 Z-score: 752.3 bits: 146.0 E(32554): 1.4e-35 Smith-Waterman score: 706; 62.6% identity (82.1% similar) in 179 aa overlap (2-180:33-210) 10 20 30 pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWE :....: ::.::::: ::.:.: ::. : CCDS42 DGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 QEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNT .: :::..:: : :. : :. ::... ::::::.:::.:. ::::::::::: .: CCDS42 REAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNI 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 REIKDLKLKVMALRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTE :: :: :.. :::::::: :::::.:::::..::::.. : :.::::.::.::::::: CCDS42 TEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTE 130 140 150 160 170 180 160 170 180 pF1KE0 KERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ :: ::::::::..:.:::::::: :.. CCDS42 KENR-EVGDWRKNIDALSGMEGRKKKFES 190 200 210 >>CCDS31333.1 TNNI2 gene_id:7136|Hs108|chr11 (182 aa) initn: 570 init1: 448 opt: 684 Z-score: 730.3 bits: 141.8 E(32554): 2.4e-34 Smith-Waterman score: 684; 58.0% identity (82.9% similar) in 181 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS : . :.. . ..:. :::.:: : :.:. .::::: ::::. : :. : :.: CCDS31 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA .:.::..::::.....::.::.:.. ....:..:.. :.. ::::::::::::::.:: CCDS31 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA 60 70 80 90 100 110 130 140 150 160 170 pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD ::::.::::::::: ::::::::.:::::::::: . .:::::::.: ::::::::::. CCDS31 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE 120 130 140 150 160 170 180 pF1KE0 AAKSPTSQ . CCDS31 SES 180 >>CCDS53594.1 TNNI2 gene_id:7136|Hs108|chr11 (182 aa) initn: 570 init1: 448 opt: 682 Z-score: 728.2 bits: 141.4 E(32554): 3.1e-34 Smith-Waterman score: 682; 57.5% identity (82.9% similar) in 181 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS : . ... . ..:. :::.:: : :.:. .::::: ::::. : :. : :.: CCDS53 MSQCKKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA .:.::..::::.....::.::.:.. ....:..:.. :.. ::::::::::::::.:: CCDS53 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA 60 70 80 90 100 110 130 140 150 160 170 pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD ::::.::::::::: ::::::::.:::::::::: . .:::::::.: ::::::::::. CCDS53 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE 120 130 140 150 160 170 180 pF1KE0 AAKSPTSQ . CCDS53 SES 180 187 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:12:10 2016 done: Thu Nov 3 23:12:11 2016 Total Scan time: 1.560 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]