FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0165, 187 aa
  1>>>pF1KE0165 187 - 187 aa - 187 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0891+/-0.000347; mu= 10.1392+/- 0.022
 mean_var=100.4784+/-19.568, 0's: 0 Z-trim(116.0): 25  B-trim: 183 in 1/53
 Lambda= 0.127949
 statistics sampled from 26860 (26880) to 26860 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.315), width:  16
 Scan time:  5.360

The best scores are:                                      opt bits E(85289)
NP_003272 (OMIM: 191042) troponin I, slow skeletal ( 187) 1198 231.0 8.8e-61
NP_000354 (OMIM: 115210,191044,611880,613286,61369 ( 210)  706 140.2 2.1e-33
NP_003273 (OMIM: 191043,601680) troponin I, fast s ( 182)  684 136.1 3.1e-32
NP_001139301 (OMIM: 191043,601680) troponin I, fas ( 182)  684 136.1 3.1e-32
NP_001139313 (OMIM: 191043,601680) troponin I, fas ( 182)  682 135.7   4e-32


>>NP_003272 (OMIM: 191042) troponin I, slow skeletal mus  (187 aa)
 initn: 1198 init1: 1198 opt: 1198  Z-score: 1212.3  bits: 231.0 E(85289): 8.8e-61
Smith-Waterman score: 1198; 99.5% identity (99.5% similar) in 187 aa overlap (1-187:1-187)

               10        20        30        40        50        60
pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_003 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDA
              130       140       150       160       170       180

              
pF1KE0 AKSPTSQ
       :::::::
NP_003 AKSPTSQ
              

>>NP_000354 (OMIM: 115210,191044,611880,613286,613690) t  (210 aa)
 initn: 708 init1: 584 opt: 706  Z-score: 720.7  bits: 140.2 E(85289): 2.1e-33
Smith-Waterman score: 706; 62.6% identity (82.1% similar) in 179 aa overlap (2-180:33-210)

                                            10        20        30 
pF1KE0                              MPEVERKPKITASRKLLLKSLMLAKAKECWE
                                     :....: ::.::::: ::.:.:  ::.  :
NP_000 DGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELE
             10        20        30        40        50        60  

              40        50        60        70        80        90 
pF1KE0 QEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNT
       .: :::..:: : :. :   :.  ::... ::::::.:::.:. :::::::::::  .: 
NP_000 REAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNI
             70        80        90       100       110       120  

             100       110       120       130       140       150 
pF1KE0 REIKDLKLKVMALRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTE
        :: ::  :.. :::::::: :::::.:::::..::::.. : :.::::.::.:::::::
NP_000 TEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTE
            130       140       150       160       170       180  

             160       170       180       
pF1KE0 KERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ
       ::   ::::::::..:.:::::::: :..       
NP_000 KENR-EVGDWRKNIDALSGMEGRKKKFES       
             190       200       210       

>>NP_003273 (OMIM: 191043,601680) troponin I, fast skele  (182 aa)
 initn: 570 init1: 448 opt: 684  Z-score: 699.6  bits: 136.1 E(85289): 3.1e-32
Smith-Waterman score: 684; 58.0% identity (82.9% similar) in 181 aa overlap (1-180:1-180)

               10        20        30        40        50        60
pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
       : . :.. .  ..:.  :::.::  :    :.:. .:::::  ::::. : :.  : :.:
NP_003 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA
        .:.::..::::.....::.::.:..  ....:..:.. :.. ::::::::::::::.::
NP_003 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA
      60        70        80        90       100       110         

              130       140       150        160       170         
pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD
       ::::.::::::::: ::::::::.:::::::::: . .:::::::.:  ::::::::::.
NP_003 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE
     120       130       140       150       160       170         

     180       
pF1KE0 AAKSPTSQ
       .       
NP_003 SES     
     180       

>>NP_001139301 (OMIM: 191043,601680) troponin I, fast sk  (182 aa)
 initn: 570 init1: 448 opt: 684  Z-score: 699.6  bits: 136.1 E(85289): 3.1e-32
Smith-Waterman score: 684; 58.0% identity (82.9% similar) in 181 aa overlap (1-180:1-180)

               10        20        30        40        50        60
pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
       : . :.. .  ..:.  :::.::  :    :.:. .:::::  ::::. : :.  : :.:
NP_001 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA
        .:.::..::::.....::.::.:..  ....:..:.. :.. ::::::::::::::.::
NP_001 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA
      60        70        80        90       100       110         

              130       140       150        160       170         
pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD
       ::::.::::::::: ::::::::.:::::::::: . .:::::::.:  ::::::::::.
NP_001 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE
     120       130       140       150       160       170         

     180       
pF1KE0 AAKSPTSQ
       .       
NP_001 SES     
     180       

>>NP_001139313 (OMIM: 191043,601680) troponin I, fast sk  (182 aa)
 initn: 570 init1: 448 opt: 682  Z-score: 697.7  bits: 135.7 E(85289): 4e-32
Smith-Waterman score: 682; 57.5% identity (82.9% similar) in 181 aa overlap (1-180:1-180)

               10        20        30        40        50        60
pF1KE0 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
       : . ... .  ..:.  :::.::  :    :.:. .:::::  ::::. : :.  : :.:
NP_001 MSQCKKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KE0 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMALRGKFKRPPLRRVRVSA
        .:.::..::::.....::.::.:..  ....:..:.. :.. ::::::::::::::.::
NP_001 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA
      60        70        80        90       100       110         

              130       140       150        160       170         
pF1KE0 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD
       ::::.::::::::: ::::::::.:::::::::: . .:::::::.:  ::::::::::.
NP_001 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE
     120       130       140       150       160       170         

     180       
pF1KE0 AAKSPTSQ
       .       
NP_001 SES     
     180       




187 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:12:11 2016 done: Thu Nov  3 23:12:12 2016
 Total Scan time:  5.360 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]