FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0167, 164 aa 1>>>pF1KE0167 164 - 164 aa - 164 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5906+/-0.000261; mu= 16.7585+/- 0.016 mean_var=63.6676+/-12.704, 0's: 0 Z-trim(120.1): 23 B-trim: 0 in 0/58 Lambda= 0.160737 statistics sampled from 34930 (34954) to 34930 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.41), width: 16 Scan time: 5.460 The best scores are: opt bits E(85289) NP_060629 (OMIM: 300528) diphosphoinositol polypho ( 164) 1129 269.3 1.9e-72 NP_001291892 (OMIM: 300527) diphosphoinositol poly ( 164) 1119 267.0 9.6e-72 NP_694853 (OMIM: 300527) diphosphoinositol polypho ( 164) 1119 267.0 9.6e-72 NP_950241 (OMIM: 609229) diphosphoinositol polypho ( 181) 1024 245.0 4.4e-65 NP_061967 (OMIM: 609229) diphosphoinositol polypho ( 180) 1005 240.6 9.3e-64 NP_006694 (OMIM: 609228) diphosphoinositol polypho ( 172) 818 197.2 1e-50 XP_011536096 (OMIM: 609229) PREDICTED: diphosphoin ( 129) 696 168.8 2.7e-42 NP_001287951 (OMIM: 609229) diphosphoinositol poly ( 129) 696 168.8 2.7e-42 NP_001287953 (OMIM: 609229) diphosphoinositol poly ( 128) 677 164.4 5.7e-41 XP_011536097 (OMIM: 609229) PREDICTED: diphosphoin ( 128) 677 164.4 5.7e-41 XP_011536098 (OMIM: 609229) PREDICTED: diphosphoin ( 128) 677 164.4 5.7e-41 NP_001287952 (OMIM: 609229) diphosphoinositol poly ( 128) 677 164.4 5.7e-41 NP_009014 (OMIM: 606261) nucleoside diphosphate-li ( 316) 151 42.8 0.00058 NP_932158 (OMIM: 606261) nucleoside diphosphate-li ( 147) 143 40.6 0.0012 NP_001229306 (OMIM: 609844) m7GpppN-mRNA hydrolase ( 385) 136 39.4 0.0075 XP_016864652 (OMIM: 609844) PREDICTED: m7GpppN-mRN ( 405) 136 39.4 0.0078 NP_689837 (OMIM: 609844) m7GpppN-mRNA hydrolase is ( 420) 136 39.4 0.008 >>NP_060629 (OMIM: 300528) diphosphoinositol polyphospha (164 aa) initn: 1129 init1: 1129 opt: 1129 Z-score: 1421.5 bits: 269.3 E(85289): 1.9e-72 Smith-Waterman score: 1129; 100.0% identity (100.0% similar) in 164 aa overlap (1-164:1-164) 10 20 30 40 50 60 pF1KE0 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 AAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWF 70 80 90 100 110 120 130 140 150 160 pF1KE0 KVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP :::::::::::::::::::::::::::::::::::::::::::: NP_060 KVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP 130 140 150 160 >>NP_001291892 (OMIM: 300527) diphosphoinositol polyphos (164 aa) initn: 1119 init1: 1119 opt: 1119 Z-score: 1409.0 bits: 267.0 E(85289): 9.6e-72 Smith-Waterman score: 1119; 99.4% identity (99.4% similar) in 164 aa overlap (1-164:1-164) 10 20 30 40 50 60 pF1KE0 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWF :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: NP_001 AAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWF 70 80 90 100 110 120 130 140 150 160 pF1KE0 KVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP :::::::::::::::::::::::::::::::::::::::::::: NP_001 KVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP 130 140 150 160 >>NP_694853 (OMIM: 300527) diphosphoinositol polyphospha (164 aa) initn: 1119 init1: 1119 opt: 1119 Z-score: 1409.0 bits: 267.0 E(85289): 9.6e-72 Smith-Waterman score: 1119; 99.4% identity (99.4% similar) in 164 aa overlap (1-164:1-164) 10 20 30 40 50 60 pF1KE0 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWF :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: NP_694 AAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWF 70 80 90 100 110 120 130 140 150 160 pF1KE0 KVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP :::::::::::::::::::::::::::::::::::::::::::: NP_694 KVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP 130 140 150 160 >>NP_950241 (OMIM: 609229) diphosphoinositol polyphospha (181 aa) initn: 1058 init1: 1024 opt: 1024 Z-score: 1289.4 bits: 245.0 E(85289): 4.4e-65 Smith-Waterman score: 1024; 91.4% identity (96.9% similar) in 163 aa overlap (1-163:2-164) 10 20 30 40 50 pF1KE0 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPG :: ::::::::: :::::::::::::::.::::::::::::::.::::::::::::::: NP_950 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 GAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREW ::::::::::::::::::::::.::::::::::::::::::::.::::::::.::::::: NP_950 GAAVREVYEEAGVKGKLGRLLGIFEQNQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW 70 80 90 100 110 120 120 130 140 150 160 pF1KE0 FKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP ::::::::::::::::::::::::::: ::.:::: .:: ::.. NP_950 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV 130 140 150 160 170 180 NP_950 R >>NP_061967 (OMIM: 609229) diphosphoinositol polyphospha (180 aa) initn: 1023 init1: 543 opt: 1005 Z-score: 1265.6 bits: 240.6 E(85289): 9.3e-64 Smith-Waterman score: 1005; 90.8% identity (96.3% similar) in 163 aa overlap (1-163:2-163) 10 20 30 40 50 pF1KE0 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPG :: ::::::::: :::::::::::::::.::::::::::::::.::::::::::::::: NP_061 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 GAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREW ::::::::::::::::::::::.:: :::::::::::::::::.::::::::.::::::: NP_061 GAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW 70 80 90 100 110 120 130 140 150 160 pF1KE0 FKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP ::::::::::::::::::::::::::: ::.:::: .:: ::.. NP_061 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV 120 130 140 150 160 170 NP_061 R 180 >>NP_006694 (OMIM: 609228) diphosphoinositol polyphospha (172 aa) initn: 821 init1: 477 opt: 818 Z-score: 1031.5 bits: 197.2 E(85289): 1e-50 Smith-Waterman score: 818; 76.7% identity (89.3% similar) in 159 aa overlap (1-159:2-159) 10 20 30 40 50 pF1KE0 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPG :: : ::::::: .:.:::::::::::: :.:::::::::.:::::::::::::::::. NP_006 MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 GAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREW :::::: ::::::: ::::.:.:: ::.:::::::::: :::.::::::::.::::::: NP_006 VAAVREVCEEAGVKGTLGRLVGIFE-NQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREW 70 80 90 100 110 120 130 140 150 160 pF1KE0 FKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP ::.:::::::: ::::.: :.: :. : : .::. .. .. NP_006 FKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMSGIR 120 130 140 150 160 170 >>XP_011536096 (OMIM: 609229) PREDICTED: diphosphoinosit (129 aa) initn: 708 init1: 696 opt: 696 Z-score: 880.3 bits: 168.8 E(85289): 2.7e-42 Smith-Waterman score: 696; 91.1% identity (97.3% similar) in 112 aa overlap (52-163:1-112) 30 40 50 60 70 80 pF1KE0 CLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG :::::::::::::::::::::::::::::: XP_011 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG 10 20 30 90 100 110 120 130 140 pF1KE0 VFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLE .::::::::::::::::::::.::::::::.::::::::::::::::::::::::::::: XP_011 IFEQNQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLE 40 50 60 70 80 90 150 160 pF1KE0 KLKLGGSPTNGNSMAPSSPDSDP ::::: ::.:::: .:: ::.. XP_011 KLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR 100 110 120 >>NP_001287951 (OMIM: 609229) diphosphoinositol polyphos (129 aa) initn: 708 init1: 696 opt: 696 Z-score: 880.3 bits: 168.8 E(85289): 2.7e-42 Smith-Waterman score: 696; 91.1% identity (97.3% similar) in 112 aa overlap (52-163:1-112) 30 40 50 60 70 80 pF1KE0 CLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG :::::::::::::::::::::::::::::: NP_001 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG 10 20 30 90 100 110 120 130 140 pF1KE0 VFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLE .::::::::::::::::::::.::::::::.::::::::::::::::::::::::::::: NP_001 IFEQNQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLE 40 50 60 70 80 90 150 160 pF1KE0 KLKLGGSPTNGNSMAPSSPDSDP ::::: ::.:::: .:: ::.. NP_001 KLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR 100 110 120 >>NP_001287953 (OMIM: 609229) diphosphoinositol polyphos (128 aa) initn: 688 init1: 475 opt: 677 Z-score: 856.5 bits: 164.4 E(85289): 5.7e-41 Smith-Waterman score: 677; 90.2% identity (96.4% similar) in 112 aa overlap (52-163:1-111) 30 40 50 60 70 80 pF1KE0 CLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG :::::::::::::::::::::::::::::: NP_001 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG 10 20 30 90 100 110 120 130 140 pF1KE0 VFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLE .:: :::::::::::::::::.::::::::.::::::::::::::::::::::::::::: NP_001 IFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLE 40 50 60 70 80 150 160 pF1KE0 KLKLGGSPTNGNSMAPSSPDSDP ::::: ::.:::: .:: ::.. NP_001 KLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR 90 100 110 120 >>XP_011536097 (OMIM: 609229) PREDICTED: diphosphoinosit (128 aa) initn: 688 init1: 475 opt: 677 Z-score: 856.5 bits: 164.4 E(85289): 5.7e-41 Smith-Waterman score: 677; 90.2% identity (96.4% similar) in 112 aa overlap (52-163:1-111) 30 40 50 60 70 80 pF1KE0 CLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG :::::::::::::::::::::::::::::: XP_011 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG 10 20 30 90 100 110 120 130 140 pF1KE0 VFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLE .:: :::::::::::::::::.::::::::.::::::::::::::::::::::::::::: XP_011 IFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLE 40 50 60 70 80 150 160 pF1KE0 KLKLGGSPTNGNSMAPSSPDSDP ::::: ::.:::: .:: ::.. XP_011 KLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR 90 100 110 120 164 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:04:49 2016 done: Thu Nov 3 23:04:50 2016 Total Scan time: 5.460 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]