FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0169, 193 aa 1>>>pF1KE0169 193 - 193 aa - 193 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6415+/- 0.001; mu= 12.0216+/- 0.060 mean_var=96.7683+/-19.271, 0's: 0 Z-trim(106.7): 98 B-trim: 7 in 1/51 Lambda= 0.130379 statistics sampled from 9059 (9160) to 9059 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.281), width: 16 Scan time: 1.950 The best scores are: opt bits E(32554) CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 ( 193) 1288 252.3 1.4e-67 CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 ( 193) 1199 235.5 1.5e-62 CCDS370.1 HPCA gene_id:3208|Hs108|chr1 ( 193) 1151 226.5 7.9e-60 CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 ( 191) 924 183.8 5.6e-47 CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 ( 191) 888 177.0 6.1e-45 CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 ( 190) 794 159.3 1.3e-39 CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 ( 172) 707 142.9 1e-34 CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 ( 200) 675 137.0 7.3e-33 CCDS7524.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 220) 550 113.5 9.4e-26 CCDS7525.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 225) 550 113.5 9.5e-26 CCDS41562.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 252) 550 113.6 1e-25 CCDS7522.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 270) 550 113.6 1.1e-25 CCDS7521.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 285) 550 113.6 1.1e-25 CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 188) 547 112.9 1.2e-25 CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 216) 547 112.9 1.4e-25 CCDS34285.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 225) 547 112.9 1.4e-25 CCDS34286.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 227) 547 113.0 1.4e-25 CCDS47035.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 188) 533 110.2 7.7e-25 CCDS43215.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 216) 533 110.3 8.5e-25 CCDS43217.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 225) 533 110.3 8.8e-25 CCDS3428.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 229) 533 110.3 8.9e-25 CCDS43216.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 250) 533 110.4 9.5e-25 CCDS7523.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 227) 532 110.1 1e-24 CCDS33245.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 230) 530 109.8 1.3e-24 CCDS2013.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 256) 530 109.8 1.4e-24 CCDS4865.1 GUCA1B gene_id:2979|Hs108|chr6 ( 200) 514 106.7 9.6e-24 CCDS4864.1 GUCA1A gene_id:2978|Hs108|chr6 ( 201) 478 99.9 1e-21 CCDS2954.1 GUCA1C gene_id:9626|Hs108|chr3 ( 209) 392 83.8 8e-17 CCDS64312.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 241) 374 80.4 9.3e-16 >>CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 (193 aa) initn: 1288 init1: 1288 opt: 1288 Z-score: 1326.8 bits: 252.3 E(32554): 1.4e-67 Smith-Waterman score: 1288; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPSIV :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: CCDS62 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 130 140 150 160 170 180 190 pF1KE0 RLLQCDPSSAGQF ::::::::::::: CCDS62 RLLQCDPSSAGQF 190 >>CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 (193 aa) initn: 1199 init1: 1199 opt: 1199 Z-score: 1236.3 bits: 235.5 E(32554): 1.5e-62 Smith-Waterman score: 1199; 90.2% identity (99.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD ::::::::::::.::: :.:.::.::.::::::::.:::.:::...::::::.::::::: CCDS16 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::..: CCDS16 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPSIV :::::::::::::::::::::::::::::.::::::::: :::::.:::::::::::::: CCDS16 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 130 140 150 160 170 180 190 pF1KE0 RLLQCDPSSAGQF ::::::::::.:: CCDS16 RLLQCDPSSASQF 190 >>CCDS370.1 HPCA gene_id:3208|Hs108|chr1 (193 aa) initn: 1151 init1: 1151 opt: 1151 Z-score: 1187.5 bits: 226.5 E(32554): 7.9e-60 Smith-Waterman score: 1151; 87.6% identity (96.9% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD :::::::::::..::: :.:.:.: :.::::::::.:::.: :...::::::.::::::: CCDS37 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE :::::::::::::.:.:::::::::::::::::::.::::: :::::::::::::::. : CCDS37 ASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPSIV ::::::::::::::::::::::::::::::::::::::: :::::.:::::::::::::: CCDS37 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 130 140 150 160 170 180 190 pF1KE0 RLLQCDPSSAGQF ::::::::::.:: CCDS37 RLLQCDPSSASQF 190 >>CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 (191 aa) initn: 735 init1: 735 opt: 924 Z-score: 956.8 bits: 183.8 E(32554): 5.6e-47 Smith-Waterman score: 924; 69.1% identity (92.0% similar) in 188 aa overlap (1-186:1-188) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD :::::::: ::::.::..::.:.:::...::::::.:::::.:..:::...: .:::::: CCDS16 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE :::::.:.::::: :::::::::::: :::.::::..::::.:::.::::::.: :...: CCDS16 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPS ::::..::::::..: ::: :: :::.:..::: .:: :.: .....:: ..:::::: CCDS16 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS 130 140 150 160 170 180 180 190 pF1KE0 IVRLLQCDPSSAGQF :: ::::: CCDS16 IVLLLQCDIQK 190 >>CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 (191 aa) initn: 702 init1: 702 opt: 888 Z-score: 920.3 bits: 177.0 E(32554): 6.1e-45 Smith-Waterman score: 888; 66.0% identity (90.4% similar) in 188 aa overlap (1-186:1-188) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD ::: :::: :::..::...:.:.:.:...::::::.::::: :..:::...: .:::::: CCDS44 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE :::::.:.::::: :::::::::::: ::::::::..::::.::: ::::::.: :.. : CCDS44 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPS ::::..::::::..: :.: .: ::..:..:::..:: ..: ....::: ..:::::: CCDS44 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS 130 140 150 160 170 180 180 190 pF1KE0 IVRLLQCDPSSAGQF :: ::::: CCDS44 IVLLLQCDMQK 190 >>CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 (190 aa) initn: 840 init1: 794 opt: 794 Z-score: 824.7 bits: 159.3 E(32554): 1.3e-39 Smith-Waterman score: 794; 60.1% identity (88.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD :::.::::.:::...: ..: :::.:.:.:::::..:::::.:. :.::: .:::.:: CCDS69 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE .::: :: .:: : :: :.: ::: :::::::: :..::.:::..::::..:::.. : CCDS69 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPSIV ::.::.:::.::......::.:.:::::...:: .:: : ::::...:: .:.:.::::: CCDS69 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 130 140 150 160 170 180 190 pF1KE0 RLLQCDPSSAGQF . : CCDS69 QALSLYDGLV 190 >>CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 (172 aa) initn: 753 init1: 707 opt: 707 Z-score: 736.9 bits: 142.9 E(32554): 1e-34 Smith-Waterman score: 707; 60.2% identity (87.6% similar) in 161 aa overlap (23-183:5-165) 10 20 30 40 50 60 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD ::.:.:.:::::..:::::.:. :.::: .:::.:: CCDS78 MATITEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 70 80 90 100 110 120 pF1KE0 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE .::: :: .:: : :: :.: ::: :::::::: :..::.:::..::::..:::.. : CCDS78 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDPSIV ::.::.:::.::......::.:.:::::...:: .:: : ::::...:: .:.:.::::: CCDS78 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 110 120 130 140 150 160 190 pF1KE0 RLLQCDPSSAGQF . : CCDS78 QALSLYDGLV 170 >>CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 (200 aa) initn: 608 init1: 469 opt: 675 Z-score: 703.5 bits: 137.0 E(32554): 7.3e-33 Smith-Waterman score: 675; 50.0% identity (82.6% similar) in 190 aa overlap (1-187:1-190) 10 20 30 40 50 pF1KE0 MGKQNS-KLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYG ::...: : :....: .: :.:.:. ::..::.:::.:......:..::..::: CCDS11 MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 DASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKA : . .:.::::.::.: :::.::.:..::: .:. :: .:::.::::.::.:::: ::: CCDS11 DPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 EMLEIVQAIYKMVS--SVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSMEEFIRGAKSDP :.::::.::.::.. .: .:.::.:::::.:::.. . : : ::. .:::.:. .. CCDS11 EVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK 130 140 150 160 170 180 180 190 pF1KE0 SIVRLLQCDPSSAGQF :.::.: .: CCDS11 EILRLIQFEPQKVKEKMKNA 190 200 >>CCDS7524.1 KCNIP2 gene_id:30819|Hs108|chr10 (220 aa) initn: 620 init1: 550 opt: 550 Z-score: 575.8 bits: 113.5 E(32554): 9.4e-26 Smith-Waterman score: 550; 43.2% identity (79.5% similar) in 176 aa overlap (9-184:39-214) 10 20 30 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDC ::: ...: :.: ::..:.: :.:: .: CCDS75 SLSDSRDLDGSYDQLTDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNEC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE0 PSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLE ::: .. :.::.::..::: ::.: .: .: .::.: ::...:..:. .::: :: .. CCDS75 PSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVD 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE0 QKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT ..:.:::..:::. .: :.: :::.:...:: :... : .:....:..:..:: CCDS75 DRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDR 130 140 150 160 170 180 160 170 180 190 pF1KE0 NRDGKLSMEEFIRGAKSDPSIVRLLQCDPSSAGQF :.:: ...::::.. ..: .:.: .: CCDS75 NKDGVVTIEEFIESCQKDENIMRSMQLFDNVI 190 200 210 220 >>CCDS7525.1 KCNIP2 gene_id:30819|Hs108|chr10 (225 aa) initn: 604 init1: 550 opt: 550 Z-score: 575.7 bits: 113.5 E(32554): 9.5e-26 Smith-Waterman score: 550; 43.2% identity (79.5% similar) in 176 aa overlap (9-184:44-219) 10 20 30 pF1KE0 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDC ::: ...: :.: ::..:.: :.:: .: CCDS75 QAARSLYQLVTGSLSPDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNEC 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE0 PSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLE ::: .. :.::.::..::: ::.: .: .: .::.: ::...:..:. .::: :: .. CCDS75 PSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE0 QKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT ..:.:::..:::. .: :.: :::.:...:: :... : .:....:..:..:: CCDS75 DRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDR 140 150 160 170 180 190 160 170 180 190 pF1KE0 NRDGKLSMEEFIRGAKSDPSIVRLLQCDPSSAGQF :.:: ...::::.. ..: .:.: .: CCDS75 NKDGVVTIEEFIESCQKDENIMRSMQLFDNVI 200 210 220 193 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:59:28 2016 done: Thu Nov 3 22:59:28 2016 Total Scan time: 1.950 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]