FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0171, 222 aa 1>>>pF1KE0171 222 - 222 aa - 222 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2354+/-0.000333; mu= 13.8991+/- 0.021 mean_var=61.6050+/-12.265, 0's: 0 Z-trim(115.0): 16 B-trim: 55 in 1/50 Lambda= 0.163405 statistics sampled from 25155 (25167) to 25155 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.295), width: 16 Scan time: 5.500 The best scores are: opt bits E(85289) NP_000627 (OMIM: 147460,612634) superoxide dismuta ( 222) 1536 370.3 1.4e-102 NP_001019636 (OMIM: 147460,612634) superoxide dism ( 222) 1536 370.3 1.4e-102 NP_001309746 (OMIM: 147460,612634) superoxide dism ( 176) 1223 296.5 1.8e-80 NP_001309749 (OMIM: 147460,612634) superoxide dism ( 176) 1223 296.5 1.8e-80 NP_001309748 (OMIM: 147460,612634) superoxide dism ( 176) 1223 296.5 1.8e-80 NP_001309744 (OMIM: 147460,612634) superoxide dism ( 162) 785 193.2 2.1e-49 NP_001019637 (OMIM: 147460,612634) superoxide dism ( 183) 765 188.5 6.1e-48 NP_001309743 (OMIM: 147460,612634) superoxide dism ( 183) 765 188.5 6.1e-48 NP_001309745 (OMIM: 147460,612634) superoxide dism ( 140) 513 129.1 3.7e-30 >>NP_000627 (OMIM: 147460,612634) superoxide dismutase [ (222 aa) initn: 1536 init1: 1536 opt: 1536 Z-score: 1962.7 bits: 370.3 E(85289): 1.4e-102 Smith-Waterman score: 1536; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KE0 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL 130 140 150 160 170 180 190 200 210 220 pF1KE0 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::::::::::::::::::: NP_000 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK 190 200 210 220 >>NP_001019636 (OMIM: 147460,612634) superoxide dismutas (222 aa) initn: 1536 init1: 1536 opt: 1536 Z-score: 1962.7 bits: 370.3 E(85289): 1.4e-102 Smith-Waterman score: 1536; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KE0 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL 130 140 150 160 170 180 190 200 210 220 pF1KE0 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::::::::::::::::::: NP_001 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK 190 200 210 220 >>NP_001309746 (OMIM: 147460,612634) superoxide dismutas (176 aa) initn: 1223 init1: 1223 opt: 1223 Z-score: 1565.5 bits: 296.5 E(85289): 1.8e-80 Smith-Waterman score: 1223; 100.0% identity (100.0% similar) in 176 aa overlap (47-222:1-176) 20 30 40 50 60 70 pF1KE0 LGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKG :::::::::::::::::::::::::::::: NP_001 MQLHHSKHHAAYVNNLNVTEEKYQEALAKG 10 20 30 80 90 100 110 120 130 pF1KE0 DVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLT 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 AASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNV 100 110 120 130 140 150 200 210 220 pF1KE0 RPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::: NP_001 RPDYLKAIWNVINWENVTERYMACKK 160 170 >>NP_001309749 (OMIM: 147460,612634) superoxide dismutas (176 aa) initn: 1223 init1: 1223 opt: 1223 Z-score: 1565.5 bits: 296.5 E(85289): 1.8e-80 Smith-Waterman score: 1223; 100.0% identity (100.0% similar) in 176 aa overlap (47-222:1-176) 20 30 40 50 60 70 pF1KE0 LGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKG :::::::::::::::::::::::::::::: NP_001 MQLHHSKHHAAYVNNLNVTEEKYQEALAKG 10 20 30 80 90 100 110 120 130 pF1KE0 DVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLT 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 AASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNV 100 110 120 130 140 150 200 210 220 pF1KE0 RPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::: NP_001 RPDYLKAIWNVINWENVTERYMACKK 160 170 >>NP_001309748 (OMIM: 147460,612634) superoxide dismutas (176 aa) initn: 1223 init1: 1223 opt: 1223 Z-score: 1565.5 bits: 296.5 E(85289): 1.8e-80 Smith-Waterman score: 1223; 100.0% identity (100.0% similar) in 176 aa overlap (47-222:1-176) 20 30 40 50 60 70 pF1KE0 LGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKG :::::::::::::::::::::::::::::: NP_001 MQLHHSKHHAAYVNNLNVTEEKYQEALAKG 10 20 30 80 90 100 110 120 130 pF1KE0 DVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLT 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 AASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNV 100 110 120 130 140 150 200 210 220 pF1KE0 RPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::: NP_001 RPDYLKAIWNVINWENVTERYMACKK 160 170 >>NP_001309744 (OMIM: 147460,612634) superoxide dismutas (162 aa) initn: 785 init1: 785 opt: 785 Z-score: 1008.0 bits: 193.2 E(85289): 2.1e-49 Smith-Waterman score: 990; 73.0% identity (73.0% similar) in 222 aa overlap (1-222:1-162) 10 20 30 40 50 60 pF1KE0 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKG----- 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL ::::: NP_001 -------------------------------------------------------LIPLL 120 190 200 210 220 pF1KE0 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::::::::::::::::::: NP_001 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK 130 140 150 160 >>NP_001019637 (OMIM: 147460,612634) superoxide dismutas (183 aa) initn: 765 init1: 765 opt: 765 Z-score: 981.7 bits: 188.5 E(85289): 6.1e-48 Smith-Waterman score: 1173; 82.4% identity (82.4% similar) in 222 aa overlap (1-222:1-183) 10 20 30 40 50 60 pF1KE0 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA :::::::::::::::: ::::: NP_001 NLNVTEEKYQEALAKG---------------------------------------ELLEA 70 80 130 140 150 160 170 180 pF1KE0 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL 90 100 110 120 130 140 190 200 210 220 pF1KE0 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::::::::::::::::::: NP_001 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK 150 160 170 180 >>NP_001309743 (OMIM: 147460,612634) superoxide dismutas (183 aa) initn: 765 init1: 765 opt: 765 Z-score: 981.7 bits: 188.5 E(85289): 6.1e-48 Smith-Waterman score: 1173; 82.4% identity (82.4% similar) in 222 aa overlap (1-222:1-183) 10 20 30 40 50 60 pF1KE0 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA :::::::::::::::: ::::: NP_001 NLNVTEEKYQEALAKG---------------------------------------ELLEA 70 80 130 140 150 160 170 180 pF1KE0 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL 90 100 110 120 130 140 190 200 210 220 pF1KE0 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK :::::::::::::::::::::::::::::::::::::::::: NP_001 GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK 150 160 170 180 >>NP_001309745 (OMIM: 147460,612634) superoxide dismutas (140 aa) initn: 513 init1: 513 opt: 513 Z-score: 662.4 bits: 129.1 E(85289): 3.7e-30 Smith-Waterman score: 513; 95.1% identity (96.3% similar) in 81 aa overlap (1-81:1-81) 10 20 30 40 50 60 pF1KE0 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA :::::::::::::::: :. NP_001 NLNVTEEKYQEALAKGRFQAERREAVPGRGDPREPGPIRTGLSVEENSLRICTGSEFSRH 70 80 90 100 110 120 222 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:00:00 2016 done: Thu Nov 3 23:00:02 2016 Total Scan time: 5.500 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]