FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0172, 317 aa 1>>>pF1KE0172 317 - 317 aa - 317 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1602+/-0.000819; mu= 16.6148+/- 0.049 mean_var=63.9572+/-12.911, 0's: 0 Z-trim(106.8): 19 B-trim: 536 in 1/50 Lambda= 0.160372 statistics sampled from 9179 (9189) to 9179 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.282), width: 16 Scan time: 2.160 The best scores are: opt bits E(32554) CCDS7416.1 PPP1R3C gene_id:5507|Hs108|chr10 ( 317) 2202 518.0 3.7e-147 CCDS5973.1 PPP1R3B gene_id:79660|Hs108|chr8 ( 285) 773 187.4 1.2e-47 CCDS13483.1 PPP1R3D gene_id:5509|Hs108|chr20 ( 299) 340 87.2 1.7e-17 CCDS5759.1 PPP1R3A gene_id:5506|Hs108|chr7 (1122) 337 86.8 8.4e-17 >>CCDS7416.1 PPP1R3C gene_id:5507|Hs108|chr10 (317 aa) initn: 2202 init1: 2202 opt: 2202 Z-score: 2755.3 bits: 518.0 E(32554): 3.7e-147 Smith-Waterman score: 2202; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL 250 260 270 280 290 300 310 pF1KE0 FPEWQSWGRMENLASYR ::::::::::::::::: CCDS74 FPEWQSWGRMENLASYR 310 >>CCDS5973.1 PPP1R3B gene_id:79660|Hs108|chr8 (285 aa) initn: 689 init1: 529 opt: 773 Z-score: 969.2 bits: 187.4 E(32554): 1.2e-47 Smith-Waterman score: 773; 40.5% identity (71.8% similar) in 301 aa overlap (19-316:1-284) 10 20 30 40 50 pF1KE0 MSCTRMIQVLDPRPLTSSVMPVDVAMRL-CLAHSPPVKSFLGPYDEFQRRHFVNKLKPLK .: ::. .: :.: : ... ..: . . :::. CCDS59 MMAVDIEYRYNCMA--PSLRQ-----ERFAFKISPKPSKPLR 10 20 30 60 70 80 90 100 110 pF1KE0 SCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLL :... :..:... .....:::: :::..::.:: ..:::.. ..: :. :.. CCDS59 PCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMPFNIT 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 DLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKN .: : .: : ....::: :::.:::.::...: . :::::: :......:::::.: CCDS59 ELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQN 100 110 120 130 140 150 180 190 200 210 220 230 pF1KE0 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCIS ..::: :.::.:::.::.::: : :.:..:.:.: ::::: :.:: : . ...:: . CCDS59 LAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVY 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE0 YHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLA :. :::..::.: :.::::.... : ..: . : ...: . ::::: . CCDS59 YECNGQTYWDSNRGKNYRIIRAELK--STQGMTKP------HSGPDLGISFDQFGSPRCS 220 230 240 250 260 300 310 pF1KE0 SGLFPEWQSWGRMENLASYR :::::: :. .:.:. : CCDS59 YGLFPEWPSYLGYEKLGPYY 270 280 >>CCDS13483.1 PPP1R3D gene_id:5509|Hs108|chr20 (299 aa) initn: 270 init1: 155 opt: 340 Z-score: 427.4 bits: 87.2 E(32554): 1.7e-17 Smith-Waterman score: 344; 29.5% identity (58.5% similar) in 275 aa overlap (10-265:19-289) 10 20 30 40 pF1KE0 MSCTRMIQVLDPRPLTS-SVMPVDVAM--RLCL-----AHSPPVKSFLGPY : :: :. : . ::. : : ...:: . CCDS13 MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 DEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKK-RVVFADSKGLSLTAIHVFS : : .. . . : : . ..:: . : . ..: :: :::. :: :. ..:: CCDS13 DPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVF- 70 80 90 100 110 110 120 130 140 150 pF1KE0 DLPEEPAWDLQ-FDLLDLN-DISSALKHHEE--KNLILDFPQPSTDYLSFRSHFQKNFVC . ..:. :. .. : .: :. . . : . :. ::: : .. .: ..:...:: CCDS13 NAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPP-VEAADFGERLQRQLVC 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 LENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYG--GTDSDTF :: . .. ..:::.: ::.:::.: .: ::..:.. : . .. : ::. :.: CCDS13 LERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRS-THEAVARWRGPAGPEGTE-DVF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 SFAIDLPP-VIPTEQKIEFCISYHANGQVFWDNNDGQNYRIV---HVQWKPDGVQTQMAP .:.. .:: .. ....: . :.. : .::::: ..: .. :. : : CCDS13 TFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWI 240 250 260 270 280 290 280 290 300 310 pF1KE0 QDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR CCDS13 HFI >>CCDS5759.1 PPP1R3A gene_id:5506|Hs108|chr7 (1122 aa) initn: 272 init1: 229 opt: 337 Z-score: 415.2 bits: 86.8 E(32554): 8.4e-17 Smith-Waterman score: 337; 33.7% identity (63.2% similar) in 190 aa overlap (83-267:62-242) 60 70 80 90 100 110 pF1KE0 NKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDL .:: :::: :..:.... : : : :. . CCDS57 TFQPGFSPQPSRRGSDSSEDIYLDTPSSGTRRVSFADSFGFNLVSVKEF-DCWELPSAST 40 50 60 70 80 90 120 130 140 150 160 170 pF1KE0 QFDLLDLNDISSALKHHEEKNL--ILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVT ::: .. . : :: : ..:.:. . : .. . ..:: .. . : .. CCDS57 TFDL------GTDIFHTEEYVLAPLFDLPSSKEDLMQ-QLQIQKAILESTESLLGSTSIK 100 110 120 130 140 180 190 200 210 220 pF1KE0 GTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDL-PPVIPTE : ..: :::::: : .:...:.:... :. :. : : ..: ::: : : :: CCDS57 GIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNSCDG-ETDQFSFKIVLVPPYQKDG 150 160 170 180 190 200 230 240 250 260 270 280 pF1KE0 QKIEFCISYHANGQVFWDNNDGQNYRIV--HVQWKPDGVQTQMAPQDCAFHQTSPKTELE .:.:::: :... .::.::.: :: .. . . .:. :. CCDS57 SKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEPVKPWKEVPNRQIKGCLKVKSSK 210 220 230 240 250 260 290 300 310 pF1KE0 STIFGSPRLASGLFPEWQSWGRMENLASYR CCDS57 EESSVTSEENNFENPKNTDTYIPTIICSHEDKEDLEASNRNVKDVNREHDEHNEKELELM 270 280 290 300 310 320 317 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:55:06 2016 done: Thu Nov 3 22:55:06 2016 Total Scan time: 2.160 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]