FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0180, 218 aa 1>>>pF1KE0180 218 - 218 aa - 218 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9105+/-0.000315; mu= 16.2473+/- 0.020 mean_var=63.6913+/-13.145, 0's: 0 Z-trim(116.2): 27 B-trim: 14 in 2/55 Lambda= 0.160707 statistics sampled from 27124 (27151) to 27124 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.318), width: 16 Scan time: 6.570 The best scores are: opt bits E(85289) XP_006711995 (OMIM: 616757) PREDICTED: transmembra ( 218) 1435 340.8 1e-93 XP_011530810 (OMIM: 616757) PREDICTED: transmembra ( 218) 1435 340.8 1e-93 XP_016858796 (OMIM: 616757) PREDICTED: transmembra ( 224) 1188 283.6 1.8e-76 XP_016858794 (OMIM: 616757) PREDICTED: transmembra ( 224) 1188 283.6 1.8e-76 XP_016858795 (OMIM: 616757) PREDICTED: transmembra ( 224) 1188 283.6 1.8e-76 XP_011530809 (OMIM: 616757) PREDICTED: transmembra ( 224) 1188 283.6 1.8e-76 XP_011530807 (OMIM: 616757) PREDICTED: transmembra ( 247) 1188 283.6 1.9e-76 XP_006711993 (OMIM: 616757) PREDICTED: transmembra ( 271) 1188 283.6 2.1e-76 NP_001026908 (OMIM: 616757) transmembrane protein ( 271) 1188 283.6 2.1e-76 XP_006711994 (OMIM: 616757) PREDICTED: transmembra ( 271) 1188 283.6 2.1e-76 >>XP_006711995 (OMIM: 616757) PREDICTED: transmembrane p (218 aa) initn: 1435 init1: 1435 opt: 1435 Z-score: 1803.5 bits: 340.8 E(85289): 1e-93 Smith-Waterman score: 1435; 99.5% identity (100.0% similar) in 218 aa overlap (1-218:1-218) 10 20 30 40 50 60 pF1KE0 MYALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MYALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VAYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVS ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: XP_006 VAYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVS 130 140 150 160 170 180 190 200 210 pF1KE0 SDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI :::::::::::::::::::::::::::::::::::::: XP_006 SDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 190 200 210 >>XP_011530810 (OMIM: 616757) PREDICTED: transmembrane p (218 aa) initn: 1435 init1: 1435 opt: 1435 Z-score: 1803.5 bits: 340.8 E(85289): 1e-93 Smith-Waterman score: 1435; 99.5% identity (100.0% similar) in 218 aa overlap (1-218:1-218) 10 20 30 40 50 60 pF1KE0 MYALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VAYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVS ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: XP_011 VAYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVS 130 140 150 160 170 180 190 200 210 pF1KE0 SDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI :::::::::::::::::::::::::::::::::::::: XP_011 SDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 190 200 210 >>XP_016858796 (OMIM: 616757) PREDICTED: transmembrane p (224 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1493.9 bits: 283.6 E(85289): 1.8e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:38-224) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_016 HKSVACLLRSRCSKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 130 140 150 160 170 180 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_016 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 190 200 210 220 >>XP_016858794 (OMIM: 616757) PREDICTED: transmembrane p (224 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1493.9 bits: 283.6 E(85289): 1.8e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:38-224) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_016 HKSVACLLRSRCSKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 130 140 150 160 170 180 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_016 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 190 200 210 220 >>XP_016858795 (OMIM: 616757) PREDICTED: transmembrane p (224 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1493.9 bits: 283.6 E(85289): 1.8e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:38-224) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_016 HKSVACLLRSRCSKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 130 140 150 160 170 180 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_016 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 190 200 210 220 >>XP_011530809 (OMIM: 616757) PREDICTED: transmembrane p (224 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1493.9 bits: 283.6 E(85289): 1.8e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:38-224) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_011 HKSVACLLRSRCSKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_011 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 130 140 150 160 170 180 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_011 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 190 200 210 220 >>XP_011530807 (OMIM: 616757) PREDICTED: transmembrane p (247 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1493.3 bits: 283.6 E(85289): 1.9e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:61-247) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_011 KTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 40 50 60 70 80 90 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 100 110 120 130 140 150 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_011 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 160 170 180 190 200 210 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_011 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 220 230 240 >>XP_006711993 (OMIM: 616757) PREDICTED: transmembrane p (271 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1492.7 bits: 283.6 E(85289): 2.1e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:85-271) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_006 KTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 60 70 80 90 100 110 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 120 130 140 150 160 170 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_006 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 180 190 200 210 220 230 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_006 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 240 250 260 270 >>NP_001026908 (OMIM: 616757) transmembrane protein 150A (271 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1492.7 bits: 283.6 E(85289): 2.1e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:85-271) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: NP_001 KTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 60 70 80 90 100 110 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 120 130 140 150 160 170 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 180 190 200 210 220 230 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: NP_001 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 240 250 260 270 >>XP_006711994 (OMIM: 616757) PREDICTED: transmembrane p (271 aa) initn: 1187 init1: 1187 opt: 1188 Z-score: 1492.7 bits: 283.6 E(85289): 2.1e-76 Smith-Waterman score: 1188; 97.3% identity (98.4% similar) in 187 aa overlap (32-218:85-271) 10 20 30 40 50 60 pF1KE0 YALWRTGPTTSPALLTLLSKGVPRPAAPWTMSPSSVALICLLRYGQLLEQSRHSWVNTTA :. ::::::::::::::::::::::::: XP_006 KTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTA 60 70 80 90 100 110 70 80 90 100 110 120 pF1KE0 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAV 120 130 140 150 160 170 130 140 150 160 170 180 pF1KE0 AYLRSVLAVIAFITLVLSGVFFVHESSRLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_006 AYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSS 180 190 200 210 220 230 190 200 210 pF1KE0 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI ::::::::::::::::::::::::::::::::::::: XP_006 DTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI 240 250 260 270 218 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:27:13 2016 done: Thu Nov 3 22:27:14 2016 Total Scan time: 6.570 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]