FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0182, 226 aa 1>>>pF1KE0182 226 - 226 aa - 226 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1651+/-0.000328; mu= 14.5384+/- 0.021 mean_var=60.0186+/-11.904, 0's: 0 Z-trim(114.5): 12 B-trim: 452 in 1/53 Lambda= 0.165551 statistics sampled from 24402 (24413) to 24402 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.286), width: 16 Scan time: 6.690 The best scores are: opt bits E(85289) NP_001028676 (OMIM: 615949,615972) transmembrane p ( 226) 1427 348.9 4e-96 NP_001288675 (OMIM: 615949,615972) transmembrane p ( 226) 1427 348.9 4e-96 NP_056359 (OMIM: 615949,615972) transmembrane prot ( 226) 1427 348.9 4e-96 NP_036274 (OMIM: 607089) cyclin-D1-binding protein ( 360) 172 49.3 1e-05 XP_006720511 (OMIM: 607089) PREDICTED: cyclin-D1-b ( 404) 172 49.3 1.1e-05 >>NP_001028676 (OMIM: 615949,615972) transmembrane prote (226 aa) initn: 1427 init1: 1427 opt: 1427 Z-score: 1846.8 bits: 348.9 E(85289): 4e-96 Smith-Waterman score: 1427; 99.1% identity (99.6% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTPTEKLVAMTMGSGAKMK ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: NP_001 ELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLT 130 140 150 160 170 180 190 200 210 220 pF1KE0 GGLDWIDQSLSAAEERLEVLREAALASEPDKGLPGPEGFLQEQSAI :::::::::::::::.:::::::::::::::::::::::::::::: NP_001 GGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI 190 200 210 220 >>NP_001288675 (OMIM: 615949,615972) transmembrane prote (226 aa) initn: 1427 init1: 1427 opt: 1427 Z-score: 1846.8 bits: 348.9 E(85289): 4e-96 Smith-Waterman score: 1427; 99.1% identity (99.6% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTPTEKLVAMTMGSGAKMK ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: NP_001 ELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLT 130 140 150 160 170 180 190 200 210 220 pF1KE0 GGLDWIDQSLSAAEERLEVLREAALASEPDKGLPGPEGFLQEQSAI :::::::::::::::.:::::::::::::::::::::::::::::: NP_001 GGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI 190 200 210 220 >>NP_056359 (OMIM: 615949,615972) transmembrane protein (226 aa) initn: 1427 init1: 1427 opt: 1427 Z-score: 1846.8 bits: 348.9 E(85289): 4e-96 Smith-Waterman score: 1427; 99.1% identity (99.6% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 ELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTPTEKLVAMTMGSGAKMK ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: NP_056 ELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 TSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLT 130 140 150 160 170 180 190 200 210 220 pF1KE0 GGLDWIDQSLSAAEERLEVLREAALASEPDKGLPGPEGFLQEQSAI :::::::::::::::.:::::::::::::::::::::::::::::: NP_056 GGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI 190 200 210 220 >>NP_036274 (OMIM: 607089) cyclin-D1-binding protein 1 [ (360 aa) initn: 118 init1: 99 opt: 172 Z-score: 223.8 bits: 49.3 E(85289): 1e-05 Smith-Waterman score: 185; 27.1% identity (55.1% similar) in 207 aa overlap (17-202:149-352) 10 20 30 40 pF1KE0 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRD------LLQR : :. .. ..:.: ::: :. NP_036 RGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLT 120 130 140 150 160 170 50 60 70 80 pF1KE0 YDSKPIVDLIGAMETQSE---PSELELDDVVITNP----HIEAIL---ENED--WIEDAS . . : :: : : :.:. .: : . .: :.: : :: . NP_036 KNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQ 180 190 200 210 220 230 90 100 110 120 130 140 pF1KE0 GLMSHCIAILKICHTPTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYP :. :.:... .. .:. .. .: : .. :...::. .. .::: :::.. :.:: NP_036 ELIIPCLALVRASKACLKKIRMLVAENGKKDQV-AQLDDIVDISDEISPSVDDLALSIYP 240 250 260 270 280 290 150 160 170 180 190 200 pF1KE0 PLDPKLLDAR-TTALLLSVSHLVLVTRNACHLTGGLD--WIDQSLSAAEERLEVLREAAL :. : .: ..: :.:: . .: .: :.: . :: ..: .. .. ..: NP_036 PMCH--LTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQ 300 310 320 330 340 350 210 220 pF1KE0 ASEPDKGLPGPEGFLQEQSAI NP_036 SELEL 360 >>XP_006720511 (OMIM: 607089) PREDICTED: cyclin-D1-bindi (404 aa) initn: 139 init1: 99 opt: 172 Z-score: 223.0 bits: 49.3 E(85289): 1.1e-05 Smith-Waterman score: 185; 27.1% identity (55.1% similar) in 207 aa overlap (17-202:193-396) 10 20 30 40 pF1KE0 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRD------LLQR : :. .. ..:.: ::: :. XP_006 RGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLT 170 180 190 200 210 220 50 60 70 80 pF1KE0 YDSKPIVDLIGAMETQSE---PSELELDDVVITNP----HIEAIL---ENED--WIEDAS . . : :: : : :.:. .: : . .: :.: : :: . XP_006 KNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQ 230 240 250 260 270 280 90 100 110 120 130 140 pF1KE0 GLMSHCIAILKICHTPTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYP :. :.:... .. .:. .. .: : .. :...::. .. .::: :::.. :.:: XP_006 ELIIPCLALVRASKACLKKIRMLVAENGKKDQV-AQLDDIVDISDEISPSVDDLALSIYP 290 300 310 320 330 340 150 160 170 180 190 200 pF1KE0 PLDPKLLDAR-TTALLLSVSHLVLVTRNACHLTGGLD--WIDQSLSAAEERLEVLREAAL :. : .: ..: :.:: . .: .: :.: . :: ..: .. .. ..: XP_006 PMCH--LTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQ 350 360 370 380 390 210 220 pF1KE0 ASEPDKGLPGPEGFLQEQSAI XP_006 SELEL 400 226 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:23:00 2016 done: Thu Nov 3 22:23:01 2016 Total Scan time: 6.690 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]