FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0183, 322 aa 1>>>pF1KE0183 322 - 322 aa - 322 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2106+/-0.000873; mu= 16.0329+/- 0.052 mean_var=59.0014+/-11.819, 0's: 0 Z-trim(104.9): 17 B-trim: 2 in 1/51 Lambda= 0.166972 statistics sampled from 8102 (8114) to 8102 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.249), width: 16 Scan time: 2.270 The best scores are: opt bits E(32554) CCDS4394.1 SFXN1 gene_id:94081|Hs108|chr5 ( 322) 2137 523.2 1.1e-148 CCDS7508.2 SFXN3 gene_id:81855|Hs108|chr10 ( 325) 1729 424.9 4.2e-119 CCDS7539.1 SFXN2 gene_id:118980|Hs108|chr10 ( 322) 1192 295.5 3.7e-80 CCDS1922.1 SFXN5 gene_id:94097|Hs108|chr2 ( 340) 783 197.0 1.8e-50 CCDS82469.1 SFXN5 gene_id:94097|Hs108|chr2 ( 253) 501 129.0 3.8e-30 CCDS7610.1 SFXN4 gene_id:119559|Hs108|chr10 ( 337) 312 83.6 2.5e-16 >>CCDS4394.1 SFXN1 gene_id:94081|Hs108|chr5 (322 aa) initn: 2137 init1: 2137 opt: 2137 Z-score: 2782.9 bits: 523.2 E(32554): 1.1e-148 Smith-Waterman score: 2137; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA 250 260 270 280 290 300 310 320 pF1KE0 ELQAKIQESHPELRRVYFNKGL :::::::::::::::::::::: CCDS43 ELQAKIQESHPELRRVYFNKGL 310 320 >>CCDS7508.2 SFXN3 gene_id:81855|Hs108|chr10 (325 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 2251.7 bits: 424.9 E(32554): 4.2e-119 Smith-Waterman score: 1729; 76.6% identity (94.1% similar) in 320 aa overlap (3-322:6-325) 10 20 30 40 50 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQG :::: .:::.:::::::::.::: ::::::::::.::.. :::..:.::..:: : CCDS75 MESKMGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 IVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAV .: ::.::..::::::.::::::::::::..:::::::::::::::::::.:::: ::.: CCDS75 VVTPGITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 LFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIG .::::.::::::.:::.:::::.:.:: .:::::::::::::::::::..::::. ::.: CCDS75 VFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLTKHLPPLVG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 RFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMA ::::::::::::::::::::::::.:::::.:: :.::: :..::::.: :::.::: :: CCDS75 RFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 APGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTS :.:::::.::.::::: :::: ::..::.:::::::::::::::::::::::::. ... CCDS75 IPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISN 250 260 270 280 290 300 300 310 320 pF1KE0 LEAELQAKIQESHPELRRVYFNKGL :: ::.:.:.:..: .. ::.:::: CCDS75 LEPELRAQIHEQNPSVEVVYYNKGL 310 320 >>CCDS7539.1 SFXN2 gene_id:118980|Hs108|chr10 (322 aa) initn: 1191 init1: 1158 opt: 1192 Z-score: 1552.6 bits: 295.5 E(32554): 3.7e-80 Smith-Waterman score: 1192; 56.1% identity (79.3% similar) in 314 aa overlap (10-322:9-322) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :: ::::: ::.::..::...::::........:. :. .:. :.:.:: CCDS75 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVP 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :: ..: :: .::::::::::::: .::::: :.: .: ::: :. :::: :::.:: CCDS75 PGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFW 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV ::.::::::.::::::.. .: .: ... .: .::: :::::.:.: :::.. ::.::.: CCDS75 QWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG ::::::::::.:::.:::.:: :: : :.: :..:.: :: .:::::.::: :.::: CCDS75 PFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA : . : ::. ::: :... . ::.:: : : :.: .:. :.::::: . :. :: CCDS75 MILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEP 240 250 260 270 280 290 310 320 pF1KE0 ELQAKIQESHPELR-RVYFNKGL .:: :. .. ::. ::::::: CCDS75 KLQDTIKAKYGELEPYVYFNKGL 300 310 320 >>CCDS1922.1 SFXN5 gene_id:94097|Hs108|chr2 (340 aa) initn: 818 init1: 439 opt: 783 Z-score: 1019.8 bits: 197.0 E(32554): 1.8e-50 Smith-Waterman score: 785; 39.1% identity (71.5% similar) in 330 aa overlap (2-322:19-340) 10 20 30 40 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQ :.. :: ... .::..:..: :: ::. . :::....:... CCDS19 MADTATTASAAAASAASASSDAPP-FQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERR 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 LESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTI :. : ....::..: . ::.:...:: :. : .. .::::.::... :::. .:.. : CCDS19 LREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPI 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 TGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATAL . .. .: ...::::.::: :: :::.::.. : .... .:..:. .::. :. CCDS19 VVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAV 120 130 140 150 160 170 170 180 190 200 210 pF1KE0 GLNALTKHV---SP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLG :::.:.... .: :: ::::: :::.:: :. ::: ::. :: : : .:: .: CCDS19 GLNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVG 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 ESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQ--VGLVGF : ::..:. .....:... : ...::..:. ::: :.:. : . :.: : :..: CCDS19 SSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLVCLAAF 240 250 260 270 280 290 280 290 300 310 320 pF1KE0 CLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL : : :: .:::: : . ...:: :. :. : : : .:::: CCDS19 GL--ALPLAISLFPQMSEIETSQLEPEI-AQATSS----RTVVYNKGL 300 310 320 330 340 >>CCDS82469.1 SFXN5 gene_id:94097|Hs108|chr2 (253 aa) initn: 532 init1: 439 opt: 501 Z-score: 654.7 bits: 129.0 E(32554): 3.8e-30 Smith-Waterman score: 501; 37.5% identity (74.5% similar) in 200 aa overlap (2-194:19-217) 10 20 30 40 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQ :.. :: ... .::..:..: :: ::. . :::....:... CCDS82 MADTATTASAAAASAASASSDAPP-FQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERR 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 LESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTI :. : ....::..: . ::.:...:: :. : .. .::::.::... :::. .:.. : CCDS82 LREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPI 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 TGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATAL . .. .: ...::::.::: :: :::.::.. : .... .:..:. .::. :. CCDS82 VVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAV 120 130 140 150 160 170 170 180 190 200 210 pF1KE0 GLNALTKHV---SP----LIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLG :::.:.... .: :: ::::: ::. .: . : CCDS82 GLNVLVQKANKFTPATRLLIQRFVPFPAVGRLSCRHAPGCSSLCKASCAWQPSAWPCRWP 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 ESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCL CCDS82 SASSRKCQRLKHPN 240 250 >>CCDS7610.1 SFXN4 gene_id:119559|Hs108|chr10 (337 aa) initn: 237 init1: 160 opt: 312 Z-score: 406.7 bits: 83.6 E(32554): 2.5e-16 Smith-Waterman score: 312; 22.0% identity (58.4% similar) in 327 aa overlap (5-322:25-337) 10 20 30 pF1KE0 MSGELPPNINIKEPRW--DQSTFIGRANHFFTVTDPRNIL . ::. . : ....:: : .. . :: :.. CCDS76 MSLEQEEETQPGRLLGRRDAVPAFIEPNVRF----WITERQSFIRRFLQWTELLDPTNVF 10 20 30 40 50 40 50 60 70 80 90 pF1KE0 LTNEQLESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVP .. :..:..:... . . :. ..... .: .. :::... . . : .: .: CCDS76 ISVESIENSRQLLCT-NEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLP 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE0 MNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGA . . :: . .:.. : . .. :. : : :. : . : . . : :: CCDS76 FMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSIN--GNRSYTCKPLERSLLMA--GA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE0 VATALGLNALTKHVS-------PLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDEN ::.. :... . :. : : :..: .. :. .:. . :. : :: : :.. CCDS76 VASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKE 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE0 GNRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGL :: ::.: :. .:. ....:::.. . . :: . ... .... : .... CCDS76 GNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSC 240 250 260 270 280 290 280 290 300 310 320 pF1KE0 VGFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL . . . . .:. ..::: .... ::: ..:. .:.. .....:. CCDS76 TVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETE-----IFYHRGV 300 310 320 330 322 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:20:15 2016 done: Thu Nov 3 22:20:15 2016 Total Scan time: 2.270 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]