FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0183, 322 aa 1>>>pF1KE0183 322 - 322 aa - 322 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9962+/-0.000392; mu= 17.3894+/- 0.024 mean_var=61.6727+/-12.687, 0's: 0 Z-trim(111.3): 59 B-trim: 467 in 2/53 Lambda= 0.163316 statistics sampled from 19860 (19921) to 19860 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.234), width: 16 Scan time: 7.180 The best scores are: opt bits E(85289) NP_073591 (OMIM: 615569) sideroflexin-1 isoform 1 ( 322) 2137 512.2 5.7e-145 NP_001309906 (OMIM: 615569) sideroflexin-1 isoform ( 322) 2137 512.2 5.7e-145 NP_112233 (OMIM: 615571) sideroflexin-3 [Homo sapi ( 325) 1729 416.1 5e-116 NP_001309911 (OMIM: 615569) sideroflexin-1 isoform ( 261) 1707 410.8 1.5e-114 NP_001309907 (OMIM: 615569) sideroflexin-1 isoform ( 261) 1707 410.8 1.5e-114 NP_001309912 (OMIM: 615569) sideroflexin-1 isoform ( 242) 1590 383.2 2.8e-106 NP_001309910 (OMIM: 615569) sideroflexin-1 isoform ( 261) 1325 320.8 1.9e-87 NP_001309909 (OMIM: 615569) sideroflexin-1 isoform ( 261) 1325 320.8 1.9e-87 NP_849189 (OMIM: 615570) sideroflexin-2 [Homo sapi ( 322) 1192 289.6 6.1e-78 XP_011537564 (OMIM: 615570) PREDICTED: sideroflexi ( 322) 1192 289.6 6.1e-78 XP_011537563 (OMIM: 615570) PREDICTED: sideroflexi ( 331) 1192 289.6 6.2e-78 NP_653180 (OMIM: 615572) sideroflexin-5 isoform 2 ( 340) 783 193.2 6.5e-49 XP_011537566 (OMIM: 615570) PREDICTED: sideroflexi ( 210) 775 191.2 1.6e-48 XP_011537565 (OMIM: 615570) PREDICTED: sideroflexi ( 210) 775 191.2 1.6e-48 XP_016860829 (OMIM: 615572) PREDICTED: sideroflexi ( 350) 744 184.0 3.9e-46 NP_001317329 (OMIM: 615572) sideroflexin-5 isoform ( 357) 744 184.0 3.9e-46 XP_011531490 (OMIM: 615572) PREDICTED: sideroflexi ( 367) 705 174.8 2.4e-43 NP_001317331 (OMIM: 615572) sideroflexin-5 isoform ( 281) 674 167.5 3e-41 NP_001317335 (OMIM: 615572) sideroflexin-5 isoform ( 321) 669 166.3 7.5e-41 XP_011531489 (OMIM: 615572) PREDICTED: sideroflexi ( 397) 669 166.4 9e-41 XP_016860830 (OMIM: 615572) PREDICTED: sideroflexi ( 291) 635 158.3 1.8e-38 XP_011531494 (OMIM: 615572) PREDICTED: sideroflexi ( 338) 628 156.7 6.4e-38 XP_011531492 (OMIM: 615572) PREDICTED: sideroflexi ( 355) 628 156.7 6.6e-38 XP_011531488 (OMIM: 615572) PREDICTED: sideroflexi ( 414) 628 156.7 7.5e-38 XP_016871152 (OMIM: 615570) PREDICTED: sideroflexi ( 186) 583 145.9 6.1e-35 NP_001317334 (OMIM: 615572) sideroflexin-5 isoform ( 262) 558 140.1 4.8e-33 XP_011531496 (OMIM: 615572) PREDICTED: sideroflexi ( 338) 558 140.2 5.9e-33 NP_001317333 (OMIM: 615572) sideroflexin-5 isoform ( 236) 535 134.7 1.9e-31 NP_001317339 (OMIM: 615572) sideroflexin-5 isoform ( 236) 535 134.7 1.9e-31 NP_001317330 (OMIM: 615572) sideroflexin-5 isoform ( 253) 501 126.7 5.1e-29 XP_011531498 (OMIM: 615572) PREDICTED: sideroflexi ( 253) 496 125.5 1.2e-28 NP_001317336 (OMIM: 615572) sideroflexin-5 isoform ( 253) 496 125.5 1.2e-28 NP_001317337 (OMIM: 615572) sideroflexin-5 isoform ( 177) 424 108.4 1.1e-23 NP_001317332 (OMIM: 615572) sideroflexin-5 isoform ( 234) 385 99.3 8.1e-21 XP_011531497 (OMIM: 615572) PREDICTED: sideroflexi ( 310) 385 99.4 1e-20 NP_998814 (OMIM: 615564,615578) sideroflexin-4 [Ho ( 337) 312 82.2 1.6e-15 XP_005264705 (OMIM: 615572) PREDICTED: sideroflexi ( 189) 307 80.9 2.3e-15 NP_001317341 (OMIM: 615572) sideroflexin-5 isoform ( 189) 307 80.9 2.3e-15 NP_001317340 (OMIM: 615572) sideroflexin-5 isoform ( 189) 307 80.9 2.3e-15 XP_005269582 (OMIM: 615564,615578) PREDICTED: side ( 328) 291 77.3 5e-14 XP_016860835 (OMIM: 615572) PREDICTED: sideroflexi ( 206) 268 71.7 1.5e-12 XP_011531499 (OMIM: 615572) PREDICTED: sideroflexi ( 206) 268 71.7 1.5e-12 XP_016860834 (OMIM: 615572) PREDICTED: sideroflexi ( 210) 268 71.7 1.5e-12 XP_005269583 (OMIM: 615564,615578) PREDICTED: side ( 221) 226 61.8 1.5e-09 XP_005269584 (OMIM: 615564,615578) PREDICTED: side ( 221) 226 61.8 1.5e-09 XP_011537584 (OMIM: 615564,615578) PREDICTED: side ( 221) 226 61.8 1.5e-09 >>NP_073591 (OMIM: 615569) sideroflexin-1 isoform 1 [Hom (322 aa) initn: 2137 init1: 2137 opt: 2137 Z-score: 2723.6 bits: 512.2 E(85289): 5.7e-145 Smith-Waterman score: 2137; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA 250 260 270 280 290 300 310 320 pF1KE0 ELQAKIQESHPELRRVYFNKGL :::::::::::::::::::::: NP_073 ELQAKIQESHPELRRVYFNKGL 310 320 >>NP_001309906 (OMIM: 615569) sideroflexin-1 isoform 1 [ (322 aa) initn: 2137 init1: 2137 opt: 2137 Z-score: 2723.6 bits: 512.2 E(85289): 5.7e-145 Smith-Waterman score: 2137; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA 250 260 270 280 290 300 310 320 pF1KE0 ELQAKIQESHPELRRVYFNKGL :::::::::::::::::::::: NP_001 ELQAKIQESHPELRRVYFNKGL 310 320 >>NP_112233 (OMIM: 615571) sideroflexin-3 [Homo sapiens] (325 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 2204.0 bits: 416.1 E(85289): 5e-116 Smith-Waterman score: 1729; 76.6% identity (94.1% similar) in 320 aa overlap (3-322:6-325) 10 20 30 40 50 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQG :::: .:::.:::::::::.::: ::::::::::.::.. :::..:.::..:: : NP_112 MESKMGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 IVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAV .: ::.::..::::::.::::::::::::..:::::::::::::::::::.:::: ::.: NP_112 VVTPGITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 LFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIG .::::.::::::.:::.:::::.:.:: .:::::::::::::::::::..::::. ::.: NP_112 VFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLTKHLPPLVG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 RFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMA ::::::::::::::::::::::::.:::::.:: :.::: :..::::.: :::.::: :: NP_112 RFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 APGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTS :.:::::.::.::::: :::: ::..::.:::::::::::::::::::::::::. ... NP_112 IPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISN 250 260 270 280 290 300 300 310 320 pF1KE0 LEAELQAKIQESHPELRRVYFNKGL :: ::.:.:.:..: .. ::.:::: NP_112 LEPELRAQIHEQNPSVEVVYYNKGL 310 320 >>NP_001309911 (OMIM: 615569) sideroflexin-1 isoform 2 [ (261 aa) initn: 1707 init1: 1707 opt: 1707 Z-score: 2177.4 bits: 410.8 E(85289): 1.5e-114 Smith-Waterman score: 1707; 99.6% identity (100.0% similar) in 260 aa overlap (63-322:2-261) 40 50 60 70 80 90 pF1KE0 DPRNILLTNEQLESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGR .::::::::::::::::::::::::::::: NP_001 MITENELWRAKYIYDSAFHPDTGEKMILIGR 10 20 30 100 110 120 130 140 150 pF1KE0 MSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYV 40 50 60 70 80 90 160 170 180 190 200 210 pF1KE0 SATTGAVATALGLNALTKHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SATTGAVATALGLNALTKHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KE0 NRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLV 160 170 180 190 200 210 280 290 300 310 320 pF1KE0 GFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL 220 230 240 250 260 >>NP_001309907 (OMIM: 615569) sideroflexin-1 isoform 2 [ (261 aa) initn: 1707 init1: 1707 opt: 1707 Z-score: 2177.4 bits: 410.8 E(85289): 1.5e-114 Smith-Waterman score: 1707; 99.6% identity (100.0% similar) in 260 aa overlap (63-322:2-261) 40 50 60 70 80 90 pF1KE0 DPRNILLTNEQLESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGR .::::::::::::::::::::::::::::: NP_001 MITENELWRAKYIYDSAFHPDTGEKMILIGR 10 20 30 100 110 120 130 140 150 pF1KE0 MSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYV 40 50 60 70 80 90 160 170 180 190 200 210 pF1KE0 SATTGAVATALGLNALTKHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SATTGAVATALGLNALTKHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KE0 NRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLV 160 170 180 190 200 210 280 290 300 310 320 pF1KE0 GFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL 220 230 240 250 260 >>NP_001309912 (OMIM: 615569) sideroflexin-1 isoform 3 [ (242 aa) initn: 1590 init1: 1590 opt: 1590 Z-score: 2028.9 bits: 383.2 E(85289): 2.8e-106 Smith-Waterman score: 1590; 100.0% identity (100.0% similar) in 241 aa overlap (1-241:1-241) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA : NP_001 MG >>NP_001309910 (OMIM: 615569) sideroflexin-1 isoform 4 [ (261 aa) initn: 1349 init1: 1325 opt: 1325 Z-score: 1691.0 bits: 320.8 E(85289): 1.9e-87 Smith-Waterman score: 1325; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG :::::::::::::::::: NP_001 PFAAVAAANCINIPLMRQSHPSIHYEHFGKESLFEEVPMDECTHSSWVSWLLFGVCYTPV 190 200 210 220 230 240 >>NP_001309909 (OMIM: 615569) sideroflexin-1 isoform 4 [ (261 aa) initn: 1349 init1: 1325 opt: 1325 Z-score: 1691.0 bits: 320.8 E(85289): 1.9e-87 Smith-Waterman score: 1325; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG :::::::::::::::::: NP_001 PFAAVAAANCINIPLMRQSHPSIHYEHFGKESLFEEVPMDECTHSSWVSWLLFGVCYTPV 190 200 210 220 230 240 >>NP_849189 (OMIM: 615570) sideroflexin-2 [Homo sapiens] (322 aa) initn: 1191 init1: 1158 opt: 1192 Z-score: 1520.3 bits: 289.6 E(85289): 6.1e-78 Smith-Waterman score: 1192; 56.1% identity (79.3% similar) in 314 aa overlap (10-322:9-322) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :: ::::: ::.::..::...::::........:. :. .:. :.:.:: NP_849 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVP 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :: ..: :: .::::::::::::: .::::: :.: .: ::: :. :::: :::.:: NP_849 PGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFW 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV ::.::::::.::::::.. .: .: ... .: .::: :::::.:.: :::.. ::.::.: NP_849 QWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG ::::::::::.:::.:::.:: :: : :.: :..:.: :: .:::::.::: :.::: NP_849 PFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA : . : ::. ::: :... . ::.:: : : :.: .:. :.::::: . :. :: NP_849 MILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEP 240 250 260 270 280 290 310 320 pF1KE0 ELQAKIQESHPELR-RVYFNKGL .:: :. .. ::. ::::::: NP_849 KLQDTIKAKYGELEPYVYFNKGL 300 310 320 >>XP_011537564 (OMIM: 615570) PREDICTED: sideroflexin-2 (322 aa) initn: 1191 init1: 1158 opt: 1192 Z-score: 1520.3 bits: 289.6 E(85289): 6.1e-78 Smith-Waterman score: 1192; 56.1% identity (79.3% similar) in 314 aa overlap (10-322:9-322) 10 20 30 40 50 60 pF1KE0 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP :: ::::: ::.::..::...::::........:. :. .:. :.:.:: XP_011 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVP 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW :: ..: :: .::::::::::::: .::::: :.: .: ::: :. :::: :::.:: XP_011 PGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFW 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV ::.::::::.::::::.. .: .: ... .: .::: :::::.:.: :::.. ::.::.: XP_011 QWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG ::::::::::.:::.:::.:: :: : :.: :..:.: :: .:::::.::: :.::: XP_011 PFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA : . : ::. ::: :... . ::.:: : : :.: .:. :.::::: . :. :: XP_011 MILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEP 240 250 260 270 280 290 310 320 pF1KE0 ELQAKIQESHPELR-RVYFNKGL .:: :. .. ::. ::::::: XP_011 KLQDTIKAKYGELEPYVYFNKGL 300 310 320 322 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:20:15 2016 done: Thu Nov 3 22:20:16 2016 Total Scan time: 7.180 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]