FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0184, 286 aa 1>>>pF1KE0184 286 - 286 aa - 286 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3212+/-0.000806; mu= 15.0256+/- 0.048 mean_var=62.0949+/-12.382, 0's: 0 Z-trim(106.9): 17 B-trim: 0 in 0/50 Lambda= 0.162759 statistics sampled from 9259 (9264) to 9259 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.285), width: 16 Scan time: 2.450 The best scores are: opt bits E(32554) CCDS5521.1 GBAS gene_id:2631|Hs108|chr7 ( 286) 1991 475.9 1.5e-134 CCDS13860.1 NIPSNAP1 gene_id:8508|Hs108|chr22 ( 284) 1383 333.1 1.4e-91 CCDS56488.1 GBAS gene_id:2631|Hs108|chr7 ( 247) 966 235.2 3.7e-62 CCDS6761.1 NIPSNAP3B gene_id:55335|Hs108|chr9 ( 247) 253 67.7 9.3e-12 CCDS6760.1 NIPSNAP3A gene_id:25934|Hs108|chr9 ( 247) 244 65.6 4e-11 >>CCDS5521.1 GBAS gene_id:2631|Hs108|chr7 (286 aa) initn: 1991 init1: 1991 opt: 1991 Z-score: 2529.2 bits: 475.9 E(32554): 1.5e-134 Smith-Waterman score: 1991; 100.0% identity (100.0% similar) in 286 aa overlap (1-286:1-286) 10 20 30 40 50 60 pF1KE0 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR 190 200 210 220 230 240 250 260 270 280 pF1KE0 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ :::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ 250 260 270 280 >>CCDS13860.1 NIPSNAP1 gene_id:8508|Hs108|chr22 (284 aa) initn: 1383 init1: 1383 opt: 1383 Z-score: 1757.7 bits: 333.1 E(32554): 1.4e-91 Smith-Waterman score: 1383; 75.5% identity (93.2% similar) in 249 aa overlap (38-286:36-284) 10 20 30 40 50 60 pF1KE0 ARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAK ... : ::..::::.::::::::::.::.: CCDS13 CSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHL ::::::::.:::::::: :.:::.. . ::::.: :. :::.:::.:::::::::::::: CCDS13 KETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 WRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIY ::. :::::: . ::::..:::.::::. ::.:::::.::::::::::::: :: ::::: CCDS13 WRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTRED :::.:.:.::::::::: :::::..::...:::::::::::.::.:::::::.:::.::. CCDS13 ELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREE 190 200 210 220 230 240 250 260 270 280 pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ :::::.:.::.: :::::::...:::::::::: :::: CCDS13 TRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ 250 260 270 280 >>CCDS56488.1 GBAS gene_id:2631|Hs108|chr7 (247 aa) initn: 1467 init1: 966 opt: 966 Z-score: 1229.4 bits: 235.2 E(32554): 3.7e-62 Smith-Waterman score: 1420; 79.7% identity (83.6% similar) in 286 aa overlap (1-286:1-247) 10 20 30 40 50 60 pF1KE0 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE ::::::::::::::::::. .: ::. . ::. ::: :.: CCDS56 HSNLLAKKETSNLYKLQFK----RC-------CQR-FTKINT------TLV----LWWGL 70 80 90 130 140 150 160 170 180 pF1KE0 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP . :. . :.. :::::::::::::::::::::::::::::::: CCDS56 GTR---------GMASRTKL--------EFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR 150 160 170 180 190 200 250 260 270 280 pF1KE0 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ :::::::::::::::::::::::::::::::::::::::::::::: CCDS56 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ 210 220 230 240 >>CCDS6761.1 NIPSNAP3B gene_id:55335|Hs108|chr9 (247 aa) initn: 190 init1: 115 opt: 253 Z-score: 324.6 bits: 67.7 E(32554): 9.3e-12 Smith-Waterman score: 253; 26.1% identity (55.4% similar) in 249 aa overlap (47-286:10-247) 20 30 40 50 60 70 pF1KE0 LLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKL :.: : . :. . .. ...:.. CCDS67 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEF 10 20 30 80 90 100 110 120 130 pF1KE0 QFHNVKPECLEAYNKICQEVLPK-IHEDKHYPCTLVGTWNTWYG-EQDQAVHLWRYEGGY . . .:: ..:. .: : : :: : ::: :.. .: . ... :.:.:.. . CCDS67 RTYYLKPSNMNAF----MENLKKNIHLRTSYS-ELVGFWSVEFGGRTNKVFHIWKYDN-F 40 50 60 70 80 90 140 150 160 170 180 pF1KE0 PALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSF---WN--EPVPRSGPNIYEL .:: . : . ::. : . :.: .. :... :. : :. : .::: CCDS67 AHRAEVRKALANCKEWQEQSIIPN---LARIDKQETEITYLIPWSKLEKPPKEG--VYEL 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 RSYQLRPGTMIEWGNYWARAIRFRQD-G-NEAVGGFFSQIGQLYMVHHLWAYRDLQTRED .:..:: ::. . ::: . . : ...:: : .. :.: :: :: .. ..: CCDS67 AVFQMKPGGPALWGDAFERAINAHVNLGYTKVVGVFHTEYGELNRVHVLWWNESADSRAA 150 160 170 180 190 200 250 260 270 280 pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ :. . . : .: . ... ..:: . :::. CCDS67 GRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPASFSPLK 210 220 230 240 >>CCDS6760.1 NIPSNAP3A gene_id:25934|Hs108|chr9 (247 aa) initn: 204 init1: 131 opt: 244 Z-score: 313.2 bits: 65.6 E(32554): 4e-11 Smith-Waterman score: 244; 24.5% identity (54.6% similar) in 249 aa overlap (47-286:10-247) 20 30 40 50 60 70 pF1KE0 LLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKL ..: : . :. . .. . .:.. CCDS67 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEF 10 20 30 80 90 100 110 120 130 pF1KE0 QFHNVKP----ECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYG-EQDQAVHLWRYE . . .:: : :: ..: . : : . ::: :.. .: ... . :.:.:. CCDS67 RSYYLKPSKMNEFLENFEKNAH--LRTAHSE------LVGYWSVEFGGRMNTVFHIWKYD 40 50 60 70 80 90 140 150 160 170 180 pF1KE0 GGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWN--EPVPRSGPNIYEL . . ::: . : ..::. : . :...... . . : : :. : .::: CCDS67 N-FAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPWCKLEKPPKEG--VYEL 100 110 120 130 140 190 200 210 220 230 240 pF1KE0 RSYQLRPGTMIEWGNYWARAIRFRQD-G-NEAVGGFFSQIGQLYMVHHLWAYRDLQTRED ..:..:: ::. . ::.. . . : .. :: : .. : : :: :: .. ..: CCDS67 ATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAA 150 160 170 180 190 200 250 260 270 280 pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ :. . . : .: . ... ..:: . :::. CCDS67 GRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSPLK 210 220 230 240 286 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:18:12 2016 done: Thu Nov 3 22:18:13 2016 Total Scan time: 2.450 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]