Result of FASTA (omim) for
pF1KE0184
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0184, 286 aa
1>>>pF1KE0184 286 - 286 aa - 286 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2344+/-0.000367; mu= 15.7491+/- 0.023
mean_var=67.7105+/-13.332, 0's: 0 Z-trim(113.4): 11 B-trim: 0 in 0/55
Lambda= 0.155864
statistics sampled from 22723 (22734) to 22723 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.267), width: 16
Scan time: 6.930
The best scores are: opt bits E(85289)
NP_001474 (OMIM: 603004) protein NipSnap homolog 2 ( 286) 1991 456.6 2.5e-128
NP_001189431 (OMIM: 603249) protein NipSnap homolo ( 264) 1388 321.0 1.6e-87
NP_003625 (OMIM: 603249) protein NipSnap homolog 1 ( 284) 1383 319.8 3.6e-87
NP_001189398 (OMIM: 603004) protein NipSnap homolo ( 247) 966 226.0 5.4e-59
NP_060846 (OMIM: 608872) protein NipSnap homolog 3 ( 247) 253 65.7 1e-10
NP_056284 (OMIM: 608871) protein NipSnap homolog 3 ( 247) 244 63.7 4.1e-10
XP_016870378 (OMIM: 608872) PREDICTED: protein Nip ( 231) 231 60.7 2.9e-09
NP_001316499 (OMIM: 608871) protein NipSnap homolo ( 197) 176 48.3 1.4e-05
>>NP_001474 (OMIM: 603004) protein NipSnap homolog 2 iso (286 aa)
initn: 1991 init1: 1991 opt: 1991 Z-score: 2424.8 bits: 456.6 E(85289): 2.5e-128
Smith-Waterman score: 1991; 100.0% identity (100.0% similar) in 286 aa overlap (1-286:1-286)
10 20 30 40 50 60
pF1KE0 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR
190 200 210 220 230 240
250 260 270 280
pF1KE0 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
250 260 270 280
>>NP_001189431 (OMIM: 603249) protein NipSnap homolog 1 (264 aa)
initn: 1383 init1: 1383 opt: 1388 Z-score: 1692.5 bits: 321.0 E(85289): 1.6e-87
Smith-Waterman score: 1388; 72.3% identity (90.9% similar) in 264 aa overlap (26-286:1-264)
10 20 30 40 50
pF1KE0 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSS---NRSREDSWLKSLFVRKVDPR
. ::: . . .. ... : ::..::::.:::::
NP_001 MAPRLCSISVTARFYSKDNEGSWFRSLFVHKVDPR
10 20 30
60 70 80 90 100 110
pF1KE0 KDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTW
:::::.::.:::::::::.:::::::: :.:::.. . ::::.: :. :::.:::.::::
NP_001 KDAHSTLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTW
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 YGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNE
::::::::::::. :::::: . ::::..:::.::::. ::.:::::.::::::::::::
NP_001 YGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 PVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLW
: :: ::::::::.:.:.::::::::: :::::..::...:::::::::::.::.:::::
NP_001 PQPRMGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLW
160 170 180 190 200 210
240 250 260 270 280
pF1KE0 AYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
::.:::.::. :::::.:.::.: :::::::...:::::::::: ::::
NP_001 AYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ
220 230 240 250 260
>>NP_003625 (OMIM: 603249) protein NipSnap homolog 1 iso (284 aa)
initn: 1383 init1: 1383 opt: 1383 Z-score: 1686.0 bits: 319.8 E(85289): 3.6e-87
Smith-Waterman score: 1383; 75.5% identity (93.2% similar) in 249 aa overlap (38-286:36-284)
10 20 30 40 50 60
pF1KE0 ARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAK
... : ::..::::.::::::::::.::.:
NP_003 CSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHL
::::::::.:::::::: :.:::.. . ::::.: :. :::.:::.::::::::::::::
NP_003 KETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 WRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIY
::. :::::: . ::::..:::.::::. ::.:::::.::::::::::::: :: :::::
NP_003 WRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTRED
:::.:.:.::::::::: :::::..::...:::::::::::.::.:::::::.:::.::.
NP_003 ELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREE
190 200 210 220 230 240
250 260 270 280
pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
:::::.:.::.: :::::::...:::::::::: ::::
NP_003 TRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ
250 260 270 280
>>NP_001189398 (OMIM: 603004) protein NipSnap homolog 2 (247 aa)
initn: 1467 init1: 966 opt: 966 Z-score: 1180.1 bits: 226.0 E(85289): 5.4e-59
Smith-Waterman score: 1420; 79.7% identity (83.6% similar) in 286 aa overlap (1-286:1-247)
10 20 30 40 50 60
pF1KE0 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE
::::::::::::::::::. .: ::. . ::. ::: :.:
NP_001 HSNLLAKKETSNLYKLQFK----RC-------CQR-FTKINT------TLV----LWWGL
70 80 90
130 140 150 160 170 180
pF1KE0 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
. :. . :.. ::::::::::::::::::::::::::::::::
NP_001 GTR---------GMASRTKL--------EFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
100 110 120 130 140
190 200 210 220 230 240
pF1KE0 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR
150 160 170 180 190 200
250 260 270 280
pF1KE0 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
210 220 230 240
>>NP_060846 (OMIM: 608872) protein NipSnap homolog 3B [H (247 aa)
initn: 190 init1: 115 opt: 253 Z-score: 313.6 bits: 65.7 E(85289): 1e-10
Smith-Waterman score: 253; 26.1% identity (55.4% similar) in 249 aa overlap (47-286:10-247)
20 30 40 50 60 70
pF1KE0 LLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKL
:.: : . :. . .. ...:..
NP_060 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEF
10 20 30
80 90 100 110 120 130
pF1KE0 QFHNVKPECLEAYNKICQEVLPK-IHEDKHYPCTLVGTWNTWYG-EQDQAVHLWRYEGGY
. . .:: ..:. .: : : :: : ::: :.. .: . ... :.:.:.. .
NP_060 RTYYLKPSNMNAF----MENLKKNIHLRTSYS-ELVGFWSVEFGGRTNKVFHIWKYDN-F
40 50 60 70 80 90
140 150 160 170 180
pF1KE0 PALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSF---WN--EPVPRSGPNIYEL
.:: . : . ::. : . :.: .. :... :. : :. : .:::
NP_060 AHRAEVRKALANCKEWQEQSIIPN---LARIDKQETEITYLIPWSKLEKPPKEG--VYEL
100 110 120 130 140
190 200 210 220 230 240
pF1KE0 RSYQLRPGTMIEWGNYWARAIRFRQD-G-NEAVGGFFSQIGQLYMVHHLWAYRDLQTRED
.:..:: ::. . ::: . . : ...:: : .. :.: :: :: .. ..:
NP_060 AVFQMKPGGPALWGDAFERAINAHVNLGYTKVVGVFHTEYGELNRVHVLWWNESADSRAA
150 160 170 180 190 200
250 260 270 280
pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
:. . . : .: . ... ..:: . :::.
NP_060 GRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPASFSPLK
210 220 230 240
>>NP_056284 (OMIM: 608871) protein NipSnap homolog 3A is (247 aa)
initn: 204 init1: 131 opt: 244 Z-score: 302.6 bits: 63.7 E(85289): 4.1e-10
Smith-Waterman score: 244; 24.5% identity (54.6% similar) in 249 aa overlap (47-286:10-247)
20 30 40 50 60 70
pF1KE0 LLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKL
..: : . :. . .. . .:..
NP_056 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEF
10 20 30
80 90 100 110 120 130
pF1KE0 QFHNVKP----ECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYG-EQDQAVHLWRYE
. . .:: : :: ..: . : : . ::: :.. .: ... . :.:.:.
NP_056 RSYYLKPSKMNEFLENFEKNAH--LRTAHSE------LVGYWSVEFGGRMNTVFHIWKYD
40 50 60 70 80 90
140 150 160 170 180
pF1KE0 GGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWN--EPVPRSGPNIYEL
. . ::: . : ..::. : . :...... . . : : :. : .:::
NP_056 N-FAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPWCKLEKPPKEG--VYEL
100 110 120 130 140
190 200 210 220 230 240
pF1KE0 RSYQLRPGTMIEWGNYWARAIRFRQD-G-NEAVGGFFSQIGQLYMVHHLWAYRDLQTRED
..:..:: ::. . ::.. . . : .. :: : .. : : :: :: .. ..:
NP_056 ATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAA
150 160 170 180 190 200
250 260 270 280
pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
:. . . : .: . ... ..:: . :::.
NP_056 GRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSPLK
210 220 230 240
>>XP_016870378 (OMIM: 608872) PREDICTED: protein NipSnap (231 aa)
initn: 163 init1: 115 opt: 231 Z-score: 287.3 bits: 60.7 E(85289): 2.9e-09
Smith-Waterman score: 231; 28.0% identity (55.0% similar) in 218 aa overlap (47-255:10-212)
20 30 40 50 60 70
pF1KE0 LLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKL
:.: : . :. . .. ...:..
XP_016 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEF
10 20 30
80 90 100 110 120 130
pF1KE0 QFHNVKPECLEAYNKICQEVLPK-IHEDKHYPCTLVGTWNTWYG-EQDQAVHLWRYEGGY
. . .:: ..:. .: : : :: : ::: :.. .: . ... :.:.:.. .
XP_016 RTYYLKPSNMNAF----MENLKKNIHLRTSYS-ELVGFWSVEFGGRTNKVFHIWKYDN-F
40 50 60 70 80 90
140 150 160 170 180
pF1KE0 PALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSF---WN--EPVPRSGPNIYEL
.:: . : . ::. : . :.: .. :... :. : :. : .:::
XP_016 AHRAEVRKALANCKEWQEQSIIPN---LARIDKQETEITYLIPWSKLEKPPKEG--VYEL
100 110 120 130 140
190 200 210 220 230 240
pF1KE0 RSYQLRPGTMIEWGNYWARAIRFRQD-G-NEAVGGFFSQIGQLYMVHHLWAYRDLQTRED
.:..:: ::. . ::: . . : ...:: : .. :.: :: :: . :
XP_016 AVFQMKPGGPALWGDAFERAINAHVNLGYTKVVGVFHTEYGELNRVHVLW----WNESAD
150 160 170 180 190 200
250 260 270 280
pF1KE0 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
: :. ::
XP_016 SRAAGRHKSHEDPRVVAAGRETDMQPI
210 220 230
>>NP_001316499 (OMIM: 608871) protein NipSnap homolog 3A (197 aa)
initn: 124 init1: 78 opt: 176 Z-score: 221.4 bits: 48.3 E(85289): 1.4e-05
Smith-Waterman score: 176; 29.6% identity (58.5% similar) in 135 aa overlap (151-279:2-133)
130 140 150 160 170 180
pF1KE0 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
: .:.: . : :: . :: . :
NP_001 MLVLRSALTRALASRTLAPQMCSSFATGPRQ
10 20 30
190 200 210 220 230
pF1KE0 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIG-QLYMVHHLWAY
.: .::.::: :.:. : :. . . . ..: .: :: . ..: .. : :.: :
NP_001 YDGI-FYEFRSYYLKPSKMNEFLENFEKNAHLRTAHSELVGYWSVEFGGRMNTVFHIWKY
40 50 60 70 80 90
240 250 260 270 280
pF1KE0 RDLQTREDIRNAAWHKHGWEELVYYTVP---LIQEMESRI--MIPLKTSPLQ
.. : ..:.: . . :.: . .: ::...::.: ..:
NP_001 DNFAHRTEVRKALAKDKEWQE--QFLIPNLALIDKQESEITYLVPWCKLEKPPKEVHVLW
100 110 120 130 140
NP_001 WNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSPLK
150 160 170 180 190
286 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:18:13 2016 done: Thu Nov 3 22:18:14 2016
Total Scan time: 6.930 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]