Result of FASTA (ccds) for
pF1KE0185
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0185, 256 aa
1>>>pF1KE0185 256 - 256 aa - 256 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7047+/-0.000906; mu= 9.7188+/- 0.055
mean_var=131.0337+/-26.725, 0's: 0 Z-trim(110.6): 77 B-trim: 0 in 0/50
Lambda= 0.112042
statistics sampled from 11637 (11714) to 11637 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.36), width: 16
Scan time: 2.130
The best scores are: opt bits E(32554)
CCDS7413.1 PCGF5 gene_id:84333|Hs108|chr10 ( 256) 1795 300.9 5.7e-82
CCDS1946.2 PCGF1 gene_id:84759|Hs108|chr2 ( 259) 504 92.2 3.8e-19
CCDS31275.1 PCGF6 gene_id:84108|Hs108|chr10 ( 350) 485 89.2 4e-18
CCDS7138.1 BMI1 gene_id:648|Hs108|chr10 ( 326) 474 87.4 1.3e-17
CCDS59213.1 BMI1 gene_id:100532731|Hs108|chr10 ( 469) 474 87.6 1.7e-17
CCDS32638.1 PCGF2 gene_id:7703|Hs108|chr17 ( 344) 463 85.7 4.6e-17
CCDS3339.2 PCGF3 gene_id:10336|Hs108|chr4 ( 242) 382 72.5 3.1e-13
>>CCDS7413.1 PCGF5 gene_id:84333|Hs108|chr10 (256 aa)
initn: 1795 init1: 1795 opt: 1795 Z-score: 1585.1 bits: 300.9 E(32554): 5.7e-82
Smith-Waterman score: 1795; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256)
10 20 30 40 50 60
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLY
190 200 210 220 230 240
250
pF1KE0 QSYPMVLQYRPRIDFG
::::::::::::::::
CCDS74 QSYPMVLQYRPRIDFG
250
>>CCDS1946.2 PCGF1 gene_id:84759|Hs108|chr2 (259 aa)
initn: 462 init1: 363 opt: 504 Z-score: 457.2 bits: 92.2 E(32554): 3.8e-19
Smith-Waterman score: 504; 35.7% identity (71.4% similar) in 213 aa overlap (9-215:38-241)
10 20 30
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTF
.::.: .:.: .: ::.. ::.:::::::
CCDS19 QIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 CKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFW
::.:::.... :. :: :. ..:::.:: :.:: ....:..::::::...: .: ::.
CCDS19 CKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 KKNKPQENGQDDTSK--ADKPKVDEEG----DENEDDKDYHRSDPQIAICLDCLRNNGQS
: : : ... ...: ... : . ... :.: : :. .::. : ..:..
CCDS19 -----QSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERL-SSGKD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 GDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYM
.. : :..:..:::.:. : ... : .: : . ....: ..:.. ::. :..
CCDS19 KNKSV--LQNKYVRCSVRAEVRHLRRVLCHRLML-NPQHVQLLFDNEVLPDHMTMKQIWL
190 200 210 220 230
220 230 240 250
pF1KE0 TRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRPRIDFG
.::
CCDS19 SRWFGKPSPLLLQYSVKEKRR
240 250
>>CCDS31275.1 PCGF6 gene_id:84108|Hs108|chr10 (350 aa)
initn: 505 init1: 369 opt: 485 Z-score: 438.9 bits: 89.2 E(32554): 4e-18
Smith-Waterman score: 486; 37.1% identity (62.9% similar) in 240 aa overlap (9-247:125-344)
10 20 30
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTF
.....::: : ::::::: ::.:::::::
CCDS31 EEEEEDMSHFSLRLEGGRQDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTF
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE0 CKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFW
::.:::.:: :: ::.:. ::.:.:: .::: :..:..::: .:.:.: .. .:.
CCDS31 CKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFY
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE0 KKNKPQENGQDDTSKA-DKPKVDEEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVV
: : : . . : .: . .: .. .. : :.. . : ... : .
CCDS31 K-----ERGLEVPKPAVPQPVPSSKGRSKKVLESVFRIPPELDMSLLLEFIGANEGTGHF
220 230 240 250 260
160 170 180 190 200 210
pF1KE0 KGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRL
: : :::.: : ..:.: ..::: :. : . ..:..:. :: .: :.: ..
CCDS31 KPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICG------DHLLE-QYQTLREI
270 280 290 300 310 320
220 230 240 250
pF1KE0 RGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRPRIDFG
: : .. .: : :: : : .:.
CCDS31 R----RAIGDAAMQ----DGLLVLHYGLVVSPLKIT
330 340 350
>>CCDS7138.1 BMI1 gene_id:648|Hs108|chr10 (326 aa)
initn: 448 init1: 357 opt: 474 Z-score: 429.7 bits: 87.4 E(32554): 1.3e-17
Smith-Waterman score: 474; 33.7% identity (63.4% similar) in 246 aa overlap (9-237:9-242)
10 20 30 40 50 60
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV
. ..::.. : .: ::.: ::. ::::.:::::::...: :. :: : ::
CCDS71 MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKV-
:.: :: .: :.::..:..:::::: ..:..:. .:. . :. .. . :. :. .:
CCDS71 HKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAH-PSADAANG-SNEDRGEVA
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 DEEGDENEDDK---------DYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTR
::. ::. : .: : .. ... .: ..: :...:: .
CCDS71 DEDKRIITDDEIISLSIEFFDQNRLDRKVN------KDKEKSKEEVND---KRYLRCPAA
120 130 140 150 160
180 190 200 210 220
pF1KE0 VTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDH--TMEFIYMTRWRLRGE---NFRCL
.:: ..::: :. .:.....::. . : . ::. :.. :. :: : ..:
CCDS71 MTVMHLRKFLRSKMDIPNTFQIDVMYEEEPL-KDYYTLMDIAYIYTWRRNGPLPLKYRVR
170 180 190 200 210 220
230 240 250
pF1KE0 -NCSASQVCSQ-DGPLYQSYPMVLQYRPRIDFG
.:. .. : ::
CCDS71 PTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPH
230 240 250 260 270 280
>>CCDS59213.1 BMI1 gene_id:100532731|Hs108|chr10 (469 aa)
initn: 448 init1: 357 opt: 474 Z-score: 427.5 bits: 87.6 E(32554): 1.7e-17
Smith-Waterman score: 474; 33.7% identity (63.4% similar) in 246 aa overlap (9-237:152-385)
10 20 30
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTF
. ..::.. : .: ::.: ::. ::::.:
CCDS59 HPIQRLVLVAAWNNYRIFYQAEMHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSF
130 140 150 160 170 180
40 50 60 70 80 90
pF1KE0 CKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFW
::::::...: :. :: : :::.: :: .: :.::..:..:::::: ..:..:. .:.
CCDS59 CKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFY
190 200 210 220 230 240
100 110 120 130 140
pF1KE0 KKNKPQENGQDDTSKADKPKV-DEEGDENEDDK---------DYHRSDPQIAICLDCLRN
. :. .. . :. :. .: ::. ::. : .: : .. ..
CCDS59 AAH-PSADAANG-SNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVN------KD
250 260 270 280 290
150 160 170 180 190 200
pF1KE0 NGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDH--T
. .: ..: :...:: . .:: ..::: :. .:.....::. . : . ::.
CCDS59 KEKSKEEVND---KRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPL-KDYYTL
300 310 320 330 340
210 220 230 240 250
pF1KE0 MEFIYMTRWRLRGE---NFRCL-NCSASQVCSQ-DGPLYQSYPMVLQYRPRIDFG
:.. :. :: : ..: .:. .. : ::
CCDS59 MDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIP
350 360 370 380 390 400
CCDS59 STSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG
410 420 430 440 450 460
>>CCDS32638.1 PCGF2 gene_id:7703|Hs108|chr17 (344 aa)
initn: 441 init1: 349 opt: 463 Z-score: 419.7 bits: 85.7 E(32554): 4.6e-17
Smith-Waterman score: 463; 36.4% identity (64.1% similar) in 217 aa overlap (9-219:9-221)
10 20 30 40 50 60
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV
. ..::.. : .: ::.: ::..::::.:::::::...: .. :: : ::
CCDS32 MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQV
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQE--NGQDDTSKADKPK
:.: :: .: :.::..:..:::::: ..:..:. .:. : :: :. :. .
CCDS32 HKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNG----SNEDRGE
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 V-DEEGDENEDDKDYHRSDPQIAICLDCLRNNG--QSGDNVVKGLMKKFIRCSTRVTVGT
: ..: ::. : : ...: ..::. . .:.:: . .::
CCDS32 VLEQEKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 IKKFLSLKLKLPSSYELDVLCNGEIMGKDHT-MEFIYMTRWRLRGENFRCLNCSASQVCS
. ::: :. .::.:...:: . : . . .: :.. :. :: :
CCDS32 LAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRL
180 190 200 210 220 230
240 250
pF1KE0 QDGPLYQSYPMVLQYRPRIDFG
CCDS32 TLATVPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPPATH
240 250 260 270 280 290
>>CCDS3339.2 PCGF3 gene_id:10336|Hs108|chr4 (242 aa)
initn: 739 init1: 376 opt: 382 Z-score: 351.0 bits: 72.5 E(32554): 3.1e-13
Smith-Waterman score: 687; 39.6% identity (68.3% similar) in 268 aa overlap (5-255:4-241)
10 20 30 40 50 60
pF1KE0 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV
:: . :.: .::: .:.:::: :::::::::::..:.:...:..: :: : .
CCDS33 MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVI
10 20 30 40 50
70 80 90 100
pF1KE0 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKK----------------NKPQ
:...::... : :...:..::::::.: :.... ::..: ..
CCDS33 HQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 ENGQDDTSKADKPKVDEEGDEN-EDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKK
.. .. .::: . : ..:. :.:.:::::: :..:::.: :... ..:: .:
CCDS33 DSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLEC--NSSK-----LRGLKRK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 FIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFR
.::::...:: .:::.. ::.: : :::.::: ::.:::::..:. .::::
CCDS33 WIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWR-------
180 190 200 210 220
230 240 250
pF1KE0 CLNCSASQVCSQDGPLYQSYPMVLQYRPRIDFG
... :..:.:::..:.
CCDS33 ----------------FKKAPLLLHYRPKMDLL
230 240
256 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:14:26 2016 done: Thu Nov 3 22:14:26 2016
Total Scan time: 2.130 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]