FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0194, 181 aa 1>>>pF1KE0194 181 - 181 aa - 181 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8444+/-0.000807; mu= 10.4501+/- 0.048 mean_var=73.6541+/-14.589, 0's: 0 Z-trim(107.8): 49 B-trim: 13 in 2/50 Lambda= 0.149443 statistics sampled from 9747 (9796) to 9747 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.301), width: 16 Scan time: 1.630 The best scores are: opt bits E(32554) CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 ( 181) 1184 264.0 3.5e-71 CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 ( 185) 1166 260.2 5.3e-70 CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 ( 205) 637 146.1 1.2e-35 CCDS44270.1 RGS4 gene_id:5999|Hs108|chr1 ( 302) 637 146.2 1.7e-35 CCDS1348.1 RGS16 gene_id:6004|Hs108|chr1 ( 202) 593 136.6 8.8e-33 CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 ( 180) 591 136.2 1.1e-32 CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 ( 198) 585 134.9 2.9e-32 CCDS35114.1 RGS3 gene_id:5998|Hs108|chr9 ( 311) 562 130.0 1.3e-30 CCDS6798.1 RGS3 gene_id:5998|Hs108|chr9 ( 519) 558 129.3 3.8e-30 CCDS65111.1 RGS3 gene_id:5998|Hs108|chr9 ( 591) 558 129.3 4.2e-30 CCDS6797.1 RGS3 gene_id:5998|Hs108|chr9 ( 917) 558 129.4 6.2e-30 CCDS43869.1 RGS3 gene_id:5998|Hs108|chr9 (1198) 558 129.4 7.8e-30 CCDS44272.1 RGS4 gene_id:5999|Hs108|chr1 ( 187) 545 126.3 1.1e-29 CCDS1374.1 RGS18 gene_id:64407|Hs108|chr1 ( 235) 543 125.9 1.8e-29 CCDS1377.1 RGS2 gene_id:5997|Hs108|chr1 ( 211) 532 123.5 8.3e-29 CCDS41448.1 RGS21 gene_id:431704|Hs108|chr1 ( 152) 503 117.2 4.8e-27 CCDS55652.1 RGS5 gene_id:8490|Hs108|chr1 ( 73) 466 109.1 6.3e-25 CCDS1375.2 RGS1 gene_id:5996|Hs108|chr1 ( 209) 453 106.5 1.1e-23 CCDS1376.1 RGS13 gene_id:6003|Hs108|chr1 ( 159) 416 98.4 2.2e-21 CCDS6156.1 RGS20 gene_id:8601|Hs108|chr8 ( 241) 396 94.2 6.3e-20 CCDS69482.1 RGS20 gene_id:8601|Hs108|chr8 ( 273) 396 94.2 7e-20 CCDS6155.1 RGS20 gene_id:8601|Hs108|chr8 ( 388) 396 94.3 9.5e-20 CCDS5244.1 RGS17 gene_id:26575|Hs108|chr6 ( 210) 384 91.6 3.3e-19 CCDS13555.1 RGS19 gene_id:10287|Hs108|chr20 ( 217) 358 86.0 1.7e-17 CCDS41572.1 RGS10 gene_id:6001|Hs108|chr10 ( 167) 336 81.2 3.6e-16 CCDS31294.1 RGS10 gene_id:6001|Hs108|chr10 ( 181) 336 81.2 3.8e-16 CCDS60457.1 RGS7 gene_id:6000|Hs108|chr1 ( 424) 336 81.4 8.1e-16 CCDS60458.1 RGS7 gene_id:6000|Hs108|chr1 ( 469) 336 81.4 8.8e-16 CCDS60459.1 RGS7 gene_id:6000|Hs108|chr1 ( 477) 336 81.4 8.9e-16 CCDS31071.1 RGS7 gene_id:6000|Hs108|chr1 ( 487) 336 81.4 9.1e-16 CCDS73655.1 RGS6 gene_id:9628|Hs108|chr14 ( 437) 311 76.0 3.5e-14 CCDS9808.1 RGS6 gene_id:9628|Hs108|chr14 ( 472) 311 76.0 3.7e-14 CCDS55924.1 RGS6 gene_id:9628|Hs108|chr14 ( 490) 311 76.0 3.8e-14 CCDS45764.1 RGS9 gene_id:8787|Hs108|chr17 ( 671) 311 76.1 5e-14 CCDS42373.1 RGS9 gene_id:8787|Hs108|chr17 ( 674) 311 76.1 5.1e-14 CCDS43405.1 RGS14 gene_id:10636|Hs108|chr5 ( 566) 304 74.5 1.2e-13 CCDS10403.1 RGS11 gene_id:8786|Hs108|chr16 ( 446) 283 69.9 2.3e-12 CCDS66884.1 RGS11 gene_id:8786|Hs108|chr16 ( 456) 283 69.9 2.4e-12 CCDS42088.1 RGS11 gene_id:8786|Hs108|chr16 ( 467) 283 69.9 2.4e-12 CCDS3368.1 RGS12 gene_id:6002|Hs108|chr4 ( 799) 263 65.7 7.7e-11 >>CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 (181 aa) initn: 1184 init1: 1184 opt: 1184 Z-score: 1391.4 bits: 264.0 E(32554): 3.5e-71 Smith-Waterman score: 1184; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 130 140 150 160 170 180 pF1KE0 K : CCDS12 K >>CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 (185 aa) initn: 889 init1: 850 opt: 1166 Z-score: 1370.3 bits: 260.2 E(32554): 5.3e-70 Smith-Waterman score: 1166; 97.8% identity (97.8% similar) in 185 aa overlap (1-181:1-185) 10 20 30 40 50 60 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 IQTEAPKEV----NIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFY ::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IQTEAPKEVGLWVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFY 130 140 150 160 170 180 180 pF1KE0 QELIK ::::: CCDS58 QELIK >>CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 (205 aa) initn: 622 init1: 471 opt: 637 Z-score: 753.2 bits: 146.1 E(32554): 1.2e-35 Smith-Waterman score: 637; 53.3% identity (82.8% similar) in 180 aa overlap (1-180:1-178) 10 20 30 40 50 60 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ ::::::.:: :::. ::..: .::.:::: :: . .:.: .: . :..: .:. . CCDS12 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSC-EHNSSHNKK-DKVVICQRVSQEEVKK 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF : .::..:.... :::.::.:::::.::::..:::.::.:::::::.:.. :::.::.:: CCDS12 WAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI :...: ::::.: :.. : .:..::... :: :::.: :::::: ::..:.:: .:. CCDS12 ISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV 120 130 140 150 160 170 pF1KE0 K CCDS12 NPSSCGAEKQKGAKSSADCASLVPQCA 180 190 200 >>CCDS44270.1 RGS4 gene_id:5999|Hs108|chr1 (302 aa) initn: 622 init1: 471 opt: 637 Z-score: 750.5 bits: 146.2 E(32554): 1.7e-35 Smith-Waterman score: 637; 53.3% identity (82.8% similar) in 180 aa overlap (1-180:98-275) 10 20 30 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKP ::::::.:: :::. ::..: .::.:::: CCDS44 GEEAKYAQSRSHSSSCRISFLLANSKLLNKMCKGLAGLPASCLRSAKDMKHRLGFLLQKS 70 80 90 100 110 120 40 50 60 70 80 90 pF1KE0 DSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEEN :: . .:.: .: . :..: .:. .: .::..:.... :::.::.:::::.:::: CCDS44 DSC-EHNSSHNKK-DKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEEN 130 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 LEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSS ..:::.::.:::::::.:.. :::.::.:::...: ::::.: :.. : .:..::... CCDS44 IDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITC 190 200 210 220 230 240 160 170 180 pF1KE0 FDMAQKRIHALMEKDSLPRFVRSEFYQELIK :: :::.: :::::: ::..:.:: .:. CCDS44 FDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA 250 260 270 280 290 300 >>CCDS1348.1 RGS16 gene_id:6004|Hs108|chr1 (202 aa) initn: 608 init1: 470 opt: 593 Z-score: 702.0 bits: 136.6 E(32554): 8.8e-33 Smith-Waterman score: 593; 51.1% identity (77.8% similar) in 180 aa overlap (1-179:1-180) 10 20 30 40 50 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYN-EKPEKPAKTQKTSLDEAL ::. :::.: .:::::::.: .:::.:.: . : . : : .: ... ...: CCDS13 MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE ::.:.: ::... :.:.:..:::.::::::::::.:::..:::.: .:.: .:.::.:: CCDS13 GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL :: .:::::::::: :...: :: . . :: :: . ..:::::: :::..: :..: CCDS13 FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL 130 140 150 160 170 180 180 pF1KE0 IK CCDS13 AAQASAASATLSSCSLDEPSHT 190 200 >>CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 (180 aa) initn: 569 init1: 524 opt: 591 Z-score: 700.5 bits: 136.2 E(32554): 1.1e-32 Smith-Waterman score: 591; 51.8% identity (80.7% similar) in 166 aa overlap (15-180:9-172) 10 20 30 40 50 60 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ : : .. .:: : .: :: .:.. .::.. : . : .:: . CCDS41 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATR 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF : ::.: ::...::.:.:..:::.::::::::::.:::..:: .: ::.. ::..:.::: CCDS41 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI ....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: :::.::..: .:. CCDS41 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL 120 130 140 150 160 170 pF1KE0 K CCDS41 SQSQRRLS 180 >>CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 (198 aa) initn: 569 init1: 524 opt: 585 Z-score: 692.8 bits: 134.9 E(32554): 2.9e-32 Smith-Waterman score: 585; 51.8% identity (81.1% similar) in 164 aa overlap (17-180:29-190) 10 20 30 40 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPA : .. .:: : .: :: .:.. .::.. CCDS13 MWNTLTRSLSDHPVGKDPQAMRTGQRQNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRAL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 KTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAK : . : .:: .: ::.: ::...::.:.:..:::.::::::::::.:::..:: .: :: CCDS13 K--RLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAK 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 MAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLP .. ::..:.:::....::.::::: :.. : ::: ::::. ::.:: ..:.:::::: : CCDS13 LVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYP 120 130 140 150 160 170 170 180 pF1KE0 RFVRSEFYQELIK ::.::..: .:. CCDS13 RFLRSKMYLDLLSQSQRRLS 180 190 >>CCDS35114.1 RGS3 gene_id:5998|Hs108|chr9 (311 aa) initn: 558 init1: 518 opt: 562 Z-score: 662.9 bits: 130.0 E(32554): 1.3e-30 Smith-Waterman score: 562; 52.4% identity (77.4% similar) in 168 aa overlap (13-180:138-302) 10 20 30 40 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNE ...::..: ::::. .. .: : : CCDS35 PICGPKVGGPTEMLRGMYLTRNGNLQRRHTMKEAKDMKNKLGIFRRRNESPG---APPAG 110 120 130 140 150 160 50 60 70 80 90 100 pF1KE0 KPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKK : .: :. : . .:::.: .::.::: ..:::: :..::..::::::::::.::::.:: CCDS35 KADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKK 170 180 190 200 210 220 110 120 130 140 150 160 pF1KE0 IKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALM .:: .::: :::.:. :.: .: ::::.: .:.. : :: . . ::.::::: .:: CCDS35 VKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLM 230 240 250 260 270 280 170 180 pF1KE0 EKDSLPRFVRSEFYQELIK :::: :::.::..: .:: CCDS35 EKDSYPRFLRSDLYLDLINQKKMSPPL 290 300 310 >>CCDS6798.1 RGS3 gene_id:5998|Hs108|chr9 (519 aa) initn: 558 init1: 518 opt: 558 Z-score: 654.8 bits: 129.3 E(32554): 3.8e-30 Smith-Waterman score: 558; 53.3% identity (77.0% similar) in 165 aa overlap (16-180:349-510) 10 20 30 40 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPE ::..: ::::. .. .: : : : . CCDS67 LFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPG---APPAGKAD 320 330 340 350 360 370 50 60 70 80 90 100 pF1KE0 KPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKS : :. : . .:::.: .::.::: ..:::: :..::..::::::::::.::::.::.:: CCDS67 KMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKS 380 390 400 410 420 430 110 120 130 140 150 160 pF1KE0 PAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKD .::: :::.:. :.: .: ::::.: .:.. : :: . . ::.::::: .::::: CCDS67 QSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKD 440 450 460 470 480 490 170 180 pF1KE0 SLPRFVRSEFYQELIK : :::.::..: .:: CCDS67 SYPRFLRSDLYLDLINQKKMSPPL 500 510 >>CCDS65111.1 RGS3 gene_id:5998|Hs108|chr9 (591 aa) initn: 558 init1: 518 opt: 558 Z-score: 653.9 bits: 129.3 E(32554): 4.2e-30 Smith-Waterman score: 558; 53.3% identity (77.0% similar) in 165 aa overlap (16-180:421-582) 10 20 30 40 pF1KE0 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPE ::..: ::::. .. .: : : : . CCDS65 AASPPDSKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPG---APPAGKAD 400 410 420 430 440 50 60 70 80 90 100 pF1KE0 KPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKS : :. : . .:::.: .::.::: ..:::: :..::..::::::::::.::::.::.:: CCDS65 KMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKS 450 460 470 480 490 500 110 120 130 140 150 160 pF1KE0 PAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKD .::: :::.:. :.: .: ::::.: .:.. : :: . . ::.::::: .::::: CCDS65 QSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKD 510 520 530 540 550 560 170 180 pF1KE0 SLPRFVRSEFYQELIK : :::.::..: .:: CCDS65 SYPRFLRSDLYLDLINQKKMSPPL 570 580 590 181 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:41:37 2016 done: Thu Nov 3 21:41:38 2016 Total Scan time: 1.630 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]