FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0195, 410 aa 1>>>pF1KE0195 410 - 410 aa - 410 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3590+/-0.000311; mu= 8.6943+/- 0.019 mean_var=140.6433+/-28.746, 0's: 0 Z-trim(120.8): 44 B-trim: 414 in 1/59 Lambda= 0.108147 statistics sampled from 36437 (36481) to 36437 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.428), width: 16 Scan time: 10.840 The best scores are: opt bits E(85289) NP_001192130 (OMIM: 300092) testis-specific protei ( 410) 2729 436.9 4.2e-122 NP_001577 (OMIM: 300092) testis-specific protein T ( 410) 2729 436.9 4.2e-122 XP_011529418 (OMIM: 300092) PREDICTED: testis-spec ( 472) 2729 437.0 4.7e-122 XP_011529419 (OMIM: 300092) PREDICTED: testis-spec ( 413) 2706 433.4 5.1e-121 XP_011529420 (OMIM: 300092) PREDICTED: testis-spec ( 413) 2706 433.4 5.1e-121 XP_011510886 (OMIM: 616242) PREDICTED: transmembra ( 463) 409 75.0 4.3e-13 XP_011510885 (OMIM: 616242) PREDICTED: transmembra ( 463) 409 75.0 4.3e-13 XP_016861429 (OMIM: 616242) PREDICTED: transmembra ( 463) 409 75.0 4.3e-13 XP_016861430 (OMIM: 616242) PREDICTED: transmembra ( 463) 409 75.0 4.3e-13 XP_006713616 (OMIM: 616242) PREDICTED: transmembra ( 470) 409 75.0 4.3e-13 XP_011510884 (OMIM: 616242) PREDICTED: transmembra ( 474) 409 75.0 4.4e-13 XP_006713615 (OMIM: 616242) PREDICTED: transmembra ( 480) 409 75.0 4.4e-13 XP_016861424 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_011510882 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 NP_001121696 (OMIM: 616242) transmembrane and coil ( 539) 409 75.0 4.8e-13 XP_011510883 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_016861425 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_006713613 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_016861426 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_016861427 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_016861423 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_016861428 (OMIM: 616242) PREDICTED: transmembra ( 539) 409 75.0 4.8e-13 XP_006713607 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_016861421 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_016861422 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_016861420 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_011510874 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_006713605 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_006713606 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_011510881 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_011510878 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 XP_011510875 (OMIM: 616242) PREDICTED: transmembra ( 653) 409 75.1 5.6e-13 NP_001017395 (OMIM: 616242) transmembrane and coil ( 653) 409 75.1 5.6e-13 >>NP_001192130 (OMIM: 300092) testis-specific protein TE (410 aa) initn: 2729 init1: 2729 opt: 2729 Z-score: 2313.1 bits: 436.9 E(85289): 4.2e-122 Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KE0 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP 370 380 390 400 410 >>NP_001577 (OMIM: 300092) testis-specific protein TEX28 (410 aa) initn: 2729 init1: 2729 opt: 2729 Z-score: 2313.1 bits: 436.9 E(85289): 4.2e-122 Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KE0 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILESRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSR 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP 370 380 390 400 410 >>XP_011529418 (OMIM: 300092) PREDICTED: testis-specific (472 aa) initn: 2729 init1: 2729 opt: 2729 Z-score: 2312.2 bits: 437.0 E(85289): 4.7e-122 Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:63-472) 10 20 30 pF1KE0 MVLKAEHTRSPSATLPSNVPSCRSLSSSED :::::::::::::::::::::::::::::: XP_011 TYSLSVSKISVNYLLDCIDAIEKAACSLKVMVLKAEHTRSPSATLPSNVPSCRSLSSSED 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE0 GPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPH 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE0 IQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKA 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE0 LLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSEPPEPGGEDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELE 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE0 EAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLK 280 290 300 310 320 330 280 290 300 310 320 330 pF1KE0 HNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFK 340 350 360 370 380 390 340 350 360 370 380 390 pF1KE0 FLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQE 400 410 420 430 440 450 400 410 pF1KE0 WVPSRCRLYSKDSGPPADGP :::::::::::::::::::: XP_011 WVPSRCRLYSKDSGPPADGP 460 470 >>XP_011529419 (OMIM: 300092) PREDICTED: testis-specific (413 aa) initn: 2706 init1: 2706 opt: 2706 Z-score: 2293.7 bits: 433.4 E(85289): 5.1e-121 Smith-Waterman score: 2706; 100.0% identity (100.0% similar) in 406 aa overlap (5-410:8-413) 10 20 30 40 50 pF1KE0 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILY ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQLLDHLAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 LSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 QQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 SRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 LESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITET 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 FKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE0 SSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP 370 380 390 400 410 >>XP_011529420 (OMIM: 300092) PREDICTED: testis-specific (413 aa) initn: 2706 init1: 2706 opt: 2706 Z-score: 2293.7 bits: 433.4 E(85289): 5.1e-121 Smith-Waterman score: 2706; 100.0% identity (100.0% similar) in 406 aa overlap (5-410:8-413) 10 20 30 40 50 pF1KE0 MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILY ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQLLDHLAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 LSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 QQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGGEDGPVNLPHASRPFILE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 SRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE0 LESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITET 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE0 FKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE0 SSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP 370 380 390 400 410 >>XP_011510886 (OMIM: 616242) PREDICTED: transmembrane a (463 aa) initn: 605 init1: 270 opt: 409 Z-score: 356.1 bits: 75.0 E(85289): 4.3e-13 Smith-Waterman score: 512; 30.5% identity (59.7% similar) in 407 aa overlap (51-383:47-451) 30 40 50 60 70 80 pF1KE0 SCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLV ....:: :.::... ...:: :.. ::::. XP_011 AVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLA 20 30 40 50 60 70 90 100 110 120 pF1KE0 SKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP----------- ..::..:. .:.:.::: ::... :: :....:.. :..:.:.:.. : XP_011 NSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMH 80 90 100 110 120 130 130 140 150 160 pF1KE0 --------------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGP ::.. .. :. .. . :..:.: : :. :. XP_011 QGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNI 140 150 160 170 180 190 170 180 190 pF1KE0 VNLPH---------ASRPFILESRFQSLQQ---------------GTCLETEDVA----- :: :.. . . : ::: . :. : .: XP_011 PNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASS 200 210 220 230 240 250 200 210 220 230 240 pF1KE0 QQQNLLLQKVKA------ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA .. : : .. .. :..: .. . :.::...:::. : .:....::::. : XP_011 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 260 270 280 290 300 310 250 260 270 280 290 300 pF1KE0 LMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQ .:::.: . . ::: :::..:: ::..:: :::::..: : :. ..::::.:. : XP_011 RLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQ 320 330 340 350 360 370 310 320 330 340 350 360 pF1KE0 Q---VTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTM : :.:::. :. .: ..: :... :.. .::::::::. : :...: : . XP_011 QQQQVVQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 380 390 400 410 420 430 370 380 390 400 410 pF1KE0 LMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :.:. . .. :..: :. XP_011 LFLVVFIAFLWKHWDALFSYVERFFSSPR 440 450 460 >>XP_011510885 (OMIM: 616242) PREDICTED: transmembrane a (463 aa) initn: 605 init1: 270 opt: 409 Z-score: 356.1 bits: 75.0 E(85289): 4.3e-13 Smith-Waterman score: 512; 30.5% identity (59.7% similar) in 407 aa overlap (51-383:47-451) 30 40 50 60 70 80 pF1KE0 SCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLV ....:: :.::... ...:: :.. ::::. XP_011 AVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLA 20 30 40 50 60 70 90 100 110 120 pF1KE0 SKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP----------- ..::..:. .:.:.::: ::... :: :....:.. :..:.:.:.. : XP_011 NSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMH 80 90 100 110 120 130 130 140 150 160 pF1KE0 --------------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGP ::.. .. :. .. . :..:.: : :. :. XP_011 QGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNI 140 150 160 170 180 190 170 180 190 pF1KE0 VNLPH---------ASRPFILESRFQSLQQ---------------GTCLETEDVA----- :: :.. . . : ::: . :. : .: XP_011 PNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASS 200 210 220 230 240 250 200 210 220 230 240 pF1KE0 QQQNLLLQKVKA------ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA .. : : .. .. :..: .. . :.::...:::. : .:....::::. : XP_011 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 260 270 280 290 300 310 250 260 270 280 290 300 pF1KE0 LMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQ .:::.: . . ::: :::..:: ::..:: :::::..: : :. ..::::.:. : XP_011 RLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQ 320 330 340 350 360 370 310 320 330 340 350 360 pF1KE0 Q---VTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTM : :.:::. :. .: ..: :... :.. .::::::::. : :...: : . XP_011 QQQQVVQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 380 390 400 410 420 430 370 380 390 400 410 pF1KE0 LMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :.:. . .. :..: :. XP_011 LFLVVFIAFLWKHWDALFSYVERFFSSPR 440 450 460 >>XP_016861429 (OMIM: 616242) PREDICTED: transmembrane a (463 aa) initn: 605 init1: 270 opt: 409 Z-score: 356.1 bits: 75.0 E(85289): 4.3e-13 Smith-Waterman score: 512; 30.5% identity (59.7% similar) in 407 aa overlap (51-383:47-451) 30 40 50 60 70 80 pF1KE0 SCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLV ....:: :.::... ...:: :.. ::::. XP_016 AVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLA 20 30 40 50 60 70 90 100 110 120 pF1KE0 SKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP----------- ..::..:. .:.:.::: ::... :: :....:.. :..:.:.:.. : XP_016 NSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMH 80 90 100 110 120 130 130 140 150 160 pF1KE0 --------------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGP ::.. .. :. .. . :..:.: : :. :. XP_016 QGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNI 140 150 160 170 180 190 170 180 190 pF1KE0 VNLPH---------ASRPFILESRFQSLQQ---------------GTCLETEDVA----- :: :.. . . : ::: . :. : .: XP_016 PNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASS 200 210 220 230 240 250 200 210 220 230 240 pF1KE0 QQQNLLLQKVKA------ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA .. : : .. .. :..: .. . :.::...:::. : .:....::::. : XP_016 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 260 270 280 290 300 310 250 260 270 280 290 300 pF1KE0 LMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQ .:::.: . . ::: :::..:: ::..:: :::::..: : :. ..::::.:. : XP_016 RLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQ 320 330 340 350 360 370 310 320 330 340 350 360 pF1KE0 Q---VTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTM : :.:::. :. .: ..: :... :.. .::::::::. : :...: : . XP_016 QQQQVVQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 380 390 400 410 420 430 370 380 390 400 410 pF1KE0 LMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :.:. . .. :..: :. XP_016 LFLVVFIAFLWKHWDALFSYVERFFSSPR 440 450 460 >>XP_016861430 (OMIM: 616242) PREDICTED: transmembrane a (463 aa) initn: 605 init1: 270 opt: 409 Z-score: 356.1 bits: 75.0 E(85289): 4.3e-13 Smith-Waterman score: 512; 30.5% identity (59.7% similar) in 407 aa overlap (51-383:47-451) 30 40 50 60 70 80 pF1KE0 SCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLV ....:: :.::... ...:: :.. ::::. XP_016 AVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLA 20 30 40 50 60 70 90 100 110 120 pF1KE0 SKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP----------- ..::..:. .:.:.::: ::... :: :....:.. :..:.:.:.. : XP_016 NSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMH 80 90 100 110 120 130 130 140 150 160 pF1KE0 --------------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGP ::.. .. :. .. . :..:.: : :. :. XP_016 QGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNI 140 150 160 170 180 190 170 180 190 pF1KE0 VNLPH---------ASRPFILESRFQSLQQ---------------GTCLETEDVA----- :: :.. . . : ::: . :. : .: XP_016 PNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASS 200 210 220 230 240 250 200 210 220 230 240 pF1KE0 QQQNLLLQKVKA------ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA .. : : .. .. :..: .. . :.::...:::. : .:....::::. : XP_016 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 260 270 280 290 300 310 250 260 270 280 290 300 pF1KE0 LMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQ .:::.: . . ::: :::..:: ::..:: :::::..: : :. ..::::.:. : XP_016 RLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQ 320 330 340 350 360 370 310 320 330 340 350 360 pF1KE0 Q---VTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTM : :.:::. :. .: ..: :... :.. .::::::::. : :...: : . XP_016 QQQQVVQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 380 390 400 410 420 430 370 380 390 400 410 pF1KE0 LMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :.:. . .. :..: :. XP_016 LFLVVFIAFLWKHWDALFSYVERFFSSPR 440 450 460 >>XP_006713616 (OMIM: 616242) PREDICTED: transmembrane a (470 aa) initn: 574 init1: 270 opt: 409 Z-score: 356.0 bits: 75.0 E(85289): 4.3e-13 Smith-Waterman score: 512; 30.5% identity (59.7% similar) in 407 aa overlap (51-383:54-458) 30 40 50 60 70 80 pF1KE0 SCRSLSSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLV ....:: :.::... ...:: :.. ::::. XP_006 AVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLA 30 40 50 60 70 80 90 100 110 120 pF1KE0 SKADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP----------- ..::..:. .:.:.::: ::... :: :....:.. :..:.:.:.. : XP_006 NSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMH 90 100 110 120 130 140 130 140 150 160 pF1KE0 --------------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGP ::.. .. :. .. . :..:.: : :. :. XP_006 QGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNI 150 160 170 180 190 200 170 180 190 pF1KE0 VNLPH---------ASRPFILESRFQSLQQ---------------GTCLETEDVA----- :: :.. . . : ::: . :. : .: XP_006 PNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASS 210 220 230 240 250 260 200 210 220 230 240 pF1KE0 QQQNLLLQKVKA------ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQA .. : : .. .. :..: .. . :.::...:::. : .:....::::. : XP_006 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 270 280 290 300 310 320 250 260 270 280 290 300 pF1KE0 LMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQ .:::.: . . ::: :::..:: ::..:: :::::..: : :. ..::::.:. : XP_006 RLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQ 330 340 350 360 370 380 310 320 330 340 350 360 pF1KE0 Q---VTQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTM : :.:::. :. .: ..: :... :.. .::::::::. : :...: : . XP_006 QQQQVVQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 390 400 410 420 430 440 370 380 390 400 410 pF1KE0 LMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP :.:. . .. :..: :. XP_006 LFLVVFIAFLWKHWDALFSYVERFFSSPR 450 460 470 410 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:40:09 2016 done: Thu Nov 3 21:40:11 2016 Total Scan time: 10.840 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]