FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0197, 119 aa 1>>>pF1KE0197 119 - 119 aa - 119 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0065+/-0.000296; mu= 13.5212+/- 0.019 mean_var=77.2840+/-14.637, 0's: 0 Z-trim(118.4): 42 B-trim: 177 in 1/53 Lambda= 0.145891 statistics sampled from 31194 (31236) to 31194 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.366), width: 16 Scan time: 4.780 The best scores are: opt bits E(85289) NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 782 172.8 1.2e-43 NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 592 132.7 1e-31 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 592 132.7 1.1e-31 NP_001171605 (OMIM: 600835,609423) stromal cell-de ( 140) 594 133.3 1.1e-31 NP_001264919 (OMIM: 600835,609423) stromal cell-de ( 103) 255 61.8 2.6e-10 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 164 42.6 0.00015 NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 158 41.5 0.00042 NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 153 40.4 0.00077 NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 152 40.1 0.0009 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 147 39.0 0.0017 NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 142 38.1 0.004 NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 140 37.6 0.0052 >>NP_001029058 (OMIM: 600835,609423) stromal cell-derive (119 aa) initn: 782 init1: 782 opt: 782 Z-score: 904.8 bits: 172.8 E(85289): 1.2e-43 Smith-Waterman score: 782; 100.0% identity (100.0% similar) in 119 aa overlap (1-119:1-119) 10 20 30 40 50 60 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQKRKN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQKRKN 70 80 90 100 110 >>NP_954637 (OMIM: 600835,609423) stromal cell-derived f (89 aa) initn: 592 init1: 592 opt: 592 Z-score: 690.3 bits: 132.7 E(85289): 1e-31 Smith-Waterman score: 592; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQKRKN ::::::::::::::::::::::::::::: NP_954 ARLKNNNRQVCIDPKLKWIQEYLEKALNK 70 80 >>NP_000600 (OMIM: 600835,609423) stromal cell-derived f (93 aa) initn: 592 init1: 592 opt: 592 Z-score: 690.0 bits: 132.7 E(85289): 1.1e-31 Smith-Waterman score: 592; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQKRKN ::::::::::::::::::::::::::::: NP_000 ARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM 70 80 90 >>NP_001171605 (OMIM: 600835,609423) stromal cell-derive (140 aa) initn: 627 init1: 591 opt: 594 Z-score: 690.0 bits: 133.3 E(85289): 1.1e-31 Smith-Waterman score: 594; 86.7% identity (90.5% similar) in 105 aa overlap (1-105:1-105) 10 20 30 40 50 60 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQKRKN ::::::::::::::::::::::::::::. .::. : . NP_001 ARLKNNNRQVCIDPKLKWIQEYLEKALNNLISAAPAGKRVIAGARALHPSPPRACPTARA 70 80 90 100 110 120 NP_001 LCEIRLWPPPEWSWPSPGDV 130 140 >>NP_001264919 (OMIM: 600835,609423) stromal cell-derive (103 aa) initn: 265 init1: 255 opt: 255 Z-score: 306.1 bits: 61.8 E(85289): 2.6e-10 Smith-Waterman score: 255; 100.0% identity (100.0% similar) in 38 aa overlap (1-38:1-38) 10 20 30 40 50 60 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV :::::::::::::::::::::::::::::::::::::: NP_001 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHYCTCLIRVSFHGATPLTQGSWV 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQKRKN NP_001 LYSLSCAGGETGLREPGPMVSPRVESHQEGRLGVPGPVNLGKA 70 80 90 100 >>NP_000575 (OMIM: 146930) interleukin-8 precursor [Homo (99 aa) initn: 138 init1: 95 opt: 164 Z-score: 202.8 bits: 42.6 E(85289): 0.00015 Smith-Waterman score: 164; 31.2% identity (69.8% similar) in 96 aa overlap (1-89:1-95) 10 20 30 40 50 pF1KE0 MNAKVVVVLV---LVLTALCLSDGKPVSLS-YRCPC-RFFESHVARANVKHLKILNT-PN :..:..:.:. :. .::: . : : . :: : . . . .:.:..... :. NP_000 MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 CA-LQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKA :: .:...: ...:..:.::: .:.:. .:: :.. NP_000 CANTEIIVKL-SDGRELCLDPKENWVQRVVEKFLKRAENS 70 80 90 pF1KE0 AQKRKN >>NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 precu (125 aa) initn: 146 init1: 52 opt: 158 Z-score: 194.7 bits: 41.5 E(85289): 0.00042 Smith-Waterman score: 158; 30.8% identity (62.5% similar) in 120 aa overlap (5-118:6-121) 10 20 30 40 50 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPC-RFFESHVARANVKHLKILN-TPNCA- :. .: ..: .: .: :: . :: : .. . ..: :: . .:.: NP_002 MKKSGVLFLLGIILLVLIGVQGTPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 LQIVARLKNNNRQVCIDPKLKWIQEYL---EKALNKGRREEKVGKKEKIGKKKRQKKRKA ..:.: :::. :.:..: ..: . :: ... ....: :::.. ::: : ::. NP_002 IEIIATLKNGV-QTCLNPDSADVKELIKKWEKQVSQ-KKKQKNGKKHQ--KKKVLKVRKS 70 80 90 100 110 pF1KE0 AQKRKN ..:. NP_002 QRSRQKKTT 120 >>NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 precu (107 aa) initn: 133 init1: 103 opt: 153 Z-score: 189.9 bits: 40.4 E(85289): 0.00077 Smith-Waterman score: 153; 29.2% identity (62.9% similar) in 89 aa overlap (4-90:17-104) 10 20 30 40 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHL .:...:.:...: . : : :: : . . :.. . NP_002 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 KILNT-PNCA-LQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKK .. . :.:: ...: :::. ...:..: .:. .:: :::: NP_002 NVRSPGPHCAQTEVIATLKNG-KKACLNPASPMVQKIIEKILNKGSTN 70 80 90 100 110 pF1KE0 KRQKKRKAAQKRKN >>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa) initn: 93 init1: 75 opt: 152 Z-score: 188.7 bits: 40.1 E(85289): 0.0009 Smith-Waterman score: 152; 26.7% identity (65.6% similar) in 90 aa overlap (4-91:17-105) 10 20 30 40 pF1KE0 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHL .:...:.:...: . : :.. :: : . . :.. . NP_002 MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 KILNT-PNCA-LQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKK :. . :.:: ...: :::. ...:..: ... .:: :..:. NP_002 KVKSPGPHCAQTEVIATLKNG-QKACLNPASPMVKKIIEKMLKNGKSN 70 80 90 100 110 pF1KE0 KRQKKRKAAQKRKN >>NP_002976 (OMIM: 187011) C-C motif chemokine 5 isoform (91 aa) initn: 116 init1: 90 opt: 147 Z-score: 184.0 bits: 39.0 E(85289): 0.0017 Smith-Waterman score: 147; 33.3% identity (66.7% similar) in 81 aa overlap (7-83:8-85) 10 20 30 40 50 pF1KE0 MNAKVVVVLVLVLTALCL-SDGKPVSLSYRCPCRFFESHVARANVK-HLK--ILNTPNC ....:. :::: ....: : : :: : ...:: . :.: . .. .: NP_002 MKVSAAALAVILIATALCAPASASPYS-SDTTPCCF--AYIARPLPRAHIKEYFYTSGKC 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 ALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKGRREEKVGKKEKIGKKKRQKKRKAAQ . :. . .::::: .:. ::..::. NP_002 SNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS 60 70 80 90 119 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:21:06 2016 done: Sat Nov 5 01:21:07 2016 Total Scan time: 4.780 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]