FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0200, 454 aa 1>>>pF1KE0200 454 - 454 aa - 454 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4196+/-0.000779; mu= 5.2696+/- 0.048 mean_var=183.7783+/-36.515, 0's: 0 Z-trim(115.1): 20 B-trim: 37 in 1/53 Lambda= 0.094608 statistics sampled from 15603 (15618) to 15603 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.48), width: 16 Scan time: 3.930 The best scores are: opt bits E(32554) CCDS6359.2 MYC gene_id:4609|Hs108|chr8 ( 454) 3030 425.4 6e-119 CCDS1687.1 MYCN gene_id:4613|Hs108|chr2 ( 464) 468 75.7 1.1e-13 >>CCDS6359.2 MYC gene_id:4609|Hs108|chr8 (454 aa) initn: 3030 init1: 3030 opt: 3030 Z-score: 2248.9 bits: 425.4 E(32554): 6e-119 Smith-Waterman score: 3030; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KE0 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 STESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 STESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 RSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILS 370 380 390 400 410 420 430 440 450 pF1KE0 VQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA :::::::::::::::::::::::::::::::::: CCDS63 VQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA 430 440 450 >>CCDS1687.1 MYCN gene_id:4613|Hs108|chr2 (464 aa) initn: 791 init1: 360 opt: 468 Z-score: 358.9 bits: 75.7 E(32554): 1.1e-13 Smith-Waterman score: 876; 40.4% identity (61.7% similar) in 488 aa overlap (14-453:7-464) 10 20 30 40 50 60 pF1KE0 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP .::: . .: ::..::.:: :: ::.. :: .: ::. CCDS16 MPSCSTSTMPGMIC---KNPDLEFDSLQPCFYPDEDD-FYFGGPDST--PPG- 10 20 30 40 70 80 90 100 110 pF1KE0 SEDIWKKFELLPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMV ::::::::::::::::::: . : ::. :: . : .:. : : :.. . CCDS16 -EDIWKKFELLPTPPLSPSRGFAEHSSEPPSW--VTEMLL--ENELWG---SPAEEDAFG 50 60 70 80 90 120 130 140 150 160 pF1KE0 TELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------AS ::: : : .:.:::::::::: :: ::::: :. CCDS16 LGGLGGLTPN------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAG 100 110 120 130 140 170 180 190 200 210 220 pF1KE0 YQAARKDSGSPNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SP : .:. .:: :::. . ... .:. :.::.::.::::.:.: .: CCDS16 STAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAP 150 160 170 180 190 200 230 240 250 260 pF1KE0 KSCASQDSSAFSPS--SDSLLSSTESSPQ-GSPEP------------LVLHEETPPTTSS : .. : .:. : . ... ..: . :.: : : . :. CCDS16 VPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSD 210 220 230 240 250 260 270 280 290 300 310 pF1KE0 DSEEEQEDEEE-IDVVSVEKRQAPGKRSESGS------P--SAGGHSKPPHSPLVLKRCH : ..:.::::: ::::.::::.. .. . . : .: : .. : :.:::: CCDS16 DEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELILKRCL 270 280 290 300 310 320 320 330 340 350 360 370 pF1KE0 VSTHQHNYAAP-PSTR-KDYPAAKRVKLD-SVRVLRQISNNR-KCTSPRSSDTEENVKRR .::::::: : .. .: : :..: . : : :... . : :::.::.:.. .:: CCDS16 PIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRR 330 340 350 360 370 380 380 390 400 410 420 430 pF1KE0 THNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEE .::.:::::::.:. ::..:::..::: .:::: ::::::::: :. :.::::..:. :. CCDS16 NHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEK 390 400 410 420 430 440 440 450 pF1KE0 DLLRKRREQLKHKLEQLRNSCA . :. :..:: .:.:. : .: CCDS16 EKLQARQQQLLKKIEHAR-TC 450 460 454 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:57:13 2016 done: Sat Nov 5 01:57:14 2016 Total Scan time: 3.930 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]