FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0202, 268 aa 1>>>pF1KE0202 268 - 268 aa - 268 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1422+/-0.00114; mu= -5.2301+/- 0.069 mean_var=374.9478+/-75.692, 0's: 0 Z-trim(113.0): 54 B-trim: 0 in 0/52 Lambda= 0.066235 statistics sampled from 13617 (13649) to 13617 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.419), width: 16 Scan time: 2.830 The best scores are: opt bits E(32554) CCDS946.1 ANP32E gene_id:81611|Hs108|chr1 ( 268) 1735 179.1 2.9e-45 CCDS44215.1 ANP32E gene_id:81611|Hs108|chr1 ( 220) 1425 149.4 2.1e-36 CCDS44214.1 ANP32E gene_id:81611|Hs108|chr1 ( 227) 1088 117.2 1e-26 CCDS45292.1 ANP32A gene_id:8125|Hs108|chr15 ( 249) 906 99.8 1.9e-21 CCDS6732.1 ANP32B gene_id:10541|Hs108|chr9 ( 251) 885 97.8 7.7e-21 CCDS60245.1 ANP32E gene_id:81611|Hs108|chr1 ( 165) 694 79.4 1.8e-15 CCDS31788.1 ANP32D gene_id:23519|Hs108|chr12 ( 131) 544 64.9 3.2e-11 >>CCDS946.1 ANP32E gene_id:81611|Hs108|chr1 (268 aa) initn: 1735 init1: 1735 opt: 1735 Z-score: 926.2 bits: 179.1 E(32554): 2.9e-45 Smith-Waterman score: 1735; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268) 10 20 30 40 50 60 pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 190 200 210 220 230 240 250 260 pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD :::::::::::::::::::::::::::: CCDS94 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 250 260 >>CCDS44215.1 ANP32E gene_id:81611|Hs108|chr1 (220 aa) initn: 1425 init1: 1425 opt: 1425 Z-score: 767.1 bits: 149.4 E(32554): 2.1e-36 Smith-Waterman score: 1425; 100.0% identity (100.0% similar) in 220 aa overlap (49-268:1-220) 20 30 40 50 60 70 pF1KE0 VTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISG :::::::::::::::::::::::::::::: CCDS44 MANVELSSLARLPSLNKLRKLELSDNIISG 10 20 30 80 90 100 110 120 130 pF1KE0 GLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFEL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE0 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE0 DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD 160 170 180 190 200 210 260 pF1KE0 AEDDGEEEDD :::::::::: CCDS44 AEDDGEEEDD 220 >>CCDS44214.1 ANP32E gene_id:81611|Hs108|chr1 (227 aa) initn: 1056 init1: 1056 opt: 1088 Z-score: 592.9 bits: 117.2 E(32554): 1e-26 Smith-Waterman score: 1392; 84.7% identity (84.7% similar) in 268 aa overlap (1-268:1-227) 10 20 30 40 50 60 pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL :::::::: ::::::::::: CCDS44 PSLNKLRK-----------------------------------------QNLKNLKSLDL 70 130 140 150 160 170 180 pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 140 150 160 170 180 190 250 260 pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD :::::::::::::::::::::::::::: CCDS44 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 200 210 220 >>CCDS45292.1 ANP32A gene_id:8125|Hs108|chr15 (249 aa) initn: 1132 init1: 839 opt: 906 Z-score: 498.5 bits: 99.8 E(32554): 1.9e-21 Smith-Waterman score: 958; 59.2% identity (79.0% similar) in 267 aa overlap (1-267:1-249) 10 20 30 40 50 60 pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL ::: ..:.::::::.: .: :::::: .:..:::.: :.:::::: :: :.:.: : CCDS45 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL :.::::.::::::: .:::::::::::::::.:::::::::::::.: :..:.::::::: CCDS45 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP ::::.:::.::::..:.:: :.:::::.:..:.:::::. : .: :::::.:.: CCDS45 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE : . :.::.:..:.: :.:: .: : :.: : . :..::::.. : :: CCDS45 DEDAQVVEDEEDEDEEEEGEEEDVSGEEE---EDEEGYN---DGEVDDEEDEE---ELGE 180 190 200 210 220 230 250 260 pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD :: ::.::::. ::.::..: CCDS45 EE--------RGQKRKREPEDEGEDDD 240 >>CCDS6732.1 ANP32B gene_id:10541|Hs108|chr9 (251 aa) initn: 1055 init1: 879 opt: 885 Z-score: 487.6 bits: 97.8 E(32554): 7.7e-21 Smith-Waterman score: 949; 59.0% identity (79.9% similar) in 268 aa overlap (1-266:1-251) 10 20 30 40 50 60 pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL :.::..:.::::::.: : ::::::: .:.::::. : .:::::. :: : :.. : CCDS67 MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL :.: ::.:::::.: : :::..:::: ::::.:::::::.::.::.: :..:. :::::: CCDS67 PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEE-DDEDGDEDDEE-EEENEA ::::.:::.:::::.:.:: :.:::::.:.::.:::::. : : : .:.::: :.:.. CCDS67 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 GPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEE .: :::: .::.::::: . :: .:..: ::: :: ::::.:. CCDS67 DDEDG--EEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGL---------DEEDEDE---- 190 200 210 220 240 250 260 pF1KE0 GEEEEEEEEGGLRGEKRKRDAEDDGEEEDD .:.::::::: .::::::...:.::.. CCDS67 -DEDEEEEEGG-KGEKRKRETDDEGEDD 230 240 250 >>CCDS60245.1 ANP32E gene_id:81611|Hs108|chr1 (165 aa) initn: 711 init1: 694 opt: 694 Z-score: 391.1 bits: 79.4 E(32554): 1.8e-15 Smith-Waterman score: 694; 95.7% identity (98.3% similar) in 116 aa overlap (1-116:1-116) 10 20 30 40 50 60 pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL :::::::::::::::::::::::::::::::::::::::::::::::::. .: .: CCDS60 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALMAMKMMKRKRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP CCDS60 MKLVHRKDMRKRRRKRKRRMRMRMKMKMKQVQSWEREKRKWASHT 130 140 150 160 >>CCDS31788.1 ANP32D gene_id:23519|Hs108|chr12 (131 aa) initn: 544 init1: 544 opt: 544 Z-score: 314.9 bits: 64.9 E(32554): 3.2e-11 Smith-Waterman score: 544; 65.6% identity (85.5% similar) in 131 aa overlap (1-131:1-131) 10 20 30 40 50 60 pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL ::: : :.::::::.: .: :: ::: .:..:::.: :.:::.:. :. :.:.: : CCDS31 MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL :.::::.:::::.: : :::::::::::: .:::::::::::::.: :..:.::.:::: CCDS31 PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP :.::.:::..: CCDS31 FTCEVTNLNNY 130 268 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:29:54 2016 done: Thu Nov 3 21:29:54 2016 Total Scan time: 2.830 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]