FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0203, 301 aa 1>>>pF1KE0203 301 - 301 aa - 301 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2731+/-0.000299; mu= 9.0849+/- 0.019 mean_var=138.9956+/-27.862, 0's: 0 Z-trim(121.4): 8 B-trim: 0 in 0/54 Lambda= 0.108786 statistics sampled from 38065 (38073) to 38065 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.446), width: 16 Scan time: 5.950 The best scores are: opt bits E(85289) NP_060328 (OMIM: 610716) TIMELESS-interacting prot ( 301) 1996 323.8 2.6e-88 XP_006720657 (OMIM: 610716) PREDICTED: TIMELESS-in ( 301) 1983 321.7 1.1e-87 XP_016877879 (OMIM: 610716) PREDICTED: TIMELESS-in ( 301) 1983 321.7 1.1e-87 XP_005254578 (OMIM: 610716) PREDICTED: TIMELESS-in ( 301) 1983 321.7 1.1e-87 XP_011520045 (OMIM: 610716) PREDICTED: TIMELESS-in ( 301) 1983 321.7 1.1e-87 XP_005254579 (OMIM: 610716) PREDICTED: TIMELESS-in ( 301) 1983 321.7 1.1e-87 NP_001276915 (OMIM: 610716) TIMELESS-interacting p ( 200) 1291 213.0 3.9e-55 XP_016877880 (OMIM: 610716) PREDICTED: TIMELESS-in ( 200) 1291 213.0 3.9e-55 >>NP_060328 (OMIM: 610716) TIMELESS-interacting protein (301 aa) initn: 1996 init1: 1996 opt: 1996 Z-score: 1706.4 bits: 323.8 E(85289): 2.6e-88 Smith-Waterman score: 1996; 100.0% identity (100.0% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KE0 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 250 260 270 280 290 300 pF1KE0 R : NP_060 R >>XP_006720657 (OMIM: 610716) PREDICTED: TIMELESS-intera (301 aa) initn: 1983 init1: 1983 opt: 1983 Z-score: 1695.4 bits: 321.7 E(85289): 1.1e-87 Smith-Waterman score: 1983; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KE0 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_006 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVRVPPKRTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 250 260 270 280 290 300 pF1KE0 R : XP_006 R >>XP_016877879 (OMIM: 610716) PREDICTED: TIMELESS-intera (301 aa) initn: 1983 init1: 1983 opt: 1983 Z-score: 1695.4 bits: 321.7 E(85289): 1.1e-87 Smith-Waterman score: 1983; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KE0 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_016 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVRVPPKRTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 250 260 270 280 290 300 pF1KE0 R : XP_016 R >>XP_005254578 (OMIM: 610716) PREDICTED: TIMELESS-intera (301 aa) initn: 1983 init1: 1983 opt: 1983 Z-score: 1695.4 bits: 321.7 E(85289): 1.1e-87 Smith-Waterman score: 1983; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KE0 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_005 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVRVPPKRTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 250 260 270 280 290 300 pF1KE0 R : XP_005 R >>XP_011520045 (OMIM: 610716) PREDICTED: TIMELESS-intera (301 aa) initn: 1983 init1: 1983 opt: 1983 Z-score: 1695.4 bits: 321.7 E(85289): 1.1e-87 Smith-Waterman score: 1983; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KE0 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_011 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVRVPPKRTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 250 260 270 280 290 300 pF1KE0 R : XP_011 R >>XP_005254579 (OMIM: 610716) PREDICTED: TIMELESS-intera (301 aa) initn: 1983 init1: 1983 opt: 1983 Z-score: 1695.4 bits: 321.7 E(85289): 1.1e-87 Smith-Waterman score: 1983; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KE0 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_005 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVRVPPKRTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 250 260 270 280 290 300 pF1KE0 R : XP_005 R >>NP_001276915 (OMIM: 610716) TIMELESS-interacting prote (200 aa) initn: 1291 init1: 1291 opt: 1291 Z-score: 1110.9 bits: 213.0 E(85289): 3.9e-55 Smith-Waterman score: 1291; 100.0% identity (100.0% similar) in 200 aa overlap (102-301:1-200) 80 90 100 110 120 130 pF1KE0 LISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQFEDFIDRVEYLG :::::::::::::::::::::::::::::: NP_001 MLIRHMEHWAHRLFPKLQFEDFIDRVEYLG 10 20 30 140 150 160 170 180 190 pF1KE0 SKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASEL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 SRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEE 100 110 120 130 140 150 260 270 280 290 300 pF1KE0 SNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEAR :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEAR 160 170 180 190 200 >>XP_016877880 (OMIM: 610716) PREDICTED: TIMELESS-intera (200 aa) initn: 1291 init1: 1291 opt: 1291 Z-score: 1110.9 bits: 213.0 E(85289): 3.9e-55 Smith-Waterman score: 1291; 100.0% identity (100.0% similar) in 200 aa overlap (102-301:1-200) 80 90 100 110 120 130 pF1KE0 LISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQFEDFIDRVEYLG :::::::::::::::::::::::::::::: XP_016 MLIRHMEHWAHRLFPKLQFEDFIDRVEYLG 10 20 30 140 150 160 170 180 190 pF1KE0 SKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASEL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 SRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEE 100 110 120 130 140 150 260 270 280 290 300 pF1KE0 SNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEAR :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEAR 160 170 180 190 200 301 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:26:08 2016 done: Thu Nov 3 21:26:09 2016 Total Scan time: 5.950 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]