FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0206, 226 aa 1>>>pF1KE0206 226 - 226 aa - 226 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8721+/-0.000686; mu= 18.0037+/- 0.042 mean_var=85.8476+/-17.076, 0's: 0 Z-trim(111.8): 95 B-trim: 0 in 0/51 Lambda= 0.138424 statistics sampled from 12569 (12679) to 12569 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.389), width: 16 Scan time: 1.870 The best scores are: opt bits E(32554) CCDS34713.1 MYL10 gene_id:93408|Hs108|chr7 ( 226) 1497 307.9 3.4e-84 CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 ( 166) 763 161.2 3.7e-40 CCDS10677.1 MYLPF gene_id:29895|Hs108|chr16 ( 169) 695 147.6 4.5e-36 CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 ( 173) 606 129.9 1e-30 CCDS5478.1 MYL7 gene_id:58498|Hs108|chr7 ( 175) 591 126.9 8.3e-30 CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 ( 172) 502 109.1 1.8e-24 CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 ( 171) 492 107.1 7.3e-24 CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 ( 177) 492 107.1 7.5e-24 CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 ( 172) 485 105.7 1.9e-23 >>CCDS34713.1 MYL10 gene_id:93408|Hs108|chr7 (226 aa) initn: 1497 init1: 1497 opt: 1497 Z-score: 1625.1 bits: 307.9 E(32554): 3.4e-84 Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK 130 140 150 160 170 180 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD :::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD 190 200 210 220 >>CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 (166 aa) initn: 804 init1: 761 opt: 763 Z-score: 834.5 bits: 161.2 E(32554): 3.7e-40 Smith-Waterman score: 829; 67.0% identity (77.5% similar) in 200 aa overlap (27-226:2-166) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA ::..:.::: : :.:::::::.:.::::::: CCDS31 MAPKKAKKRA-GGANSNVFSMFEQTQIQEFKE--- 10 20 30 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN :::::::::::::::.:::::::::::.: CCDS31 -------------------------------AFTIMDQNRDGFIDKNDLRDTFAALGRVN 40 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK :::::.. :.::::::::::::::::::::::.:::::::.:::::: :::: .::: .. CCDS31 VKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVR 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD : : :::.:::.::: :::::::::: :::::.:: ..:::::::: CCDS31 EMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD 130 140 150 160 >>CCDS10677.1 MYLPF gene_id:29895|Hs108|chr16 (169 aa) initn: 717 init1: 695 opt: 695 Z-score: 761.0 bits: 147.6 E(32554): 4.5e-36 Smith-Waterman score: 756; 60.5% identity (75.0% similar) in 200 aa overlap (27-226:2-167) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA ::.::..:. .::.:::::::.::::::: CCDS10 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKE--- 10 20 30 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN :::..::::::.::::::::::::.::.: CCDS10 -------------------------------AFTVIDQNRDGIIDKEDLRDTFAAMGRLN 40 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK ::::::.::.::: ::::::::::::::::::.:::..: ::::.: :::: .: .. CCDS10 VKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFLE 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD : : :: ::::.::.:.:.::::::: ::.::.:.:::::::. :: CCDS10 ELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAKDQE 130 140 150 160 >>CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 (173 aa) initn: 721 init1: 604 opt: 606 Z-score: 664.9 bits: 129.9 E(32554): 1e-30 Smith-Waterman score: 638; 53.7% identity (70.2% similar) in 205 aa overlap (27-226:2-172) 10 20 30 40 50 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGT-----ASSNVFSMFDQSQIQEF : :...:. :. ::::::: :.:.::::: CCDS43 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEF 10 20 30 60 70 80 90 100 110 pF1KE0 KESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAA :: :::.::::::::::::::.::.:. CCDS43 KE----------------------------------AFTLMDQNRDGFIDKEDLKDTYAS 40 50 60 120 130 140 150 160 170 pF1KE0 LGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVK ::. :::..::.::.::: ::::::.::..:::::.::: :::::.:::..: .::: .. CCDS43 LGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKIN 70 80 90 100 110 120 180 190 200 210 220 pF1KE0 ADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD . ::. ::.:::... ::: ::: :: :::::. : :::::::::. CCDS43 KEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE 130 140 150 160 170 >>CCDS5478.1 MYL7 gene_id:58498|Hs108|chr7 (175 aa) initn: 719 init1: 589 opt: 591 Z-score: 648.6 bits: 126.9 E(32554): 8.3e-30 Smith-Waterman score: 623; 51.2% identity (70.4% similar) in 203 aa overlap (24-226:7-174) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA : .. : :.:. .::::::::.:.::::::: CCDS54 MASRKAGTRGKVAATKQAQ-RGSSNVFSMFEQAQIQEFKE--- 10 20 30 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN ::. .::::::.: : :::.:.. ::... CCDS54 -------------------------------AFSCIDQNRDGIICKADLRETYSQLGKVS 40 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK : .:::.::..:. ::::::::::.:::::.::::::.:: ::..:: ::: :. : .: CCDS54 VPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFK 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD . :.::::.:: ::.:::: : :. ::.::..:::.::::.::. CCDS54 QLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 130 140 150 160 170 >>CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 (172 aa) initn: 495 init1: 369 opt: 502 Z-score: 552.7 bits: 109.1 E(32554): 1.8e-24 Smith-Waterman score: 543; 46.5% identity (67.3% similar) in 202 aa overlap (26-226:5-171) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA .: .. :. :.::::.:::::::::::: CCDS13 MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKE--- 10 20 30 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN ::...:::::::::::::.: .:.::. : CCDS13 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N 40 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK .: ::.:..:::::::::.:::::::::.:::::..: .:: :: :..::.. : .. CCDS13 PTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLR 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD : : :..:::..::: .:. : : ::..: .. .. :: ..:: CCDS13 ELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 (171 aa) initn: 485 init1: 359 opt: 492 Z-score: 541.9 bits: 107.1 E(32554): 7.3e-24 Smith-Waterman score: 532; 46.5% identity (67.7% similar) in 198 aa overlap (30-226:9-170) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA ...:: . :.::::.:::::::::::: CCDS11 MSSKRTKTKTKKRPQ-RATSNVFAMFDQSQIQEFKE--- 10 20 30 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN ::...:::::::::::::.: .:.::. : CCDS11 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N 40 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK .: :.::..:::::::::.:::::::::.:::::..: .:: :: :. : .. : .. CCDS11 PTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD : : :..:::..::: ... : : ::..: .. .. :: ..:: CCDS11 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 (177 aa) initn: 485 init1: 359 opt: 492 Z-score: 541.7 bits: 107.1 E(32554): 7.5e-24 Smith-Waterman score: 532; 46.5% identity (67.7% similar) in 198 aa overlap (30-226:15-176) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA ...:: . :.::::.:::::::::::: CCDS77 MDLTTTMSSKRTKTKTKKRPQ-RATSNVFAMFDQSQIQEFKE--- 10 20 30 40 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN ::...:::::::::::::.: .:.::. : CCDS77 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK .: :.::..:::::::::.:::::::::.:::::..: .:: :: :. : .. : .. CCDS77 PTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD : : :..:::..::: ... : : ::..: .. .. :: ..:: CCDS77 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 130 140 150 160 170 >>CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 (172 aa) initn: 476 init1: 350 opt: 485 Z-score: 534.3 bits: 105.7 E(32554): 1.9e-23 Smith-Waterman score: 528; 45.0% identity (65.8% similar) in 202 aa overlap (26-226:5-171) 10 20 30 40 50 60 pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA .: .. :. :.::::.:::::::::::: CCDS11 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKE--- 10 20 30 70 80 90 100 110 120 pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN ::...:::::::::::::.: .:.::. : CCDS11 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N 40 50 60 130 140 150 160 170 180 pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK . :.::..:::::::::.:::::::::.:::::..: .:: :: :. : .. : .. CCDS11 PTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 70 80 90 100 110 120 190 200 210 220 pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD : : :..:::..::: ... : : ::..: .. .. :: ..:: CCDS11 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 130 140 150 160 170 226 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:18:55 2016 done: Thu Nov 3 21:18:56 2016 Total Scan time: 1.870 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]