Result of FASTA (omim) for
pF1KE0206
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0206, 226 aa
1>>>pF1KE0206 226 - 226 aa - 226 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3862+/-0.00029; mu= 21.1006+/- 0.018
mean_var=92.6963+/-19.311, 0's: 0 Z-trim(119.2): 173 B-trim: 810 in 1/52
Lambda= 0.133212
statistics sampled from 32706 (32949) to 32706 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.386), width: 16
Scan time: 6.700
The best scores are: opt bits E(85289)
NP_000423 (OMIM: 160781,608758) myosin regulatory ( 166) 763 155.7 4.4e-38
NP_002468 (OMIM: 160782) myosin light chain 5 [Hom ( 173) 606 125.5 5.5e-29
XP_016863735 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 606 125.5 5.5e-29
XP_016863734 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 606 125.5 5.5e-29
XP_006713949 (OMIM: 160782) PREDICTED: myosin ligh ( 328) 606 125.9 7.9e-29
NP_067046 (OMIM: 613993) myosin regulatory light c ( 175) 591 122.6 4e-28
XP_016863736 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 584 121.1 8.7e-28
XP_016863737 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 584 121.1 8.7e-28
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 502 105.5 5.6e-23
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 485 102.3 5.4e-22
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 485 102.3 5.4e-22
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 485 102.3 5.4e-22
XP_011513765 (OMIM: 613993) PREDICTED: myosin regu ( 231) 462 98.0 1.4e-20
XP_016867968 (OMIM: 613993) PREDICTED: myosin regu ( 99) 443 93.9 1.1e-19
XP_011513766 (OMIM: 613993) PREDICTED: myosin regu ( 208) 446 94.9 1.1e-19
XP_005249874 (OMIM: 613993) PREDICTED: myosin regu ( 155) 397 85.3 6.3e-17
XP_016867967 (OMIM: 613993) PREDICTED: myosin regu ( 132) 381 82.1 4.8e-16
XP_011513767 (OMIM: 613993) PREDICTED: myosin regu ( 163) 381 82.2 5.5e-16
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 259 58.7 5.9e-09
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 259 58.7 5.9e-09
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 259 58.7 5.9e-09
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 259 58.7 5.9e-09
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 259 58.8 6e-09
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 259 58.9 7e-09
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 256 58.2 8.9e-09
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 211 49.4 3e-06
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 211 49.4 3e-06
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 211 49.4 3e-06
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 211 49.4 3e-06
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 211 49.4 3e-06
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 211 49.4 3e-06
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 211 49.4 3e-06
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 198 47.1 2.2e-05
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 189 45.4 7.1e-05
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 186 44.8 0.00011
XP_016871787 (OMIM: 614215,614266,616867) PREDICTE ( 320) 184 44.8 0.0002
XP_016871786 (OMIM: 614215,614266,616867) PREDICTE ( 320) 184 44.8 0.0002
XP_016871784 (OMIM: 614215,614266,616867) PREDICTE ( 332) 184 44.8 0.00021
XP_011538143 (OMIM: 614215,614266,616867) PREDICTE ( 360) 184 44.9 0.00022
XP_011538144 (OMIM: 614215,614266,616867) PREDICTE ( 360) 184 44.9 0.00022
XP_016871780 (OMIM: 614215,614266,616867) PREDICTE ( 372) 184 44.9 0.00022
XP_016871781 (OMIM: 614215,614266,616867) PREDICTE ( 372) 184 44.9 0.00022
NP_001185728 (OMIM: 614215,614266,616867) activati ( 400) 184 44.9 0.00023
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 180 43.6 0.00023
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 180 43.7 0.00025
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191) 180 43.7 0.00026
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 180 43.7 0.00026
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 177 43.0 0.00033
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 166 40.9 0.0014
NP_001311126 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 172 43.1 0.0018
>>NP_000423 (OMIM: 160781,608758) myosin regulatory ligh (166 aa)
initn: 804 init1: 761 opt: 763 Z-score: 804.7 bits: 155.7 E(85289): 4.4e-38
Smith-Waterman score: 829; 67.0% identity (77.5% similar) in 200 aa overlap (27-226:2-166)
10 20 30 40 50 60
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA
::..:.::: : :.:::::::.:.:::::::
NP_000 MAPKKAKKRA-GGANSNVFSMFEQTQIQEFKE---
10 20 30
70 80 90 100 110 120
pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN
:::::::::::::::.:::::::::::.:
NP_000 -------------------------------AFTIMDQNRDGFIDKNDLRDTFAALGRVN
40 50 60
130 140 150 160 170 180
pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK
:::::.. :.::::::::::::::::::::::.:::::::.:::::: :::: .::: ..
NP_000 VKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVR
70 80 90 100 110 120
190 200 210 220
pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
: : :::.:::.::: :::::::::: :::::.:: ..::::::::
NP_000 EMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
130 140 150 160
>>NP_002468 (OMIM: 160782) myosin light chain 5 [Homo sa (173 aa)
initn: 721 init1: 604 opt: 606 Z-score: 641.4 bits: 125.5 E(85289): 5.5e-29
Smith-Waterman score: 638; 53.7% identity (70.2% similar) in 205 aa overlap (27-226:2-172)
10 20 30 40 50
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGT-----ASSNVFSMFDQSQIQEF
: :...:. :. ::::::: :.:.:::::
NP_002 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEF
10 20 30
60 70 80 90 100 110
pF1KE0 KESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAA
:: :::.::::::::::::::.::.:.
NP_002 KE----------------------------------AFTLMDQNRDGFIDKEDLKDTYAS
40 50 60
120 130 140 150 160 170
pF1KE0 LGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVK
::. :::..::.::.::: ::::::.::..:::::.::: :::::.:::..: .::: ..
NP_002 LGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKIN
70 80 90 100 110 120
180 190 200 210 220
pF1KE0 ADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
. ::. ::.:::... ::: ::: :: :::::. : :::::::::.
NP_002 KEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
130 140 150 160 170
>>XP_016863735 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 721 init1: 604 opt: 606 Z-score: 641.4 bits: 125.5 E(85289): 5.5e-29
Smith-Waterman score: 638; 53.7% identity (70.2% similar) in 205 aa overlap (27-226:2-172)
10 20 30 40 50
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGT-----ASSNVFSMFDQSQIQEF
: :...:. :. ::::::: :.:.:::::
XP_016 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEF
10 20 30
60 70 80 90 100 110
pF1KE0 KESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAA
:: :::.::::::::::::::.::.:.
XP_016 KE----------------------------------AFTLMDQNRDGFIDKEDLKDTYAS
40 50 60
120 130 140 150 160 170
pF1KE0 LGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVK
::. :::..::.::.::: ::::::.::..:::::.::: :::::.:::..: .::: ..
XP_016 LGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKIN
70 80 90 100 110 120
180 190 200 210 220
pF1KE0 ADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
. ::. ::.:::... ::: ::: :: :::::. : :::::::::.
XP_016 KEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
130 140 150 160 170
>>XP_016863734 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 721 init1: 604 opt: 606 Z-score: 641.4 bits: 125.5 E(85289): 5.5e-29
Smith-Waterman score: 638; 53.7% identity (70.2% similar) in 205 aa overlap (27-226:2-172)
10 20 30 40 50
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGT-----ASSNVFSMFDQSQIQEF
: :...:. :. ::::::: :.:.:::::
XP_016 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEF
10 20 30
60 70 80 90 100 110
pF1KE0 KESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAA
:: :::.::::::::::::::.::.:.
XP_016 KE----------------------------------AFTLMDQNRDGFIDKEDLKDTYAS
40 50 60
120 130 140 150 160 170
pF1KE0 LGRINVKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVK
::. :::..::.::.::: ::::::.::..:::::.::: :::::.:::..: .::: ..
XP_016 LGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKIN
70 80 90 100 110 120
180 190 200 210 220
pF1KE0 ADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
. ::. ::.:::... ::: ::: :: :::::. : :::::::::.
XP_016 KEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
130 140 150 160 170
>>XP_006713949 (OMIM: 160782) PREDICTED: myosin light ch (328 aa)
initn: 748 init1: 604 opt: 606 Z-score: 638.5 bits: 125.9 E(85289): 7.9e-29
Smith-Waterman score: 656; 51.9% identity (66.5% similar) in 233 aa overlap (7-226:129-327)
10 20 30
pF1KE0 MLLRLVSNSWPQVILPP-RPPKVLGLQAPRR----A
: ::: : : : ..:. : :: .
XP_006 AGSAPSGRGVSFPRRAGGPLFPRAAAEAPPSASWPCVHTPDCGPGRTLSSCAERRRPEAS
100 110 120 130 140 150
40 50 60 70 80
pF1KE0 RK--RAEG------TASSNVFSMFDQSQIQEFKESLALSPRLERNGMISAHCNLCLTGSS
:: . :: ::::::: :.:.:::::::
XP_006 RKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKE--------------------------
160 170 180 190
90 100 110 120 130 140
pF1KE0 NSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPINFTVFL
:::.::::::::::::::.::.:.::. :::..::.::.::: ::::::.::
XP_006 --------AFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFTMFL
200 210 220 230 240
150 160 170 180 190 200
pF1KE0 TMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIKEKLMTQADRFSEEEVKQMFAAFP
..:::::.::: :::::.:::..: .::: .. . ::. ::.:::... ::: :::
XP_006 NLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFAS
250 260 270 280 290 300
210 220
pF1KE0 PDVCGNLDYRNLCYVITHGEEKD
:: :::::. : :::::::::.
XP_006 IDVAGNLDYKALSYVITHGEEKEE
310 320
>>NP_067046 (OMIM: 613993) myosin regulatory light chain (175 aa)
initn: 719 init1: 589 opt: 591 Z-score: 625.8 bits: 122.6 E(85289): 4e-28
Smith-Waterman score: 623; 51.2% identity (70.4% similar) in 203 aa overlap (24-226:7-174)
10 20 30 40 50 60
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA
: .. : :.:. .::::::::.:.:::::::
NP_067 MASRKAGTRGKVAATKQAQ-RGSSNVFSMFEQAQIQEFKE---
10 20 30
70 80 90 100 110 120
pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN
::. .::::::.: : :::.:.. ::...
NP_067 -------------------------------AFSCIDQNRDGIICKADLRETYSQLGKVS
40 50 60
130 140 150 160 170 180
pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK
: .:::.::..:. ::::::::::.:::::.::::::.:: ::..:: ::: :. : .:
NP_067 VPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKGVVNKDEFK
70 80 90 100 110 120
190 200 210 220
pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
. :.::::.:: ::.:::: : :. ::.::..:::.::::.::.
NP_067 QLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
130 140 150 160 170
>>XP_016863736 (OMIM: 160782) PREDICTED: myosin light ch (132 aa)
initn: 631 init1: 584 opt: 584 Z-score: 619.8 bits: 121.1 E(85289): 8.7e-28
Smith-Waterman score: 584; 66.4% identity (86.3% similar) in 131 aa overlap (96-226:1-131)
70 80 90 100 110 120
pF1KE0 ERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEE
::::::::::::::.::.:.::. :::..:
XP_016 MDQNRDGFIDKEDLKDTYASLGKTNVKDDE
10 20 30
130 140 150 160 170 180
pF1KE0 LEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIKEKLMT
:.::.::: ::::::.::..:::::.::: :::::.:::..: .::: .. . ::. ::.
XP_016 LDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMS
40 50 60 70 80 90
190 200 210 220
pF1KE0 QADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
:::... ::: ::: :: :::::. : :::::::::.
XP_016 QADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
100 110 120 130
>>XP_016863737 (OMIM: 160782) PREDICTED: myosin light ch (132 aa)
initn: 631 init1: 584 opt: 584 Z-score: 619.8 bits: 121.1 E(85289): 8.7e-28
Smith-Waterman score: 584; 66.4% identity (86.3% similar) in 131 aa overlap (96-226:1-131)
70 80 90 100 110 120
pF1KE0 ERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEE
::::::::::::::.::.:.::. :::..:
XP_016 MDQNRDGFIDKEDLKDTYASLGKTNVKDDE
10 20 30
130 140 150 160 170 180
pF1KE0 LEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIKEKLMT
:.::.::: ::::::.::..:::::.::: :::::.:::..: .::: .. . ::. ::.
XP_016 LDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMS
40 50 60 70 80 90
190 200 210 220
pF1KE0 QADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
:::... ::: ::: :: :::::. : :::::::::.
XP_016 QADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
100 110 120 130
>>NP_006088 (OMIM: 609905) myosin regulatory light polyp (172 aa)
initn: 495 init1: 369 opt: 502 Z-score: 533.5 bits: 105.5 E(85289): 5.6e-23
Smith-Waterman score: 543; 46.5% identity (67.3% similar) in 202 aa overlap (26-226:5-171)
10 20 30 40 50 60
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA
.: .. :. :.::::.::::::::::::
NP_006 MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKE---
10 20 30
70 80 90 100 110 120
pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN
::...:::::::::::::.: .:.::. :
NP_006 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N
40 50 60
130 140 150 160 170 180
pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK
.: ::.:..:::::::::.:::::::::.:::::..: .:: :: :..::.. : ..
NP_006 PTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLR
70 80 90 100 110 120
190 200 210 220
pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD
: : :..:::..::: .:. : : ::..: .. .. :: ..::
NP_006 ELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD
130 140 150 160 170
>>NP_001138416 (OMIM: 609211) myosin regulatory light ch (172 aa)
initn: 476 init1: 350 opt: 485 Z-score: 515.8 bits: 102.3 E(85289): 5.4e-22
Smith-Waterman score: 528; 45.0% identity (65.8% similar) in 202 aa overlap (26-226:5-171)
10 20 30 40 50 60
pF1KE0 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA
.: .. :. :.::::.::::::::::::
NP_001 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKE---
10 20 30
70 80 90 100 110 120
pF1KE0 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN
::...:::::::::::::.: .:.::. :
NP_001 -------------------------------AFNMIDQNRDGFIDKEDLHDMLASLGK-N
40 50 60
130 140 150 160 170 180
pF1KE0 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK
. :.::..:::::::::.:::::::::.:::::..: .:: :: :. : .. : ..
NP_001 PTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR
70 80 90 100 110 120
190 200 210 220
pF1KE0 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHG-EEKD
: : :..:::..::: ... : : ::..: .. .. :: ..::
NP_001 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
130 140 150 160 170
226 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:18:56 2016 done: Thu Nov 3 21:18:57 2016
Total Scan time: 6.700 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]